Gene Information

Name : clpC (BBR47_01880)
Accession : YP_002769669.1
Strain : Brevibacillus brevis NBRC 100599
Genome accession: NC_012491
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 201381 - 203828 bp
Length : 2448 bp
Strand : +
Note : -

DNA sequence :
ATGTTTGGACGTTTTACAGAACGCGCACAAAAAGTACTGGCGCTTGCCCTGGAAGAGGCGGTTCGTCTCGGACACAAAGA
TATTGGGACAGAGCATGTGCTGCTGGGACTCATTCGAGAAGGCGAAGGAATTGCGGCGAAGGCACTGCAATCACTTGGGC
TTGGCCTCGATAAAATCCAGAGTGAAGTGGAGTCGTTAATCGGGCGAGGAACAGAGCAGTCCGGTAGTAATTACACACCA
AACTATACACCTCGCGCCAAAAAGGTCATTGAACTGTCGATGGACGAAGCCCGCAAGCTGGGTCATACCTATGTGGGGAC
TGAACATATTCTGCTTGGCTTGATCCGTGAGGGAGAAGGCATTGCTGCGAGAATCATGAACAATTTGGGCGTTAGCCTGA
ACAAGGCACGGCAACAGGTGCTCCAGCTGCTGGGCAGCTCGGAAATGATGGCATCTCATCAACCGTCTGGAGGGAATCCA
GCGGCGAATACGCCGACATTGGACGGCTTGGCAAGGGATCTGACTGCAATCGCTCGTGACGGCGGTCTGGACCCGGTTAT
CGGTCGCCAAAAAGAAATCGAGCGTGTGATCCAAGTACTTAGCAGACGTACCAAGAACAACCCTGTTTTAATTGGGGAGC
CTGGTGTCGGGAAAACAGCTATCGCAGAAGGTCTTGCCCAAAAAATCGTGAACAACGAAATTCCGGAGACCCTTCGTGAT
AAGCGCGTCATGACCCTCGATATGGGAACCGTTGTTGCGGGAACCAAATATCGCGGTGAGTTCGAAGATCGTCTGAAAAA
AATCATGGACGAAATTCGCCAAGCAGGAAACATCATCCTGTTTATTGATGAGCTGCACACCCTGATTGGTGCTGGTGGAG
CAGAAGGCGCAATTGACGCCTCTAACATTTTGAAGCCTGCGCTGGCTCGTGGTGAGCTACAGTGCGTAGGTGCTACAACG
CTGGATGAATATCGCAAGTACATCGAAAAAGACGCGGCACTGGAGCGTCGTTTCCAACCGATTCAGGTTGATGAACCGAC
AGCGGAGGATGCCATTCGTATCCTGCATGGCCTTCGTGATCGTTATGAAGCCCACCACCGTGTCAAAATTACCGATGAAG
CAATCGAGCAGGCAGTAAAGCTGTCTGACCGCTATATTACGGAACGCTTCCTGCCTGACAAGGCCATCGACTTGGTTGAC
GAGGCGGCATCGAAAGTCCGCTTGCAATCCTTTACCGTTCCGCCAAACCTCAAAGAGCTGGAGGGACGTCTGGAAGAGGT
GCGCAAGGAAAAAGACGCTGCCGTACAATCACAAGAGTTCGAGGAAGCAGCAGCACTTCGCGATCAGGAGCAAAAACTGC
GTGAAGAACTGGATAAAACGAAAAAAGACTGGAAAGAACGCCAAGGCCAGCTGAACATGGAGGTTACGCCAGAAGACATC
GCGCAAGTAGTGGCGAGCTGGACGGGTATTCCTGTGTTAAAGCTGAAGGAAGAAGAAACAGAGCGCTTGTTGAAGATGGA
AGAGATTTTGCACGATCGCGTTATTGGTCAAGATGAAGCAGTCAAATCCATTTCGCGTGCGATCCGCCGTGCCCGTGCTG
GTTTGAAAGACCCAAAACGCCCAATCGGCTCGTTTATCTTCCTGGGGCCTACCGGTGTGGGTAAAACCGAATTGGCTCGT
GCCGTGGCGGAGACGCTTTTCGGTGACGAGGATGCCATGATCCGCGTGGATATGTCCGAGTACATGGAGAAGCATTCCAC
CGCTCGTCTGGTAGGTGCCCCTCCAGGCTACGTAGGCTTTGACGAGGGCGGTCAGCTGACCGAAAAAGTGCGCCGTAAGC
CTTACTCCGTCATTTTACTGGACGAAATCGAGAAAGCTCACCCAGACGTATTCAACATCCTGCTACAAGTTCTGGATGAT
GGTCGTTTGACAGACTCCAAGGGACGTACCGTCGACTTCCGCAATACGGTTGTCATCATGACTTCCAACGTCGGAGCCAG
CATGATCAAGAAAAATACAACGCTCGGCTTCACGACCAATGATTCGGAAAGAAAGTATCAGGATATGAAGGACAAAGTCA
TGGATGAGCTGAAGAAGAGCTTCCGTCCTGAGTTCTTGAACCGTATCGACGAAGTCATCGTGTTCCACTCCTTGGAGCAA
GAGCATATCGAGCAAATCGTAACTCTCATGACAGATGAGCTGCGTAAACGTTTGAAAGAGCAGGACATTGATTTCCAATT
GACCGAAGAAGCCAAGAAAGTATTGGCAAAAGAAGGCTTTGATCCGGCCTATGGTGCACGTCCTCTGCGTCGAGCTATCC
AGCGCCACATCGAGGATAATTTGTCCGAGGAATTGCTCAAGGGCACGATCAGTAAAGGCGATACCGTCAATATCGAAGCG
GAAGAAGGCAAGCTGGTAGTCAAGCGCCTTGAAAAAACGAAATCATAA

