Gene Information

Name : metB (RER_42650)
Accession : YP_002767712.1
Strain : Rhodococcus erythropolis PR4
Genome accession: NC_012490
Putative virulence/resistance : Resistance
Product : probable cystathionine gamma-synthase/cystathionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 4681784 - 4682956 bp
Length : 1173 bp
Strand : -
Note : bifunctional protein

DNA sequence :
ATGAGTGAGCAACGCAGCAAGGCCGACAACATCAGCTGGCAGGGTTTCTCCACGAAAGCGGTGCATGCGGGTTACGAACC
CGATCCGCTGACCGGCGCGGTCAACGTGCCGATCTACGCAAGTTCCACCTTCGCCCAAGACGGCGTCGGTGGAATGCGCA
GTGGCTTCGAGTACGCGCGAACGGGCAACCCCACCCGTCGCCCGCTCGAGGCGAACCTTGCCGCGCTCGAATCCGGAACC
TACGGCCGAGCGTTCAGTTCGGGAATGGCGGCCACCGACTGCCTGCTCCGTTCGGTACTTCGACCGGGCGATCACCTGGT
CATCCCCGACGACGCGTATGGCGGAACCTTCCGTCTCATCGACAAGGTGTTCACGCAGTGGGGGATCGAGTACACCCCGG
CTCCGGTGTCCGACGTCGATGCGGTGCGCGCGGCGATGAAGTCCAACACCAAGCTGGTCTGGGTCGAGACGCCCACGAAC
CCGCTGCTCAATATCGGTGACATCGAGCTCCTTGCCGAGGTCGCCCACGAGGGCAACGCAAAGATCGTGGTGGACAACAC
CTTCGCGTCGCCGTACCTGCAGCAGCCGCTGCAGCTCGGTGCCGACATCGCGCTGCACTCCACGACCAAGTACATCGGCG
GACACTCCGACGTGGTCGGTGGCGCTCTCGTCTGCAACGACGAAGAACTGGATACCGCGTTTGCCTTCCTGCAGAACGGA
TCCGGCGGCGTTCCCGGCCCGTTCGACGCGTTCCTGACGTTGCGCGGAATCAAGACACTGGCGCTGCGCATGGAGCGTCA
CAGTGACAACGCGGAGAAGGTCGTCGAATTGCTCGACGGCCACCCCGCGGTTGCCAGCGTCATCTACCCGGGCCTGGCTT
CGCATCCGTCACACAAGGTCGCGGCCAAGCAGATGCGACGCTTCGGCGGCATGATCTCCGTCCGCCTCAAGGGCGGCAAG
GCGGCAGCTCTCGACCTGTGCTCGCGCACCGAGATCTTCACGCTGGCAGAATCTCTCGGCGGCGTCGAATCTCTCATCGA
GTTCCCCGGCGCGATGACCCACGCCTCGACGGCCGGTTCCGCTCTCGAGGTTCCCGACGATCTGGTTCGCCTGTCGGTCG
GCATCGAAGACGCCTCCGATCTGGTCGGCGACATCGAGCAAGCGCTGTCCTGA

Protein sequence :
MSEQRSKADNISWQGFSTKAVHAGYEPDPLTGAVNVPIYASSTFAQDGVGGMRSGFEYARTGNPTRRPLEANLAALESGT
YGRAFSSGMAATDCLLRSVLRPGDHLVIPDDAYGGTFRLIDKVFTQWGIEYTPAPVSDVDAVRAAMKSNTKLVWVETPTN
PLLNIGDIELLAEVAHEGNAKIVVDNTFASPYLQQPLQLGADIALHSTTKYIGGHSDVVGGALVCNDEELDTAFAFLQNG
SGGVPGPFDAFLTLRGIKTLALRMERHSDNAEKVVELLDGHPAVASVIYPGLASHPSHKVAAKQMRRFGGMISVRLKGGK
AAALDLCSRTEIFTLAESLGGVESLIEFPGAMTHASTAGSALEVPDDLVRLSVGIEDASDLVGDIEQALS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-77 47
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 8e-79 47
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 6e-57 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_002767712.1 probable cystathionine gamma-synthase/cystathionine gamma-lyase BAC0207 Protein 1e-64 41