Gene Information

Name : hemC (GAU_2594)
Accession : YP_002762106.1
Strain : Gemmatimonas aurantiaca T-27
Genome accession: NC_012489
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 3045853 - 3046782 bp
Length : 930 bp
Strand : -
Note : protein synonym: HMBS; protein synonym: PBG; protein synonym: hydroxymethylbilane synthase; protein synonym: pre-uroporphyrinogen synthase

DNA sequence : 
ATGATGACTGTCCCCGTCCGAATCGGTACCCGCAGCTCCGAACTCGCCCTGCGTCAGGCGCGACAGGTTGCCGCGCAGCT
CGATGCGCGTGGTGTGCCCAGTGAACTGGTGGAGTACACCACCCTCGGCGATCGCATTCTCGATCGCCCACTCTCGGCCA
TCGGTGAGAAGGGATTGTTCACGGCCGAACTCGAAGCCGACCTGCTCGCCGGGCGCATCGACTGCGCCGTGCATTCACTC
AAGGATCTGCCCACGGCCGACCCGCAGGGCATCATCGTCGTGGCATTGCTGGAACGTGAGGATCCGCGGGACGCGCTGGT
GGTGCGCGCCGGTGTCGACGCACACAGCCTCGACACATTGCCGGAGGGCGCCCGTGTCGGCACGTCTTCGTTGCGTCGTC
GCGCACAGTTGCAGGCGTTGCGCAGTGATCTCGAGGTGTGCGAACTGCGGGGCAATGTGGGGACACGCCTGCGCAAGCTC
GATGAAGGTCAGGTGGATGCCGCGCTGCTGGCAGCGGCCGGGCTGCATCGTCTCGGGCTGGCGGATCGCATTGTGGCGTA
CCTCGATGCGCCGGAATGGCTGAGTGCACCCGGGCAGGGGGCAATTGCCGTACAAGGGCGCGCTGATGACGAGGCCCTGC
TTTCCACGTTGTCTTCGCTCGATCACGCACCCACGCGTGTCGCCGTGACGGCAGAACGCGCCTTGCTTGCCGCGCTGGAA
GGTGGATGCCAGGTACCTATTGGTGCGGCGGTACTGGAAGAACCGGAATACGGCACGATCCTGCACGCGGTGATCGTTTC
TCTGGATGGTTCGTCTGCCGTGCGCGGTGGATATCCCGTTGATCATGCCAACCCTGCGGCATCCGGCATCGAGTTGGCCC
GACAACTGCGGGCAGCCGGTGGTGCACAGATTCTTTCGGAGATCCGATGA

Protein sequence : 
MMTVPVRIGTRSSELALRQARQVAAQLDARGVPSELVEYTTLGDRILDRPLSAIGEKGLFTAELEADLLAGRIDCAVHSL
KDLPTADPQGIIVVALLEREDPRDALVVRAGVDAHSLDTLPEGARVGTSSLRRRAQLQALRSDLEVCELRGNVGTRLRKL
DEGQVDAALLAAAGLHRLGLADRIVAYLDAPEWLSAPGQGAIAVQGRADDEALLSTLSSLDHAPTRVAVTAERALLAALE
GGCQVPIGAAVLEEPEYGTILHAVIVSLDGSSAVRGGYPVDHANPAASGIELARQLRAAGGAQILSEIR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 1e-30 48
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 1e-30 48