Gene Information

Name : leuS (Lm4b_01673)
Accession : YP_002758370.1
Strain : Listeria monocytogenes Clip81459
Genome accession: NC_012488
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 1695242 - 1697653 bp
Length : 2412 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
GTGACATTTAATCACAAAAAAATGGAACCAAAATGGCAACAATATTGGAGTGAACATAACACTTTCAAAACAACAGAAGA
TAAAAATAAAGATAACTTCTATGCACTAGATATGTTCCCTTACCCATCTGGAGCAGGTCTTCACGTAGGACATCCAGAAG
GTTATACAGCAACAGATATTTTGTCTCGTATGAAACGAATGCAAGGGAAGAACGTCCTTCATCCAATCGGTTGGGATGCT
TTTGGTCTTCCTGCAGAGCAATATGCAATTGATACTGGTAACGACCCAGAAGAATTTACCGCACTGAATATTGCCAACTT
TACTCGCCAAATTAAATCACTTGGTTTTTCCTACGACTGGGACCGTGAAATCAATACAACAGATCCTGAATATTATAAAT
GGACACAGTGGATTTTTGAAAAACTATATGAAAAAGGTTTAGCTTATGAAGCCGAAATCGCTGTAAACTGGTGTCCGGCA
CTTGGTACTGTTTTAGCCAATGAAGAAGTTATCGATGGCAAAAGTGAACGCGGTGGCTTCCCAGTTTTCCGCAAACCAAT
GCGTCAATGGATGCTTAAAATTACCGCGTACGCAGATCGTTTGCTAGATGATCTTGATCTAGTGGATTGGCCTGAAAATA
TTAAAGATATGCAACGTAACTGGATTGGTCGTTCAGAAGGCGCAGAAGTTACTTTTAAAATTAAAGATAGCGATGAAACG
TTTAATGTCTTTACCACACGTCCAGATACACTTTTTGGCGCAACATATACCGTTTTTGCACCAGAACACGAACTTATCGA
AAAAATCACAACACCAGAACAAAAAGAAGCAGTTGAAGCTTATAAAAAACAAGTAGAACTTAAAAGCGAACTGGAAAGAA
CCGACCTTGCAAAAGATAAAACAGGTGTCTTCACAGGAGCTTATGCGATTAATCCAATCAACGGCGAAGAAGTGCCAATT
TGGATTGCGGACTACGTGTTGATTCAATATGGAACAGGTGCGATTATGGCCGTACCAGCTCACGATGAACGTGACTTTGA
ATTTGCGCAACAATTTGGTTTGAATATTCGTCCTGTTCTTGAAGGCGGCGACGTGACAAAAGAAGCATTCACTGGCGACG
GACCACATATTAACTCCGATTTCTTGAACGGACTAGCTAAAGCCGAAGCGATTACCGCTGCAATTGATTGGCTAGAAAAA
GAAGGCATCGGTAGCCGTAAAATCACGTATCGTTTGCGCGACTGGTTGTTCAGCAGACAACGTTACTGGGGTGAACCAAT
TCCAGTTATTCACTGGGAAGACGGGGAAACAACGCTTGTACCAGAAGACGAACTACCACTACTTCTGCCAAAAGCAACAG
AAATCAAACCATCAGGAACAGGCGAATCACCACTTGCTAACTTGCATGACTGGGTAAACGTAACAGACAAAAACGGTCGA
AAAGGTCGTCGCGAAACAAATACAATGCCACAATGGGCTGGCTCAAGCTGGTATTTCTTGCGTTATATCGATCCAAATAA
CAGCGAAGCAATTGCTGACAAAGAAAAACTAGCAGAATGGCTTCCAGTTGACGTTTATATCGGCGGGGCAGAGCATGCAG
TACTTCACCTTCTTTATGCACGTTTCTGGCATAAATTCTTGTACGATATCGGTGTAGTTCCAACAAAAGAACCTTTCCAA
AAACTATTTAACCAAGGTATGATTCTTGGCGAAAATAACGAAAAAATGTCCAAATCAAGAGGTAATGTTGTTAACCCTGA
TGAAGTAGTAGAAAAATACGGCGCAGACACACTTCGCTTGTACGAAATGTTCATGGGACCACTAGAAGCTTCGATTGCAT
GGAACGAAAATGGACTGGAAGGTGCACGTAAATTCCTAGACCGCATCTGGCGCTTGCTAGTAACTGAAGAAGGCACACTC
GCTGAAAAAGTGACAACTGATGCGAATGCTAACTTAGAAAAAGCATATCATCATATGGTGAAAACAGTTACCAACCATTA
CGAAAACCTGCGTTTCAATACCGGGATTTCGCAACTGATGATTTTCATCAATGAAGCATATAAACAAGATACGATTCCAA
AACAATATGTCGAAGGTTTCGTTCAACTCTTGTCACCAATCGCACCACACCTTGCAGAAGAATTATGGGAAATCCTAGGT
CACACCGAAACAATCAGCTACGTAGCTTGGCCAACATACGACGAAACAAAACTAGTAGAAGATGAAGTAGAAATCGTACT
TCAAGTAAACGGCAAAGTAAAAAGCAAAATCACCGTTGCCAAATCTCTCGAAAAAGAAGAACTAGAAAAAATTGCACAAG
AAGACAACAAAATGAAAGAAAACCTAGAAGGCAAAACAATCCGTAAAGTGATTGTCGTTCCAGGGAAACTTGTAAATATT
GTTGCGAACTAA

Protein sequence :
MTFNHKKMEPKWQQYWSEHNTFKTTEDKNKDNFYALDMFPYPSGAGLHVGHPEGYTATDILSRMKRMQGKNVLHPIGWDA
FGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDREINTTDPEYYKWTQWIFEKLYEKGLAYEAEIAVNWCPA
LGTVLANEEVIDGKSERGGFPVFRKPMRQWMLKITAYADRLLDDLDLVDWPENIKDMQRNWIGRSEGAEVTFKIKDSDET
FNVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKTGVFTGAYAINPINGEEVPI
WIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLEGGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEK
EGIGSRKITYRLRDWLFSRQRYWGEPIPVIHWEDGETTLVPEDELPLLLPKATEIKPSGTGESPLANLHDWVNVTDKNGR
KGRRETNTMPQWAGSSWYFLRYIDPNNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQ
KLFNQGMILGENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDRIWRLLVTEEGTL
AEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYKQDTIPKQYVEGFVQLLSPIAPHLAEELWEILG
HTETISYVAWPTYDETKLVEDEVEIVLQVNGKVKSKITVAKSLEKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNI
VAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 68