Gene Information

Name : thiC (ACP_2763)
Accession : YP_002755783.1
Strain : Acidobacterium capsulatum ATCC 51196
Genome accession: NC_012483
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 3218298 - 3219752 bp
Length : 1455 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGGCTTCCAATCCGACACTTGAGATTCTGAAACCCCGCGCTGAATGGATCGTAAAGCGCAAAGCCGAAGCCCTGCGCAC
GGGCGACACCAACATGTCGCAGATGCACTTTGCCCGCAAAGGGCTGATCACCGAGGAGATGGCCTACGTGGCCAAGCGCG
AGCAGATTTCGGTGGAACTGGTGCGCGACGAGATCGCGGCCGGGCGGCTGATTATTCCGGCGAACATCAATCACCCGGAG
CTGGAGCCGATGGCGATTGGCATCGCCTCAAAGTGCAAGGTGAATGCGAATATCGGCAACTCGGCCGTGACGTCGAATAT
CGATGAAGAGCTGCGCAAGCTGCATATGGCCGTGCAGTTTGGCGCCGATACGGTGATGGATTTATCGACGGGCGGGAATA
TTCCGGAGATTCGCGACGCCATTTTGCGGCACTCGCCGGTGCCGATTGGCACGGTGCCGATTTATGAGGCGCTGAACCGC
GTGAAGCGGCTCGAAGACCTGAACATCGACGTGTACCTGGAAGTGATTGAAGAGCAGGCCGAGCAGGGCGTGGATTATTT
CACGGTGCATGCGGGACTGCTGATTCAGTATGTGCCGATGGTGGCCAAGCGCATCACGGGCATTGTGAGCCGCGGCGGCG
CGATTCTGGCGCAGTGGATGACGCACCACCACAAGCAGAACTTCCTGTATGAGCACTTTGACCGCATTGTGAAGGTGATG
GCCAAGCACGATGTGAGCTTCTCGCTGGGCGATGGCCTGCGGCCGGGCAGTGTGGCCGATGCCGCCGACGAGGCGCAGTA
TGCCGAGCTGAAGACGCTGGGCGAGCTGACGGCGAAGGCCTGGCAGAGCGACGTGCAGGTGATGATCGAAGGGCCGGGGC
ATGTGCCGCTGGACAAGATCAAGGAGCAGGTGGACAAGGAAGTGGAGTACTGCTTTGGCGCGCCCTTCTACACGCTGGGG
CCGCTGGTGACCGACATTGCTCCCGGTTATGACCACATCACGTCGGCGATTGGCGCGGCGCTGATCGGCTGGCATGGCGC
CTCGATGCTCTGCTATGTGACGCCCAAGGAGCACCTGGGCCTGCCGAACGAGAAGGATGTGAAGGACGGCATGATTGCCT
ACAAGATTGCGGCGCATGCGGCCGACATTGCACGGCACCGGCCGGGCGCGCGCGACCGCGACGACGCTATCAGCTATGCC
CGTTACACCTTCGATTGGGAGAAGCAGTTCGCTCTCTCGATCGATCCGGAAACGGCGCGCAGCATGCACGATGAGACGCT
GCCGGATGACTACTACAAGGACGCGGCCTTCTGCTCGATGTGCGGGCCGAAGTTCTGCTCGATGAACTGGTCGAGCAAGG
TGGACGAGTTCAACAAGGAAGTCCACGGGCTCGAGAAGAAAGATCTCTCCGAACTGGTGACGCTGCAGGCGCAGCAGTTG
CAGACGAAGAGCTAG

Protein sequence :
MASNPTLEILKPRAEWIVKRKAEALRTGDTNMSQMHFARKGLITEEMAYVAKREQISVELVRDEIAAGRLIIPANINHPE
LEPMAIGIASKCKVNANIGNSAVTSNIDEELRKLHMAVQFGADTVMDLSTGGNIPEIRDAILRHSPVPIGTVPIYEALNR
VKRLEDLNIDVYLEVIEEQAEQGVDYFTVHAGLLIQYVPMVAKRITGIVSRGGAILAQWMTHHHKQNFLYEHFDRIVKVM
AKHDVSFSLGDGLRPGSVADAADEAQYAELKTLGELTAKAWQSDVQVMIEGPGHVPLDKIKEQVDKEVEYCFGAPFYTLG
PLVTDIAPGYDHITSAIGAALIGWHGASMLCYVTPKEHLGLPNEKDVKDGMIAYKIAAHAADIARHRPGARDRDDAISYA
RYTFDWEKQFALSIDPETARSMHDETLPDDYYKDAAFCSMCGPKFCSMNWSSKVDEFNKEVHGLEKKDLSELVTLQAQQL
QTKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 5e-129 62
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 5e-129 62
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 2e-123 59