Gene Information

Name : bla1 (BCA_2591)
Accession : YP_002749864.1
Strain : Bacillus cereus 03BB102
Genome accession: NC_012472
Putative virulence/resistance : Resistance
Product : beta-lactamase Bla1
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG2367
EC number : 3.5.2.6
Position : 2410501 - 2411331 bp
Length : 831 bp
Strand : +
Note : identified by match to protein family HMM PF00144

DNA sequence : 
TTGCAAGTTGAAGCGAAAGAAAAGAAAGGGCAAATAAAACATAAAAATCAGGCGACGCATAAAGAGTTCTCTCAACTTGA
GAAAAAATTTGATGCTCGATTAGGTGTATATGCGATTAATACTGGTACAAAACAAACAATCGCTTATCGACCTAACGAAA
GGTTTGCTTTTGCATCAACTTACAAGGCTTTAGCGGCAGGAGTATTACTGCAGCAAAACTCTACTATGAAATTAGATGAA
GTTATTACTTATACGAAAGAAGACTTAGTGGATTATTCACCTGTTACAGAGAAACATGTAGATACTGGAATGACACTAGG
AGAAATTGCGGAGGCTGCTGTTCGTTACAGTGATAATACTGCAGGGAACATTTTATTTAACAAAATAGGCGGACCAAAAG
GATATGAAAAAGCGCTTAGACAGATGGGTGATCGTGTTACTATGTCTGATCGCTTTGAAACAGAATTAAACGAGGCTATT
CCAGGAGACATTCGTGACACTAGTACAGCGAAAGCAATTGCTACGAATCTTAAAGCTTTTACGGCCGGAAATGCACTTCC
AAATCATAAGCGTAACATTCTTACAGAGTGGATGAAAGGAAATGCTACAGGAGACAAACTTATTCGTGCAGGTGTACCAA
CCGACTGGATAGTTGCAGATAAATCAGGGGCTGGAAGTTATGGGACACGAAATGATATCGCTATCGTTTGGCCGCCAAAT
AGAGCACCAATTATCATCGCAATTTTATCTAGTAAAGATGAGAAAGAGGCTACCTATGATAATCAACTTATTGCAGAGGC
GGCTGAAGTTATAGTTAATGCTTTTAGGTGA

Protein sequence : 
MQVEAKEKKGQIKHKNQATHKEFSQLEKKFDARLGVYAINTGTKQTIAYRPNERFAFASTYKALAAGVLLQQNSTMKLDE
VITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGPKGYEKALRQMGDRVTMSDRFETELNEAI
PGDIRDTSTAKAIATNLKAFTAGNALPNHKRNILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPN
RAPIIIAILSSKDEKEATYDNQLIAEAAEVIVNAFR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
blaCTX-M2 ACF06162.1 beta-lactamase CTX-M2 Not tested Tn5036-like Protein 2e-50 43
pse-1 AGK07108.1 PSE-1 beta-lactamase Not tested SGI1 Protein 7e-41 41
pse-1 AAK02055.1 beta-lactamase Not tested SGI1 Protein 7e-41 41
pse-1 AGK06978.1 PSE-1 beta-lactamase Not tested SGI1 Protein 7e-41 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
bla1 YP_002749864.1 beta-lactamase Bla1 AF367983.gene.p01 Protein 4e-123 97
bla1 YP_002749864.1 beta-lactamase Bla1 EU729727.1.gene1.p1 Protein 4e-53 47
bla1 YP_002749864.1 beta-lactamase Bla1 AY034847.1.gene1.p01 Protein 7e-52 47
bla1 YP_002749864.1 beta-lactamase Bla1 HM066995.1.gene1.p01 Protein 2e-51 47
bla1 YP_002749864.1 beta-lactamase Bla1 EU555534.1.gene1.p01 Protein 4e-52 47
bla1 YP_002749864.1 beta-lactamase Bla1 AF275256.gene.p01 Protein 4e-53 46
bla1 YP_002749864.1 beta-lactamase Bla1 AF395881.gene.p01 Protein 8e-53 46
bla1 YP_002749864.1 beta-lactamase Bla1 GQ140348.1.gene1.p01 Protein 1e-52 46
bla1 YP_002749864.1 beta-lactamase Bla1 FJ234412.1.gene1.p01 Protein 4e-53 46
bla1 YP_002749864.1 beta-lactamase Bla1 DQ663489.gene.p01 Protein 9e-49 46
bla1 YP_002749864.1 beta-lactamase Bla1 AF297554.1.gene1.p1 Protein 2e-51 46
bla1 YP_002749864.1 beta-lactamase Bla1 DQ328639.gene.p01 Protein 8e-49 46
