Gene Information

Name : pyk (ACP_1882)
Accession : YP_002754951.1
Strain : Acidobacterium capsulatum ATCC 51196
Genome accession: NC_012483
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 2226108 - 2227625 bp
Length : 1518 bp
Strand : +
Note : identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064

DNA sequence :
ATGAATTTCACGTATGCCGGCAATGAGCCGGCTCACGAGCCGCGCCGCGCCAAGATTGTAGGCACGCTGGGACCCGCTTC
TTCGCACGCTGATGTTTTCCGCGAACTGGTTCGTGCCGGACTCGATGTGGCCCGGTTAAATTTTTCTCACGGTACGCATC
CTGAGAAGCTGAAGCTGATCGAGATGGTTCGCACCGTCGCCGCCGAAGAGAAGAAGACCATCTGCATTCTTGCCGACCTG
CAGGGTCCGAAGATTCGCACCGGAAGACTGCAGGACCGCATACCGGTGCAGTTGAAGGCCGGGCAGACTCTGACGATTAC
TCCGAAGGATATTGCCGGCACCGCCACAGTGATCGCCACCACCTTCCCGACGCTGGCCGAAAATCTGACGGAGGGAGATC
GCATCCTGCTCTCGGACGGCTTGATCGAGCTGCGCGTGAAGAGCATTCAGGGAGAAGACGTCGAATGCACCGTGATGAAC
GGCGGCACGCTCGGTGAGCACAAGGGCATTAATCTGCCCGGCATTCCGGTCAAGGTGCCTTCGCTCACGGAGAAGGACGA
TATTGATCTGGTCTTTGCCGTTCAGAACAATGTAGATGCCATTGCGCTCTCGTTTGTCCGCACGGCCGAAGACGTAAAGC
TGGTGAAGGATCGCATTGCGGCTCTGGGCTCAAGCACATGGGTGATTGCAAAGCTTGAAAAACCGCAGGCGATCGACAAT
CTGGAAGAGATTCTGGAAGCGGCTGATGGCATCATGGTGGCTCGCGGCGACCTTGGCGTGGAAGTTCCACCCGAGAAAGT
TCCGGCCATCCAGAAGCACATGATTCGCCGCGCGCGCGCCTGGCGCAAGCCGGTGATCACGGCAACGCAAATGCTGGAGT
CGATGATTGAGAATCCGCGCCCCACGCGCGCCGAGGCGAGCGACGTCGCCAATGCCGTCTATGACGGCACCGATGCGGTG
ATGCTCTCGGCTGAGACGGCCGCCGGCAAGTACCCGATTGAGGCCGTACACATGATGGCTCGGATTGCGTCCGAGACCGA
GAGCAACCTGGAGCACAGCGCGCAGGAAGCCCGGCCTCCGCATCAGCGGCTTTCGATTCCAGAGACAATCTGCGAATCGA
TGGCGCACGCGTGCGAGGATCTCGATGTGGCCGCCATTGCCGTCTTCACCGAGACCGGAACGACGGCACGCCAGCTCTCG
AAGTACCGGCCGAAACCCCCGATTTATGCGCTTTCGAGCGTGCCGGAGGTGATCAACCGCATGGCCATGCTCTGGGGCGT
AAAGCCGATCCTCTGCGAGAAGGCCTACACCACTGAAGATATGGTGGACACCGCCGAACGCCTCATGCAGGAGGGCGGCT
ATGCCAAGAAGCAGGACATTCTTGGCATTGTGGCCGGCACCCGCACCCGCAGCGGCTCGACCAACTTTCTGCGTCTGCAC
ATTATTGGCGACCGTGCTCCCGAAGTTACGGACGCAGCCAAGACCGCCGAACAGAAGCCGGAAACGGCGAAGGCTTAA

Protein sequence :
MNFTYAGNEPAHEPRRAKIVGTLGPASSHADVFRELVRAGLDVARLNFSHGTHPEKLKLIEMVRTVAAEEKKTICILADL
QGPKIRTGRLQDRIPVQLKAGQTLTITPKDIAGTATVIATTFPTLAENLTEGDRILLSDGLIELRVKSIQGEDVECTVMN
GGTLGEHKGINLPGIPVKVPSLTEKDDIDLVFAVQNNVDAIALSFVRTAEDVKLVKDRIAALGSSTWVIAKLEKPQAIDN
LEEILEAADGIMVARGDLGVEVPPEKVPAIQKHMIRRARAWRKPVITATQMLESMIENPRPTRAEASDVANAVYDGTDAV
MLSAETAAGKYPIEAVHMMARIASETESNLEHSAQEARPPHQRLSIPETICESMAHACEDLDVAAIAVFTETGTTARQLS
KYRPKPPIYALSSVPEVINRMAMLWGVKPILCEKAYTTEDMVDTAERLMQEGGYAKKQDILGIVAGTRTRSGSTNFLRLH
IIGDRAPEVTDAAKTAEQKPETAKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-84 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-84 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-84 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-84 42
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 4e-64 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_002754951.1 pyruvate kinase VFG0479 Protein 5e-85 43