Gene Information

Name : BBR47_03360 (BBR47_03360)
Accession : YP_002769817.1
Strain : Brevibacillus brevis NBRC 100599
Genome accession: NC_012491
Putative virulence/resistance : Resistance
Product : heavy metal-transporting ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 332548 - 334617 bp
Length : 2070 bp
Strand : +
Note : -

DNA sequence :
ATGGATTGCAGTTCGTGCGCCAAATCGCTGGAAAAGCATATGCATACGTTGCCTGCGGTAAAAGAGGTAAACGTGAACTT
TTCCACGGGTAAAATGCAGCTCGTCGCGGATGGGCTAGGAGAAGATGCGGTGGTCAAGGAAGTCGCAAAGGCCGGATATA
GTGCCATGCTACTTACGAGGCGCACGGCCAAAGCAGTTCCGAAAACGGATCAAGCAGGGACGACGCTGACGGTGATTTCT
GGTGTGTTGTTGGCTCTCGGTTTTCTAGGTTCCTTATCGTCTGGCATACCTCCGCTGGTCGTTACTGTTCTCTATGCGTT
GTCGATCATAAGCGGCGGCTACCGACCTGCACGCAGTGCTTTTTACGCGATAAAAAGCGGTTCACTGGATATGAACGTAT
TGATGTCTGTTGCGGCTGTTGGAGCCGCATTAATCGGTGAGTGGCTGGAGGGCGCAACAGTAGTCTGGCTCTTTTCCATC
GGAAACTTGCTGCAGACCAAGTCGATTGAAAAAACGCGCGACTCCATACGTAATCTGATGGATTTGGCTCCGCCTGAAGC
ATGGGTCAAGGTGGGGGAGTCTCTTACCCGCAAACCGGTTGAGGACATCACAGTCGGTCAAGTCATCGTAGTGAAGCCGG
GAGAGAAAATCCCGCTGGATGGTGTCATCGTACACGGGACATCGAGCGTCAATCAGGCCCCGATTACAGGTGAATCGATT
CCCGTAGATAAGCTGGTCGGGGACAGTGTTTTTGCAGGAAGTGTCAACGAGAGTGGCGCGGTGGAGATCAAGGTAACAAA
GCTGGTGGAAGATACAGCGATTGCCAGAATCATTCATCTCGTGGAGGAAGCGCAGGAAAAAAAAGCGCCTACTCAGGCGT
TCGTCGACAAATTCGCTACGATCTACACGCCAATCGTGCTCGTGCTTGCTTTGCTCGTGATTGTATTCCCGCCATTACTC
GGACTCGGTACCTGGGGAGAATGGTTTTACAGAGGGCTTGAGCTGCTAGTCGTTGCTTGCCCGTGCGCACTGGTCATTTC
TACGCCAGTTGCGATTGTGTCCGCGATTGGAAATGCCGCGAGAAACGGCGTCCTGATCAAGGGTGGTACGTTTTTGGAAA
AGGCAGGAGCGATTACCGCAATTGCTTTCGATAAAACGGGCACATTGACGGAAGGAAAACCACAGGTTGCGGCGGTTATC
GAGATGGAGGGAAGCGAGGACGACGTAGTGTCGATCGCCAGAACGATTGAAGAGCGATCTTCCCATCCGATTGCACTAGC
GATTCTCACCTATGCGAAACAAAAGCAGATTGCTTCCCAGAGTGGGCAAGATTTCAAGGCGATCGTCGGAAAAGGGGCGA
GCGCTGTCATCGGAACCGAAACATTTTATGCAGGAAAGCCCGCCCTGTTTCAAGAGCTGGGAGTCGATCTGTCGGCATGG
CAAACGAAAGTCGAGTCGTTGCAGAGTGAGGGACATACACTGGTGGTTATCGGTACCGCAACGAAATTGATCGGGATGAT
TGCCGTTGCCGATACCATTCGTGAGATTACGGTTAGTGCCATTGGCAAGCTCAAGGCCGCAGGAATCGAAGACATCGTGA
TGCTGACCGGTGACAATACGGGTACGGCGAAAAAAGTAGCGAGTCAGACAGGCGTCAATCGTTATTTTGCAGAGCTGCTG
CCACAAGATAAGGTAGAAGCGGTCAAGCGACTACAGCAAGAAGGCAAGGTCGTCGCCATGGTGGGTGACGGGATCAATGA
TGCACCTGCTCTCGCATCAGCTGACTTGGGGATTGCGATGGCTGGAGCAGGTACTGATACAGCAATGGAAACCGCGGATA
TTGTACTGATGGCTGACAATCTCGAAAAGCTGCCGCACACGATGAAGATCAGCAGAAAAGCACTCACGATTATCAAGCAA
AACATCTGGTTTTCGATCATCGTGAAGCTGATTGCACTCGTGCTGATATTCCCAGGCTATCTAACCTTGTGGCTGGCGGT
GCTCAGTGACACGGGAGCGGCTTTGCTGGTCATCTTAAACAGTATGAGACTCTTGCGTATGAAAGGCTAA

Protein sequence :
MDCSSCAKSLEKHMHTLPAVKEVNVNFSTGKMQLVADGLGEDAVVKEVAKAGYSAMLLTRRTAKAVPKTDQAGTTLTVIS
GVLLALGFLGSLSSGIPPLVVTVLYALSIISGGYRPARSAFYAIKSGSLDMNVLMSVAAVGAALIGEWLEGATVVWLFSI
GNLLQTKSIEKTRDSIRNLMDLAPPEAWVKVGESLTRKPVEDITVGQVIVVKPGEKIPLDGVIVHGTSSVNQAPITGESI
PVDKLVGDSVFAGSVNESGAVEIKVTKLVEDTAIARIIHLVEEAQEKKAPTQAFVDKFATIYTPIVLVLALLVIVFPPLL
GLGTWGEWFYRGLELLVVACPCALVISTPVAIVSAIGNAARNGVLIKGGTFLEKAGAITAIAFDKTGTLTEGKPQVAAVI
EMEGSEDDVVSIARTIEERSSHPIALAILTYAKQKQIASQSGQDFKAIVGKGASAVIGTETFYAGKPALFQELGVDLSAW
QTKVESLQSEGHTLVVIGTATKLIGMIAVADTIREITVSAIGKLKAAGIEDIVMLTGDNTGTAKKVASQTGVNRYFAELL
PQDKVEAVKRLQQEGKVVAMVGDGINDAPALASADLGIAMAGAGTDTAMETADIVLMADNLEKLPHTMKISRKALTIIKQ
NIWFSIIVKLIALVLIFPGYLTLWLAVLSDTGAALLVILNSMRLLRMKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 2e-145 50
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 2e-145 49
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 3e-142 47

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BBR47_03360 YP_002769817.1 heavy metal-transporting ATPase BAC0298 Protein 1e-112 46
BBR47_03360 YP_002769817.1 heavy metal-transporting ATPase BAC0092 Protein 2e-96 43
BBR47_03360 YP_002769817.1 heavy metal-transporting ATPase BAC0124 Protein 8e-81 41