bla1 YP_002749864.1 beta-lactamase Bla1 HQ641421.1.gene1.p01 Protein 1e-51 46
bla1 YP_002749864.1 beta-lactamase Bla1 AF135373.1.gene1.p01 Protein 3e-47 46
bla1 YP_002749864.1 beta-lactamase Bla1 Z28968.gene.p01 Protein 2e-51 45
bla1 YP_002749864.1 beta-lactamase Bla1 U50278.1.gene2.p01 Protein 2e-54 45
bla1 YP_002749864.1 beta-lactamase Bla1 AY178993.1.gene1.p01 Protein 3e-47 45
bla1 YP_002749864.1 beta-lactamase Bla1 AY005110.1.gene1.p1 Protein 3e-47 45
bla1 YP_002749864.1 beta-lactamase Bla1 GQ149243.1.gene1.p01 Protein 5e-51 44
bla1 YP_002749864.1 beta-lactamase Bla1 U95364.1.gene1.p01 Protein 4e-50 44
bla1 YP_002749864.1 beta-lactamase Bla1 HM776707.1.gene1.p1 Protein 1e-50 44
bla1 YP_002749864.1 beta-lactamase Bla1 DQ102702.1.gene1.p1 Protein 1e-50 44
bla1 YP_002749864.1 beta-lactamase Bla1 EF581888.1.gene1.p01 Protein 2e-50 44
bla1 YP_002749864.1 beta-lactamase Bla1 AB284167.2.gene1.p01 Protein 8e-51 44
bla1 YP_002749864.1 beta-lactamase Bla1 EF374097.1.gene1.p01 Protein 8e-51 43
bla1 YP_002749864.1 beta-lactamase Bla1 DQ125241.gene.p01 Protein 1e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 AJ416344.1.gene1.p01 Protein 2e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 DQ408762.1.gene1.p1 Protein 1e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 GU127598.1.gene1.p1 Protein 9e-51 43
bla1 YP_002749864.1 beta-lactamase Bla1 GQ149244.1.gene1.p01 Protein 8e-51 43
bla1 YP_002749864.1 beta-lactamase Bla1 X92507.1.gene1.p01 Protein 1e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 AJ567481.1.gene1.p01 Protein 1e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 Y14156.1.gene1.p01 Protein 3e-48 43
bla1 YP_002749864.1 beta-lactamase Bla1 AY750914.gene.p01 Protein 3e-48 43
bla1 YP_002749864.1 beta-lactamase Bla1 AB205197.1.gene1.p01 Protein 3e-48 43
bla1 YP_002749864.1 beta-lactamase Bla1 FJ907381.1.gene1.p01 Protein 4e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 AY847145.1.gene1.p01 Protein 9e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 JF274247.1.gene1.p01 Protein 6e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 FJ214369.1.gene1.p1 Protein 2e-49 43
bla1 YP_002749864.1 beta-lactamase Bla1 AY847144.1.gene1.p01 Protein 2e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 AY157676.1.gene1.p01 Protein 4e-48 43
bla1 YP_002749864.1 beta-lactamase Bla1 FJ971899.1.gene1.p1 Protein 2e-47 43
bla1 YP_002749864.1 beta-lactamase Bla1 JF274246.1.gene1.p01 Protein 2e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 EU136031.3.gene1.p3 Protein 2e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 HM803271.1.gene1.p01 Protein 3e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 AF518567.2.gene4.p01 Protein 2e-47 43
