Gene Information

Name : BCA_0110 (BCA_0110)
Accession : YP_002747512.1
Strain : Bacillus cereus 03BB102
Genome accession: NC_012472
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence ClpC/MecB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 95296 - 97731 bp
Length : 2436 bp
Strand : +
Note : identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728

DNA sequence :
ATGATGTTTGGAAGATTTACAGAAAGAGCACAGAAAGTATTAGCTTTATCTCAAGAGGAAGCGATTCGTATTGGGCATAA
CAATATTGGAACAGAACATATTTTACTTGGGCTTGTACGCGAAGGTGAAGGAATTGCAGCAAAAGCGTTGATTGCTCTTG
GATTAAGTCCAGAGAAGGTTCAAAAAGAAGTAGAAGCGTTAATCGGACGCGGAACAGAAGCTTCTCAAACTGTACATTAT
ACACCGCGTGCTAAAAAGGTTATTGAGCTGTCTATGGATGAAGCTCGTAAATTAGGTCATTCTTACGTTGGAACAGAACA
TATTTTACTTGGTTTAATCCGCGAAGGTGAAGGGGTAGCGGCACGCGTTTTAAATAACTTAGGTGTTAGCCTAAATAAGG
CAAGACAACAAGTATTGCAACTTCTTGGAAGTAATGAAGCAAGTTCAGGTCACCAAGGTGGTTCTTCAACAAATGCAAAT
ACACCAACACTTGATAGCTTAGCACGTGATTTAACAGTTGTTGCACGTGAAAATCGTTTAGACCCTGTTATTGGACGTGG
TAAAGAAATTCAACGTGTAATTGAAGTTTTAAGCCGTAGAACAAAAAACAATCCTGTATTAATCGGGGAGCCTGGTGTAG
GTAAAACGGCAATTGCGGAAGGATTAGCACAACAAATCGTAAATAATGAAGTTCCTGAAACTTTACGAGATAAGCGTGTT
ATGACACTAGATATGGGTACAGTGGTAGCTGGAACGAAATACCGTGGTGAATTTGAAGACCGTTTGAAGAAAGTAATGGA
TGAAATTCGCCAAGCGGGAAATATCATTCTATTTATTGATGAACTTCATACATTAATCGGTGCAGGTGGAGCAGAAGGTG
CTATTGACGCATCGAATATTTTAAAACCATCTTTAGCTCGTGGGGAATTACAATGTATCGGGGCGACAACGTTAGATGAA
TATCGCAAATATATTGAAAAAGACGCAGCTTTAGAGAGACGTTTCCAACCAATTCACGTTGATGAGCCAAGTTTAGATGA
ATCAACTCAAATTTTGAAAGGTTTACGCGATCGTTATGAGGCACATCACCGCGTATCTATTACAGATGATGCAATTGATG
CAGCTGTAAAGCTTTCAGATCGTTATATTACAGATCGTTTCTTACCAGATAAAGCAATTGATTTAATTGATGAAGCTGCT
TCAAAGGTTCGCTTACGCTCTTATACAACACCACCAAATCTAAAAGAGCTTGAAGTGAAGCTTGAGGAAATTAGAAAAGA
AAAAGATGCAGCTGTACAAAGTCAAGAGTTTGAAAAAGCTGCTTCCTTACGTGATATGGAACAACGTTTACGCGAGAAGT
TAGAAGATACGAAGCGTCAATGGAAAGAACAACAAGGAAAAGAAAACTCAGAAGTGACAGTAGAAGATATTGCAAATGTT
GTTTCTACATGGACTCGTATCCCGGTTTCTAAACTTGCACAAACAGAGACTGATAAATTATTAAACTTAGAATCCATCCT
TCACGATCGTGTTATTGGTCAAGATGAAGCGGTAGTAGCTGTAGCGAAAGCTGTTCGCCGTGCTAGAGCAGGATTGAAAG
ATCCGAAACGTCCGATTGGGTCATTTATTTTCTTAGGGCCAACAGGTGTAGGTAAAACGGAGCTAGCAAGAGCGTTAGCA
GAATCTATGTTCGGTGATGAAGATGCAATGATTCGCATCGATATGTCTGAGTACATGGAGAAGCATTCTACTTCTCGTTT
AGTTGGGTCTCCTCCAGGGTATGTTGGATATGAAGAAGGTGGACAATTAACAGAAAAGGTTCGCCGTAAGCCATATTCAG
TTGTCCTATTAGACGAAGTAGAGAAAGCTCATCCTGATGTGTTTAACATTTTACTACAAGTATTAGAAGATGGTCGCTTA
ACAGATTCGAAAGGGCGTACGGTTGATTTCCGCAATACAATTGTTATTATGACATCTAACGTTGGTGCAGAGGCGTTAAA
ACGTAATAAGCATCTTGGATTTAACGTACAAGATGAGAGTCGCGATTATTCGGATATGAAAGGTAAAGTAATGGATGAGC
TGAAAAAAGCCTTCCGTCCAGAATTCTTAAACCGTATTGATGAAATTATCGTGTTCCATATGCTTGAGAAAAAACATATT
CAAGAGATTGTAACACTTATGGTAAATCAGTTAGTAAATCGCTTAAAAGAGCAAGAAATTGAATTGCATTTAACAGAAGG
AGCAATTTCGGCTATTGCTGATAAAGGGTTTGACCGAGAGTACGGTGCTCGCCCGCTTCGTAGAGCGATTCAGAAACATG
TAGAAGATAGACTATCTGAAGAACTGTTAAAAGGTGCTATTGAGAAAGGACAGAAAGTTATCTTTGATGTTGAAGGAGAA
TCATTTGTCATTCATAGTGCCGAAAAGGTAAAATAA

