Gene Information

Name : guaA (Lm4b_01109)
Accession : YP_002757814.1
Strain : Listeria monocytogenes Clip81459
Genome accession: NC_012488
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1124379 - 1125935 bp
Length : 1557 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
TTGTTTAAAATTATGAAAGACTTTACCGAGCAAGAGAAAATTATCGTTCTAGATTTTGGTAGTCAGTACAATCAACTAAT
TACGCGCCGCATTCGTGAATTCGGTGTGTATAGTGAATTACATCCGCATACTATTACAGTTGAAGAAATGAAAGCACTAA
ATCCAACGGGGATTATTTTTTCAGGAGGACCTAACAGTGTGTATGACGAAGATGCCTTCCGCGCTGACGAAAGAATCTTT
GACATGGGAATTCCGATTTTGGGAATTTGTTACGGCATGCAATTAATGACAACGCACTTCGGTGGCAAAGTAGAACGTGC
GAAAGACCGCGAATACGGGAAAGCGGACATTCACGTTGAGAAGCCAAACCGTTTATTTGCTGGACTACCAACCGATCAAG
TTGTTTGGATGAGTCACGGCGATTTAGTCGTTGAGGAGCCTGCTGGTTTTGAAGTAACAATTACTAGTAAATCTTGCCCA
ATTGCAGGTATTGCGGACGAAGAACGTTCACTATACGGCGTGCAATTCCACCCAGAAGTACGTCACTCAGTTTACGGCAA
CGAATTACTGAAGAATTTTGCATTAAATGTTTGTGGCTGTAAAGGCGACTGGACAATGGAGAACTTTAGTGAAGTAGAAA
TTGCTAAAATCCAAGAAATCGTAGGCGACAAAAAAGTCTTGCTTGCCCTTTCTGGCGGTGTAGATTCCTCTGTTGTTGGT
GTGTTAATTCATAAAGCAATCGGCGACCAACTAACTTGTATTTTCGTAGACCATGGCCTTCTTCGCAAAGGGGAAGCTGA
CCAAGTAATGGCAACATTACAAGGCGAATTCAACATGAACATCATCAAAGTAGATGCGAAAAAACGCTTCATGGACAAAC
TTGCTGGCGTTTCTGACCCAGAGCAAAAACGTAAAATCATCGGTAACGAATTCATTTACGTATTCGACGATGAAGCTAAC
AAACTAGACGGCGTAGAATTCCTAGCTCAAGGAACACTTTACACAGACATCATCGAAAGTGGTACAGCAACTGCCCAAAC
AATCAAGTCTCACCACAATGTAGGCGGCTTACCAGAAGATATGCAATTTAAACTAATCGAACCATTAAATACACTTTTCA
AAGATGAAGTTCGCGCACTAGGAACAGAACTTGGCATGCCTGACGCAATCGTTTGGCGCCAACCATTCCCAGGCCCAGGC
TTAGGAATCCGCGTTCTTGGCGAAATTACGGAAGAGAAATTAGAGATTGTCCGCGATTCTGATTACATCTTGCGTGAAGA
AATCAAAAACGCAGGTCTAGAACGCGAAATCTGGCAATACTTTACTGCTCTTCCAAATATCCGTAGCGTTGGTGTTATGG
GTGATGGCAGAACGTATGACCATACTGTGGTTGTTCGTGCAGTGACGAGTATTGATGGTATGACAGCGGATTGGGCACGT
ATTCCGTGGGATGTACTGGAGAAAATTTCGGTACGGATTGTGAATGAAGTGGATCACGTGAATCGTGTTGTTTATGATAT
TACGAGTAAACCACCAGCTACGGTTGAGTGGGAGTAA

Protein sequence :
MFKIMKDFTEQEKIIVLDFGSQYNQLITRRIREFGVYSELHPHTITVEEMKALNPTGIIFSGGPNSVYDEDAFRADERIF
DMGIPILGICYGMQLMTTHFGGKVERAKDREYGKADIHVEKPNRLFAGLPTDQVVWMSHGDLVVEEPAGFEVTITSKSCP
IAGIADEERSLYGVQFHPEVRHSVYGNELLKNFALNVCGCKGDWTMENFSEVEIAKIQEIVGDKKVLLALSGGVDSSVVG
VLIHKAIGDQLTCIFVDHGLLRKGEADQVMATLQGEFNMNIIKVDAKKRFMDKLAGVSDPEQKRKIIGNEFIYVFDDEAN
KLDGVEFLAQGTLYTDIIESGTATAQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRALGTELGMPDAIVWRQPFPGPG
LGIRVLGEITEEKLEIVRDSDYILREEIKNAGLEREIWQYFTALPNIRSVGVMGDGRTYDHTVVVRAVTSIDGMTADWAR
IPWDVLEKISVRIVNEVDHVNRVVYDITSKPPATVEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 0.0 75
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 0.0 75
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 0.0 75
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-129 53