bla1 YP_002749864.1 beta-lactamase Bla1 AF325133.1.gene1.p1 Protein 2e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 AY029068.1.gene1.p1 Protein 5e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 AF325134.1.gene1.p1 Protein 1e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 HM755448.1.gene1.p01 Protein 3e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 DQ211987.1.gene1.p01 Protein 1e-49 43
bla1 YP_002749864.1 beta-lactamase Bla1 AY954516.1.gene1.p1 Protein 1e-47 43
bla1 YP_002749864.1 beta-lactamase Bla1 HQ833652.1.gene1.p01 Protein 2e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 HQ166709.1.gene1.p01 Protein 1e-49 43
bla1 YP_002749864.1 beta-lactamase Bla1 HQ398215.1.gene1.p01 Protein 1e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 AY033516.1.gene2.p01 Protein 2e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 AF174129.3.gene9.p01 Protein 6e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 JF274243.1.gene1.p01 Protein 1e-49 43
bla1 YP_002749864.1 beta-lactamase Bla1 HM167760.1.gene1.p01 Protein 1e-48 43
bla1 YP_002749864.1 beta-lactamase Bla1 FJ214367.1.gene1.p1 Protein 2e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 AY847146.1.gene1.p01 Protein 3e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 EU545409.1.gene1.p1 Protein 8e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 FJ214368.1.gene1.p1 Protein 2e-49 43
bla1 YP_002749864.1 beta-lactamase Bla1 AM982522.2.gene1.p01 Protein 5e-48 43
bla1 YP_002749864.1 beta-lactamase Bla1 AY847147.1.gene1.p01 Protein 2e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 AJ416345.gene.p01 Protein 6e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 AF189721.1.gene1.p01 Protein 9e-49 43
bla1 YP_002749864.1 beta-lactamase Bla1 AY156923.1.gene1.p01 Protein 2e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 AF252623.2.gene1.p01 Protein 3e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 GQ870432.1.gene1.p1 Protein 2e-47 43
bla1 YP_002749864.1 beta-lactamase Bla1 AF252622.2.gene2.p01 Protein 2e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 AY847143.1.gene1.p01 Protein 5e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 AY822595.1.gene1.p01 Protein 3e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 EF418608.1.gene1.p01 Protein 7e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 DQ023162.1.gene1.p1 Protein 1e-47 43
bla1 YP_002749864.1 beta-lactamase Bla1 HQ833651.1.gene1.p01 Protein 2e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 AY143430.1.gene1.p01 Protein 4e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 FJ214366.1.gene1.p1 Protein 2e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 HQ913565.1.gene1.p01 Protein 3e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 JF274242.1.gene1.p01 Protein 1e-49 43
bla1 YP_002749864.1 beta-lactamase Bla1 AY238472.1.gene1.p01 Protein 8e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 X92506.gene.p01 Protein 1e-49 43
