Gene Information

Name : aadK (BBR47_23140)
Accession : YP_002771795.1
Strain : Brevibacillus brevis NBRC 100599
Genome accession: NC_012491
Putative virulence/resistance : Resistance
Product : aminoglycoside 6-adenylyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.-
Position : 2402585 - 2403445 bp
Length : 861 bp
Strand : +
Note : -

DNA sequence :
ATGGCTTTGAGAACGGAACAAGAAATGATGAACATGCTGATTGATTTCGCTAGGAAGGATGATCGAATCCGCTTGGTAAC
CTTGGAAGGGTCACGCACGAACAAAAATATACCAGCTGATCCTTTCCAAGATTATGATGTTTCGTATTTTGTGACTGAGA
TGGCTTCTTTCAAGGAAAATGATCAATGGCTCGATGTTTTTGGGAATCGGATCATGATGCAAAAACCGGAGGATATGGAG
CTTTTTCCGTCCGAGTTAGGGAATTGGTTTTCCTATCTCATGCTATTTGAGGATGGAAATAAAGTGGATCTGACGCTGAT
CCCGATAGACGAGACAGAGCAGTATTTTGCAGAAAGCGACGGTCTGGTTGAGATTTTGCTAGATAAAGACGAGCTTATCA
AACACGAGGTGCTCCCTTCCGATCGCCAATATTGGACCCGGAAGCCAAGTGCCAGAGAGTTTGATGACTGCTGCAATGAA
TTTTGGATGGTATCTACTTATGTTGTCAAAGGTTTGGCGAGAAAAGAAATTCTGTTTGCGATTGACCATCTCAACGAAAT
TGCCCGACCAAATTTGCTCCGCATGATGGCTTGGCAAATCGGATGTGAGAAAGGATTTACCTTTAGTGTCGGGAAAAACT
ACAAATTTATCGATCGCTATCTTCCAAAAGAAGACTGGGAAGCGTTACTATCCAGCTATAACGAAAACGGCTACCCGCAG
ATGTGGGAATCGTTATTCATTTGCTATGAGCTATTTCGAAAGTACTCCAAAGCGGTGGCAGAAAATCTCGAATATCCGTA
TCCAGATTACGATGAAGCCATTACCAAGTACGCGGAACATATCTACCATTCATGGAAATGA

Protein sequence :
MALRTEQEMMNMLIDFARKDDRIRLVTLEGSRTNKNIPADPFQDYDVSYFVTEMASFKENDQWLDVFGNRIMMQKPEDME
LFPSELGNWFSYLMLFEDGNKVDLTLIPIDETEQYFAESDGLVEILLDKDELIKHEVLPSDRQYWTRKPSAREFDDCCNE
FWMVSTYVVKGLARKEILFAIDHLNEIARPNLLRMMAWQIGCEKGFTFSVGKNYKFIDRYLPKEDWEALLSSYNENGYPQ
MWESLFICYELFRKYSKAVAENLEYPYPDYDEAITKYAEHIYHSWK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSU98_0964 YP_001200522.1 aminoglycoside 6-adenylyltansferase Not tested 89K Protein 4e-82 58
SSU05_0957 YP_001198323.1 aminoglycoside 6-adenylyltansferase Not tested 89K Protein 4e-82 58
aadE YP_003446812.1 streptomycin aminoglycoside 6-adenyltransferase Not tested The aminoglycoside resistance gene cluster Protein 5e-84 58
aadE AFJ97257.1 streptomycin aminoglycoside 6-adenyltransferase Not tested Not named Protein 6e-59 58
aadE AFJ97264.1 putative adenyltransferase Not tested Not named Protein 2e-77 57

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aadK YP_002771795.1 aminoglycoside 6-adenylyltransferase NC_006663.1.orf0.gen Protein 1e-77 60
aadK YP_002771795.1 aminoglycoside 6-adenylyltransferase AJ489618.1.orf2.gene Protein 3e-61 59
aadK YP_002771795.1 aminoglycoside 6-adenylyltransferase FN594949.1.gene25.p0 Protein 9e-78 57