Gene Information

Name : leuS (BBR47_19950)
Accession : YP_002771476.1
Strain : Brevibacillus brevis NBRC 100599
Genome accession: NC_012491
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 2077493 - 2079910 bp
Length : 2418 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGGTATTCAGTCATCGTAATGTCGAAAAGAAGTGGCAGCAATATTGGGAGCAGAACAAGACCTTCAAAACCTCCGAGGA
TGAGGGCAAGAAAAAGTTTTACGCACTCGACATGTTCCCGTATCCATCTGGAGCTGGCCTGCACGTAGGACATCCGGAAG
GCTATACGGCTACTGATATTTTGTCCCGCATGAAGCGGATGCAAGGATATAACGTTCTCCATCCAATGGGCTGGGATGCG
TTTGGTTTGCCAGCGGAGCAATACGCGCTCGATACAGGAAACGATCCGGCGGAATTCACCGAGCACAATATCAACACCTT
CCGTCGCCAAATTAAGTCTCTCGGATTTTCCTACGACTGGGATCGTGAAATTAACACAACTGATCCGCATTACTACAAGT
GGACACAATGGATTTTTACGAAGCTGTATGAGCACGGCTTGGCTTATATTGACGAGGTAGCTGTAAACTGGTGCCCTGCT
TTGGGAACGGTTTTGGCGAACGAAGAAGTGATTGATGGAAAAAGTGAGCGTGGCGGACACCCAGTAGAACGCCGCCCAAT
GAAGCAATGGGTCTTGAAAATTACTGCGTATGCGGAAAGACTGCTCGCTGACCTGGATGAACTGGATTGGCCAGAGAGCA
TCAAGGAAATGCAACGCAACTGGATCGGCCGTTCTGAAGGGGCAGAAGTAACCTTTGGTATCGAAGGTCATGATGAATCC
TTTACCGTCTTTACGACTCGTCCAGACACTCTTTACGGGGCAACCTATGCGGTACTGGCTCCTGAGCACAAGCTGGTTGA
ACAAATTACCGTACCGGCTCAAAAAGAAGCAGTAGAAGCGTACCTGGATCAAGCAAAGCGCAAGAGCGATTTGGAACGTA
CTGATCTGGCAAAAGAAAAGACAGGAGTATTTACTGGAGCGTATGCGATCAACCCGGTTAACGGCGAGCGTCTGCCAATC
TGGATTGCAGATTACGTGCTGATCAGCTACGGAACAGGCTCCATCATGGCGGTTCCAGCGCACGATGAACGCGACTATGA
GTTCGCGAAAACATTCGATCTGCCAATCAAGCAAGTCATCGCTGGTGGCGATATCTCCAAAGAAGCGTATGCAGGCGACG
GAGAGCACATTAACTCTGGCATGCTCGATGGTTTGAACAAAGAACAGGCGATCAGCAAAATGATTGAGTGGCTGGAAGCA
GAAGGCAAAGGAAATCGCAAGGTAACGTACCGTCTGCGCGACTGGCTGTTTAGCCGTCAACGTTACTGGGGTGAACCAAT
TCCGATTCTCCACCTGGAAGATGGCACGATGAAAGTCGTTCCAGAATCCGAATTGCCAATCATGTTGCCAAAAACAAAAG
AAATCAAACCATCCGGTACAGGTGAATCGCCATTGGCAAACATCGCGGAGTGGGTCAACACTATCGATCCGGAAACAGGC
ATGAAAGCACGCCGTGAGACAAACACGATGCCGCAATGGGCGGGTAGCTGCTGGTACTTCCTGCGCTTCATCGATCCACA
CAATGACAAGGCATTGGCTGATCCAGACAAACTGAAAGAATGGCTGCCAATCGACATTTACATTGGTGGTGCAGAGCATG
CGGTACTGCACTTGCTCTACTCTCGTTTCTGGCACAAGTTCCTGTACGATATCGGTGTCGTACCTACAAAGGAACCATTC
CAAAAGCTGTTTAACCAAGGGATGATCCTGGGTGAAAACAACGAGAAAATGAGTAAGTCCAAAGGCAACGTCGTAAACCC
AGACGATATCATCGACAGCCATGGTGCCGATACACTACGCATGTACGAAATGTTCATGGGGCCACTGGATGCTTCGATCG
CTTGGTCGACAAAAGGCTTGGATGGCGCACGCCGCTTCCTGGATCGCGTATATCGTCTGTTTGTGGGTGATAACGGTGAG
CTGAACGAAAAAATCGTGGAAACCTCCAACGTAGCTGGCATGGAGCGCGTGTACCACCAAACTGTGAAAAAAGTAACAGA
AGACTACGAGGGCCTGCGTTTCAATACAGGTATCTCTCAGTTGATGGTATTCGTAAACGAAGCGTACAAAGCAGAAGTTT
TGCCGAAGAAATTCATGGAGGACTTTGTAAAAATGCTGTCTCCAATCGCTCCGCACTTGGGTGAAGAGCTGTGGGAAAAA
CTCGGTCACAGCGAGAGCGTGGCATACGCAGCATGGCCTACGTATGACGAAGCGAAGCTGGTTGAAGACGAGGTAGAAAT
CGTCCTGCAAATTAACGGCAAAAACAAAGAAAAGCTGCTCATCGCTTCTGATTCGACGAAAGAACAGATGGAAGAGATGG
CGAAAAACAACGAGATGATTAACGAACTGATCGAAGGAAAAACGATCGTCAAAGTCATCGCTGTTCCAGGCAAACTGGTG
AATATCGTCGTTCGTTAA

Protein sequence :
MVFSHRNVEKKWQQYWEQNKTFKTSEDEGKKKFYALDMFPYPSGAGLHVGHPEGYTATDILSRMKRMQGYNVLHPMGWDA
FGLPAEQYALDTGNDPAEFTEHNINTFRRQIKSLGFSYDWDREINTTDPHYYKWTQWIFTKLYEHGLAYIDEVAVNWCPA
LGTVLANEEVIDGKSERGGHPVERRPMKQWVLKITAYAERLLADLDELDWPESIKEMQRNWIGRSEGAEVTFGIEGHDES
FTVFTTRPDTLYGATYAVLAPEHKLVEQITVPAQKEAVEAYLDQAKRKSDLERTDLAKEKTGVFTGAYAINPVNGERLPI
WIADYVLISYGTGSIMAVPAHDERDYEFAKTFDLPIKQVIAGGDISKEAYAGDGEHINSGMLDGLNKEQAISKMIEWLEA
EGKGNRKVTYRLRDWLFSRQRYWGEPIPILHLEDGTMKVVPESELPIMLPKTKEIKPSGTGESPLANIAEWVNTIDPETG
MKARRETNTMPQWAGSCWYFLRFIDPHNDKALADPDKLKEWLPIDIYIGGAEHAVLHLLYSRFWHKFLYDIGVVPTKEPF
QKLFNQGMILGENNEKMSKSKGNVVNPDDIIDSHGADTLRMYEMFMGPLDASIAWSTKGLDGARRFLDRVYRLFVGDNGE
LNEKIVETSNVAGMERVYHQTVKKVTEDYEGLRFNTGISQLMVFVNEAYKAEVLPKKFMEDFVKMLSPIAPHLGEELWEK
LGHSESVAYAAWPTYDEAKLVEDEVEIVLQINGKNKEKLLIASDSTKEQMEEMAKNNEMINELIEGKTIVKVIAVPGKLV
NIVVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 66