bla1 YP_002749864.1 beta-lactamase Bla1 EF210159.1.gene1.p01 Protein 6e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 AY292654.1.gene1.p1 Protein 1e-49 43
bla1 YP_002749864.1 beta-lactamase Bla1 AB177384.1.gene1.p01 Protein 7e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 AJ549244.1.gene1.p01 Protein 1e-49 43
bla1 YP_002749864.1 beta-lactamase Bla1 AY267213.1.gene1.p01 Protein 7e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 DQ061159.1.gene1.p01 Protein 7e-50 43
bla1 YP_002749864.1 beta-lactamase Bla1 AY080894.1.gene1.p01 Protein 2e-49 43
bla1 YP_002749864.1 beta-lactamase Bla1 AJ557142.gene.p01 Protein 1e-49 43
bla1 YP_002749864.1 beta-lactamase Bla1 AF488377.1.gene1.p1 Protein 1e-49 43
bla1 YP_002749864.1 beta-lactamase Bla1 AY037780.1.gene1.p01 Protein 4e-41 43
bla1 YP_002749864.1 beta-lactamase Bla1 AY303807.gene.p01 Protein 2e-48 42
bla1 YP_002749864.1 beta-lactamase Bla1 AJ005045.gene.p01 Protein 8e-48 42
bla1 YP_002749864.1 beta-lactamase Bla1 AY598759.gene.p01 Protein 3e-49 42
bla1 YP_002749864.1 beta-lactamase Bla1 EU177100.1.gene1.p01 Protein 1e-49 42
bla1 YP_002749864.1 beta-lactamase Bla1 AY515297.1.gene1.p1 Protein 1e-48 42
bla1 YP_002749864.1 beta-lactamase Bla1 DQ810789.1.gene1.p01 Protein 2e-49 42
bla1 YP_002749864.1 beta-lactamase Bla1 DQ256091.1.gene1.p1 Protein 2e-49 42
bla1 YP_002749864.1 beta-lactamase Bla1 GQ351346.1.gene1.p01 Protein 1e-49 42
bla1 YP_002749864.1 beta-lactamase Bla1 HQ398214.1.gene1.p01 Protein 2e-49 42
bla1 YP_002749864.1 beta-lactamase Bla1 EF219142.1.gene1.p01 Protein 2e-49 42
bla1 YP_002749864.1 beta-lactamase Bla1 FJ815436.1.gene1.p01 Protein 6e-49 42
bla1 YP_002749864.1 beta-lactamase Bla1 AM411407.1.gene1.p01 Protein 2e-49 42
bla1 YP_002749864.1 beta-lactamase Bla1 AJ704396.1.gene1.p01 Protein 1e-49 42
bla1 YP_002749864.1 beta-lactamase Bla1 AF255298.1.gene1.p1 Protein 3e-49 42
bla1 YP_002749864.1 beta-lactamase Bla1 DQ223685.1.gene1.p01 Protein 2e-49 42
bla1 YP_002749864.1 beta-lactamase Bla1 AF305837.gene.p01 Protein 1e-49 42
bla1 YP_002749864.1 beta-lactamase Bla1 EU402393.1.gene1.p1 Protein 1e-49 42
bla1 YP_002749864.1 beta-lactamase Bla1 Y10278.1.gene1.p01 Protein 2e-49 42
bla1 YP_002749864.1 beta-lactamase Bla1 AY995206.gene.p01 Protein 1e-49 42
bla1 YP_002749864.1 beta-lactamase Bla1 DQ885477.1.gene1.p01 Protein 2e-49 42
bla1 YP_002749864.1 beta-lactamase Bla1 DQ268764.2.gene6.p01 Protein 1e-49 42
bla1 YP_002749864.1 beta-lactamase Bla1 JF966749.1.gene1.p01 Protein 2e-49 42
bla1 YP_002749864.1 beta-lactamase Bla1 EU202673.2.gene1.p2 Protein 2e-49 42
bla1 YP_002749864.1 beta-lactamase Bla1 JN227085.1.gene1.p01 Protein 5e-49 42
bla1 YP_002749864.1 beta-lactamase Bla1 FJ873739.1.gene1.p01 Protein 6e-50 42
bla1 YP_002749864.1 beta-lactamase Bla1 EF426798.1.gene1.p1 Protein 2e-49 42
bla1 YP_002749864.1 beta-lactamase Bla1 AY847148.1.gene1.p01 Protein 2e-48 42