Protein sequence :
MFGRFTERAQKVLALALEEAVRLGHKDIGTEHVLLGLIREGEGIAAKALQSLGLGLDKIQSEVESLIGRGTEQSGSNYTP
NYTPRAKKVIELSMDEARKLGHTYVGTEHILLGLIREGEGIAARIMNNLGVSLNKARQQVLQLLGSSEMMASHQPSGGNP
AANTPTLDGLARDLTAIARDGGLDPVIGRQKEIERVIQVLSRRTKNNPVLIGEPGVGKTAIAEGLAQKIVNNEIPETLRD
KRVMTLDMGTVVAGTKYRGEFEDRLKKIMDEIRQAGNIILFIDELHTLIGAGGAEGAIDASNILKPALARGELQCVGATT
LDEYRKYIEKDAALERRFQPIQVDEPTAEDAIRILHGLRDRYEAHHRVKITDEAIEQAVKLSDRYITERFLPDKAIDLVD
EAASKVRLQSFTVPPNLKELEGRLEEVRKEKDAAVQSQEFEEAAALRDQEQKLREELDKTKKDWKERQGQLNMEVTPEDI
AQVVASWTGIPVLKLKEEETERLLKMEEILHDRVIGQDEAVKSISRAIRRARAGLKDPKRPIGSFIFLGPTGVGKTELAR
AVAETLFGDEDAMIRVDMSEYMEKHSTARLVGAPPGYVGFDEGGQLTEKVRRKPYSVILLDEIEKAHPDVFNILLQVLDD
GRLTDSKGRTVDFRNTVVIMTSNVGASMIKKNTTLGFTTNDSERKYQDMKDKVMDELKKSFRPEFLNRIDEVIVFHSLEQ
EHIEQIVTLMTDELRKRLKEQDIDFQLTEEAKKVLAKEGFDPAYGARPLRRAIQRHIEDNLSEELLKGTISKGDTVNIEA
EEGKLVVKRLEKTKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 59
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 8e-91 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_002769669.1 negative regulator of genetic competence VFG0079 Protein 0.0 74
clpC YP_002769669.1 negative regulator of genetic competence VFG0080 Protein 1e-148 51