Gene Information

Name : guaA (ACP_1114)
Accession : YP_002754219.1
Strain : Acidobacterium capsulatum ATCC 51196
Genome accession: NC_012483
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1281165 - 1282715 bp
Length : 1551 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGGAAACCTCCTCGATCGTCATCCTTGATTTTGGCTCTCAGTACACGCAGCTCATCGCGCGCCGTATTCGTGAGCAGAA
CGTCTTTTCTGTCGTGCTGCCATGCACGGCCTCGCTCGAAGAAGTGCAGGCACAGCGTCCACTCGGCATCATTCTGTCAG
GTGGTCCCTGCTCGGTCTACGACGCCGATGCGCCGCCGGCCGATCCGCGCGTGCTCGAGCTGGGCCTGCCGGTGCTCGGC
ATCTGCTATGGCTTGCAATTCATCACGCATCATCTTGGCGGCAAAGTTCGCTCGGCAGAGAAGCGCGAATACGGTCATGC
CGAGGTCATGGTAGAAGACGCAGGCAACGCGCTTTTCACGAATGTTCCTCCTTCGGTGAACGTGTGGATGTCGCACGGCG
ACGAGGCGCTCGAACTGCCGCCCGGATTTCATCGCACCGCGAAGACGGCAAATGCTGTCGCCGGCATTGCCAACCCCGAG
CGCCGCATTTGGGCCGTGCAGTTTCATCCTGAGGTCAAGCACACGGCGCACGGCACTGATCTGCTGCGCAACTTTGTCTT
CAACATCTGCGATGCGAAGCCGGAATGGACGCCGGAGCTCTTCATTCAGAGCACGGTGGCCGCCATTCGCGAAAAAGTTG
GCGATGGCCAGGCCATCTGCGCGCTCTCAGGCGGAGTAGATTCATCGGTGGCCGCAGTGCTGGTGCATCGCGCCATTGGC
GACCAGCTGACCTGCGTGTTCGTCGACAACGGGGTGTTGCGCCTGAATGAATTTGAGAAGGTGCAGCAAAACTTGCGCGG
CAAGCTCGGCCTGAACCTGGTAGCCGTGGATGCAAGCAAGCGCTTCCTCGATAAGCTGGCCGGCGTCACCGATCCGGAGG
CGAAGCGCAAGATCATCGGCAACGAGTTCATCGCGGTTTTTGACGATGAGGCGCACCGCATTGCGCAGCAGACCGGCGGC
GTGGACTGGCTGGTGCAGGGCACGCTCTATCCTGACGTGATTGAGTCTTCATCCGTCAAAGGTCCTTCGCAGACCATCAA
GAGCCATCACAACGTCGGTGGCCTGCCTGAGGATATGAAGCTCAAGTTGATTGAGCCGCTGCGCGATCTTTTCAAAGATG
AAGTCCGTCGCATCGGAGCCGATCTGGGCATGCCGCAGGACATTCTGCAGCGCCAGCCCTTTCCGGGGCCTGGTCTGGCT
GTGCGCATTCTCGGTGAAATTACGCCTGAGCGTGTCGCCCTGCTGCAGGAAGCCGATGACATCGTGGTGGACGAGATCAA
GAAGGCCGGTTTGTATCAGCAGATATGGCAATCCTTTGCCGTGCTGCTGCCGGTCAAAAGCGTGGGCGTCATGGGCGACC
AGCGCACCTATGCCTACACGTGTGCCATTCGTGCCGTCCACTCAGATGACGGCATGACAGCTGACTGGGTGCCGCTGCCC
TACGATGTGCTCAAGAAAATCTCCAGCCGCATCGTGAATGAAGTACGTGGCATCAACCGCGTCGTGTATGACATCACGTC
AAAGCCGCCCGGCACCATCGAGTGGGAGTAG

Protein sequence :
METSSIVILDFGSQYTQLIARRIREQNVFSVVLPCTASLEEVQAQRPLGIILSGGPCSVYDADAPPADPRVLELGLPVLG
ICYGLQFITHHLGGKVRSAEKREYGHAEVMVEDAGNALFTNVPPSVNVWMSHGDEALELPPGFHRTAKTANAVAGIANPE
RRIWAVQFHPEVKHTAHGTDLLRNFVFNICDAKPEWTPELFIQSTVAAIREKVGDGQAICALSGGVDSSVAAVLVHRAIG
DQLTCVFVDNGVLRLNEFEKVQQNLRGKLGLNLVAVDASKRFLDKLAGVTDPEAKRKIIGNEFIAVFDDEAHRIAQQTGG
VDWLVQGTLYPDVIESSSVKGPSQTIKSHHNVGGLPEDMKLKLIEPLRDLFKDEVRRIGADLGMPQDILQRQPFPGPGLA
VRILGEITPERVALLQEADDIVVDEIKKAGLYQQIWQSFAVLLPVKSVGVMGDQRTYAYTCAIRAVHSDDGMTADWVPLP
YDVLKKISSRIVNEVRGINRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-138 56
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-138 56
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-138 56
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-133 54