Protein sequence :
MMFGRFTERAQKVLALSQEEAIRIGHNNIGTEHILLGLVREGEGIAAKALIALGLSPEKVQKEVEALIGRGTEASQTVHY
TPRAKKVIELSMDEARKLGHSYVGTEHILLGLIREGEGVAARVLNNLGVSLNKARQQVLQLLGSNEASSGHQGGSSTNAN
TPTLDSLARDLTVVARENRLDPVIGRGKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIVNNEVPETLRDKRV
MTLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNIILFIDELHTLIGAGGAEGAIDASNILKPSLARGELQCIGATTLDE
YRKYIEKDAALERRFQPIHVDEPSLDESTQILKGLRDRYEAHHRVSITDDAIDAAVKLSDRYITDRFLPDKAIDLIDEAA
SKVRLRSYTTPPNLKELEVKLEEIRKEKDAAVQSQEFEKAASLRDMEQRLREKLEDTKRQWKEQQGKENSEVTVEDIANV
VSTWTRIPVSKLAQTETDKLLNLESILHDRVIGQDEAVVAVAKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALA
ESMFGDEDAMIRIDMSEYMEKHSTSRLVGSPPGYVGYEEGGQLTEKVRRKPYSVVLLDEVEKAHPDVFNILLQVLEDGRL
TDSKGRTVDFRNTIVIMTSNVGAEALKRNKHLGFNVQDESRDYSDMKGKVMDELKKAFRPEFLNRIDEIIVFHMLEKKHI
QEIVTLMVNQLVNRLKEQEIELHLTEGAISAIADKGFDREYGARPLRRAIQKHVEDRLSEELLKGAIEKGQKVIFDVEGE
SFVIHSAEKVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 58

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BCA_0110 YP_002747512.1 negative regulator of genetic competence ClpC/MecB VFG0079 Protein 0.0 77
BCA_0110 YP_002747512.1 negative regulator of genetic competence ClpC/MecB VFG0080 Protein 5e-148 52