Gene Information

Name : sph (BCA_0714)
Accession : YP_002748032.1
Strain : Bacillus cereus 03BB102
Genome accession: NC_012472
Putative virulence/resistance : Virulence
Product : sphingomyelin phosphodiesterase C
Function : -
COG functional category : R : General function prediction only
COG ID : COG3568
EC number : 3.1.4.12
Position : 684500 - 685501 bp
Length : 1002 bp
Strand : +
Note : identified by match to protein family HMM PF03372; match to protein family HMM TIGR03395

DNA sequence :
GTGAAAGGTAAATTGTTAAAAGGTGTACTTAGCTTTGGGATTGGTTTAGGAGTTTTATACGGAGGATCTTCAGCTCAAGC
AGATACGTCTACAGATCAAAACAACATTTTGAAAGTGATGACGCATAATGTGTACATGCTATCAACTAACTTATATCCGA
ATTGGGGACAAAGTGAGCGTGCTGATTTAATTGGGGCGGCAGATTATATTAAGAATCAAGACGTTGTTATATTAAATGAA
GTGTTTGATAATAGTGCTTCAGATCGCCTTTTAGGAAATTTGAAGAAAGAATACCCAAATCAAACAGCTGTATTAGGTCG
TAGTAACGGAAATGAATGGGATAAAACGTTAGGTAGCTATTCATCTGCAACTCCTGAAGATGGGGGCGTTGCAATCGTGA
GCAAATGGCCGATCGTTGAAAAGGTTCAATATGTATTTGCAAATGGATGCGGACCAGATAATTTATCGAATAAAGGATTT
GTATACACGAAAATTAAGAAAAATGATCGTTTCGTTCATGTAATTGGGACGCATTTGCAGGCTGAAGATAGTATGTGCGG
AAAAACTTCACCTGCATCTGTACGTACAAACCAGTTAAAAGAAATTCAAGATTTTATTAAAAATAAAAATATACCAAATG
ACGAGTACGTTCTATTTGGTGGTGATATGAATGTGAATAAAATAAACGCTGAGAACAATAGTGACTCAGAGTACGCATCC
ATGTTCAAAACATTACATGCTTCTATTCCATCTTATACAGGACATACAGCAACTTGGGATGCGACGACAAACAGTATTGC
AAAATATAATTTCCCTGATAGCCCTGCCGAGTATTTAGATTATATTATTGCAAGTAAGGACCATGCGAATCCGTCATTTA
TAGAGAATAAAGTATTACAACCGAAATCTCCACAGTGGACTGTTACATCATGGCTCAAAAAATATACATATAATGATTAC
TCTGATCATTATCCAGTCGAGGCGACTATTTCTATGAAGTAG

Protein sequence :
MKGKLLKGVLSFGIGLGVLYGGSSAQADTSTDQNNILKVMTHNVYMLSTNLYPNWGQSERADLIGAADYIKNQDVVILNE
VFDNSASDRLLGNLKKEYPNQTAVLGRSNGNEWDKTLGSYSSATPEDGGVAIVSKWPIVEKVQYVFANGCGPDNLSNKGF
VYTKIKKNDRFVHVIGTHLQAEDSMCGKTSPASVRTNQLKEIQDFIKNKNIPNDEYVLFGGDMNVNKINAENNSDSEYAS
MFKTLHASIPSYTGHTATWDATTNSIAKYNFPDSPAEYLDYIIASKDHANPSFIENKVLQPKSPQWTVTSWLKKYTYNDY
SDHYPVEATISMK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hlb NP_646757.1 truncated beta-hemplysin Not tested ¥ÕSa3 Protein 8e-71 59
hlb NP_375112.1 hypothetical protein Not tested ¥ÕSa3 Protein 9e-71 59
truncated-hlb NP_372527.1 hypothetical protein Not tested ¥ÕSa3 Protein 6e-71 59
unnamed CAA70683.2 sphingomyelinase-c Virulence LIPI-2 Protein 1e-76 55

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sph YP_002748032.1 sphingomyelin phosphodiesterase C VFG1798 Protein 3e-78 58
sph YP_002748032.1 sphingomyelin phosphodiesterase C VFG0674 Protein 7e-77 55