bla1 YP_002749864.1 beta-lactamase Bla1 AM176553.2.gene1.p01 Protein 1e-40 42
bla1 YP_002749864.1 beta-lactamase Bla1 EU032604.1.gene1.p01 Protein 1e-40 42
bla1 YP_002749864.1 beta-lactamase Bla1 FJ668814.gene1.p01 Protein 3e-40 42
bla1 YP_002749864.1 beta-lactamase Bla1 AM176558.2.gene1.p01 Protein 2e-40 42
bla1 YP_002749864.1 beta-lactamase Bla1 AM176550.2.gene1.p01 Protein 2e-40 42
bla1 YP_002749864.1 beta-lactamase Bla1 JN051143.1.gene1.p01 Protein 1e-40 42
bla1 YP_002749864.1 beta-lactamase Bla1 AF148850.1.gene1.p01 Protein 3e-40 42
bla1 YP_002749864.1 beta-lactamase Bla1 JF812965.1.gene1.p01 Protein 3e-40 42
bla1 YP_002749864.1 beta-lactamase Bla1 AF535129.1.gene1.p01 Protein 1e-39 42
bla1 YP_002749864.1 beta-lactamase Bla1 AF299299.1.gene1.p01 Protein 2e-40 42
bla1 YP_002749864.1 beta-lactamase Bla1 U14748.1.gene2.p01 Protein 4e-46 42
bla1 YP_002749864.1 beta-lactamase Bla1 NC_010066.5774791.p0 Protein 2e-43 41
bla1 YP_002749864.1 beta-lactamase Bla1 NC_003140.1122765.p0 Protein 2e-45 41
bla1 YP_002749864.1 beta-lactamase Bla1 NC_010063.5774822.p0 Protein 2e-45 41
bla1 YP_002749864.1 beta-lactamase Bla1 NC_005951.2853409.p0 Protein 2e-45 41
bla1 YP_002749864.1 beta-lactamase Bla1 NC_007931.3978604.p0 Protein 2e-45 41
bla1 YP_002749864.1 beta-lactamase Bla1 NC_005011.2598316.p0 Protein 2e-45 41
bla1 YP_002749864.1 beta-lactamase Bla1 AY649755.1.gene1.p01 Protein 1e-49 41
bla1 YP_002749864.1 beta-lactamase Bla1 AM176552.2.gene1.p01 Protein 7e-41 41
bla1 YP_002749864.1 beta-lactamase Bla1 AF313471.1.gene2.p01 Protein 4e-41 41
bla1 YP_002749864.1 beta-lactamase Bla1 AY008290.1.gene1.p1 Protein 4e-41 41
bla1 YP_002749864.1 beta-lactamase Bla1 AM176548.2.gene1.p01 Protein 4e-40 41
bla1 YP_002749864.1 beta-lactamase Bla1 U92041.1.gene1.p01 Protein 4e-40 41
bla1 YP_002749864.1 beta-lactamase Bla1 AM176547.2.gene1.p01 Protein 8e-40 41
bla1 YP_002749864.1 beta-lactamase Bla1 AY288915.1.gene1.p01 Protein 4e-40 41
bla1 YP_002749864.1 beta-lactamase Bla1 X55640.1.gene1.p01 Protein 7e-40 41
bla1 YP_002749864.1 beta-lactamase Bla1 AF226622.1.gene1.p01 Protein 2e-39 41
bla1 YP_002749864.1 beta-lactamase Bla1 HQ661363.1.gene1.p1 Protein 7e-40 41
bla1 YP_002749864.1 beta-lactamase Bla1 JX268631.1.gene1.p01 Protein 1e-39 41
bla1 YP_002749864.1 beta-lactamase Bla1 AF293345.1.gene1.p01 Protein 9e-40 41
bla1 YP_002749864.1 beta-lactamase Bla1 EU342351.1.gene1.p01 Protein 4e-40 41
bla1 YP_002749864.1 beta-lactamase Bla1 AY518560.gene.p01 Protein 7e-40 41
bla1 YP_002749864.1 beta-lactamase Bla1 AF547625.1.gene1.p1 Protein 2e-39 41
bla1 YP_002749864.1 beta-lactamase Bla1 AF148851.1.gene1.p01 Protein 7e-40 41
bla1 YP_002749864.1 beta-lactamase Bla1 DQ054528.1.gene1.p01 Protein 6e-40 41
bla1 YP_002749864.1 beta-lactamase Bla1 AY210887.1.gene1.p1 Protein 9e-40 41
bla1 YP_002749864.1 beta-lactamase Bla1 AB126603.gene.p01 Protein 9e-41 41