Gene Information

Name : nrdF (SEQ_0886)
Accession : YP_002746218.1
Strain : Streptococcus equi 4047
Genome accession: NC_012471
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 857023 - 857982 bp
Length : 960 bp
Strand : -
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGACCACATACTATGAAGCAATCAACTGGAATGAAATCGAAGATGTCATTGACAAGTCAACCTGGGAAAAGCTGACGGA
GCAATTCTGGCTTGATACACGTATTCCACTATCAAATGACCTTGATGACTGGCGCAGATTATCTGCTGTTGAAAAGGATT
TAGTAGGTAAGGTCTTTGGCGGGCTAACCCTTCTTGATACGATGCAGTCTGAGTCAGGAGTCGAAGCCATTCGCAAGGAC
GTGCGCACCCCGCATGAAGAGGCAGTTCTTAACAATATCCAATTTATGGAGTCTGTCCATGCTAAATCCTACTCATCAAT
CTTTTCGACCCTAAACACCAAAAAAGAAATTGAAGACATTTTTGAGTGGACCAACAACAACGTATTTCTTCAAAATAAGG
CTAAGATAATCAACGACATTTATGAAAATGGCAGTGCCCTTCAAAAAAAGGTAGCCTCGACTTATCTCGAAACCTTTCTA
TTTTATTCTGGCTTTTTTACACCACTCTATTATCTGGGCAACAATAAGCTGGCTAATGTCGCTGAAATTATTAAGCTCAT
CATTCGTGATGAGTCCGTTCATGGCACTTATATCGGCTACAAGTTTCAGCTGGGCTTTAATGAGCTATCAGAGAGTGAGC
AAGAAAGCCTTCGTGACTGGATGTATGACCTGCTGTATCAGCTATATGAAAATGAAGAGCAATACACCAAGACCCTCTAT
GATGAGGTTGGCTGGACCGAGGAAGTGATGACCTTCCTACGCTACAACGCTAACAAGGCTTTGATGAACCTTGGTCAGGA
CCCTCTTTTTCCAGACACTGCCAATGATGTCAACCCAATCGTTATGAATGGTATTTCAACCGGCACGTCAAACCACGATT
TCTTCTCTCAAGTTGGTAATGGCTACCTTCTTGGTACTGTTGAAGCTATGACTGATGACGATTACAATTATGGGCTATAA

Protein sequence :
MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDWRRLSAVEKDLVGKVFGGLTLLDTMQSESGVEAIRKD
VRTPHEEAVLNNIQFMESVHAKSYSSIFSTLNTKKEIEDIFEWTNNNVFLQNKAKIINDIYENGSALQKKVASTYLETFL
FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELSESEQESLRDWMYDLLYQLYENEEQYTKTLY
DEVGWTEEVMTFLRYNANKALMNLGQDPLFPDTANDVNPIVMNGISTGTSNHDFFSQVGNGYLLGTVEAMTDDDYNYGL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 4e-74 50