Gene Information

Name : SEQ_0252 (SEQ_0252)
Accession : YP_002745662.1
Strain : Streptococcus equi 4047
Genome accession: NC_012471
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : 2.7.7.7
Position : 232731 - 235391 bp
Length : 2661 bp
Strand : +
Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair

DNA sequence :
GTGTGGTATAATAAAGGCATGGAAAACAAGAATAAATTACTTTTGATTGATGGCTCCTCAGTGGCCTTTCGTGCCTTTTT
TGCCCTCTATAACCAGATTGACCGCTTTAAAAATCACAGCGGTCTTCACACTAATGCGATTTATGGCTTTCATTTGATGC
TAGACCACATGATGAAGCGTGTTCAGCCGACGCATGTCTTGGTGGCCTTTGACGCGGGTAAAACAACCTTTCGGACAGAG
CTTTTTGCTGATTACAAGGCAGGACGTGCCAAGACCCCTGATGAATTTCGGGAGCAGTTTCCTTATATTCGTGATATGCT
GGGAGCGCTTGGTATTGCCTTTTATGAGCTAGAGCATTACGAGGCAGACGATATTATCGGAACGCTTGATAAAATGGCAG
AGCGTACAGAGATTCCTTTTGATGTGACTATTGTCAGTGGTGACAAGGATTTGATTCAGCTGACAGATGCAAATACCGTT
GTTGAGATTTCTAAAAAAGGAGTTGCTGAATTTGAAGAGTTTACCCCAGCCTACCTTATGGACAAAATGGGGCTTACGCC
AGAGCAATTCATTGACTTGAAAGCGCTCATGGGAGACAAGTCTGATAATATTCCAGGAGTGACCAAAATTGGGGAAAAAA
CAGGTCTAAAGCTCCTGCACGAATATGGAAGCTTGGAGGGGATTTACGAGCATATTGATAGCTTCAAGCCTTCAAAAATG
AAGGAAAACCTGCTTCATGATAAGGAGCAGGCCTTCCTCTCAAAGACACTTGCTACTATCAACACTAGCGCTCCGATTAC
GATTGGATTGGAGGATATTGTCTATCAGGGTCCAGATCTAGATCGCTTGTCACAATTTTATGATGAGATGGATTTTGTTC
AACTAAAAAATGCCTTAGCTAGTCAGTTGCCACAGGAGCCGGTAGCTGAGATTGCTTATCAGGAAGTTACTGACATAAGA
GCGGACATGTTTTCAGACGATACGGTGTTTTATTTTGAAGCTTTGAGGGATAATTATCACCGCGAGGAGCTGATTGGCTT
TGCTTGGGGCAACCAAGGCCAGATTTATGCTTCAGCAGATATTAGTCTCCTCACTACAAAGCTCTTTAAAAAGGTTCTTG
AGCAGCCGATTGCTACCTATGATTTTAAGCGCAGTAAGGTTCTGCTTAGTCATCTGGGGCTTGATTTGCCGGCTGCCAGC
TATGATGCCCGCTTAGCTAATTACCTCTTGTCAACTGTAGAGGACAATGAGATGGCTACTCTGGCACGTCTTTATACCAC
TATATCACTGGATACAGATGAGGTTGTCTATGGTAAGGGGGTCAAGCGTGCTGTGCCTGACAAGGCTGTTTTGTTAGGAC
ATCTGGCGCGTAAGGTTCAGGTCTTGCTGGATAGTAGACCAGTCATGCTTGATAAGCTGGCAGAGCATGAGCAGGCTGAT
CTCTACACTGACATTGAACTGCCGCTTGCCAATGTCCTTGCGAAAATGGAAATCGAAGGCATTGCTGTCAATCAAGATAG
CCTGCAGGAAATGGCAGAGCAAAATAAGGTGGTCATTGAGGAACTGACACAGGAAATCTATGAAATGGCTGGTGAGGTCT
TTAATATTAATTCTCCCAAGCAGCTAGGAGTGATACTCTTTGAGAAAATGCAGCTCCCTCTTCATTTGACAAAGAAAACC
AAGACAGGCTATTCAACGGCTGTTGATGTCTTGGAGCGCTTAGCGCCAATTGCGCCAATCGTGGCTAAGATCTTGGACTA
TCGTCAAATTACTAAGCTGCAATCAACCTATGTGATTGGACTGCAGGATTACATCATGGCTGATGGCAGGATCCACACCC
GCTATTTACAGGATTTAACCCAGACAGGCCGACTTTCCAGTGTTGATCCTAACCTGCAAAATATCCCGATTCGTCTGGAG
CAGGGGCGCTTGATTCGTAAGGCCTTTACTCCATCTCATGATGATGCTGTTTTGCTTAGCTCGGATTATTCGCAAATTGA
ATTGCGTGTTTTAGCACATATTTCAGGAGATGAGCATTTGATTGCTGCTTTTAAGGAGGGAGCGGATATCCATACCTCAA
CGGCAATGCGTGTCTTTGGCATTGAAAAGCCAGAGGACGTCACTGCCAATGATCGTCGGAATGCTAAGGCTGTTAACTTT
GGCATTGTGTATGGGATTTCTGACTTTGGCTTGTCTAATAACCTTGGAATTCCAAGAAAACAGGCCAAGGCTTATATTGA
CACCTACTTTGAGCGCTACCCTGGTATCAAGGCTTACATGGAAAGGGTTGTGCGTGAAGCCAAGGATAAGGGCTATGTTG
AGACGCTCTTTAAGCGCCGTCGTCAATTGCCAGATATCAATTCTCGTCAGTTCAACGTTCGCTCCTTTGCAGAGCGTACA
GCCATTAATTCGCCCATTCAAGGCAGTGCAGCCGATATTCTCAAAATTGCGATGATAAATCTTGACCAAGCCCTAGTAGC
TGGTGGCTTTGAGACCAAAATGCTGCTTCAGGTGCATGATGAGATTGTGCTTGAGGTGCCTAATCATGAGCTAGCGGCTG
TTAAAGCGCTGGTCAAAGAAACGATGGAATCAGCTGTCAGCCTGGCAGTTCCGCTGCGTGTAGACGAAAGTGCCGGCAAG
AGCTGGTATGAGGCCAAGTAG

Protein sequence :
MWYNKGMENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVQPTHVLVAFDAGKTTFRTE
LFADYKAGRAKTPDEFREQFPYIRDMLGALGIAFYELEHYEADDIIGTLDKMAERTEIPFDVTIVSGDKDLIQLTDANTV
VEISKKGVAEFEEFTPAYLMDKMGLTPEQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEYGSLEGIYEHIDSFKPSKM
KENLLHDKEQAFLSKTLATINTSAPITIGLEDIVYQGPDLDRLSQFYDEMDFVQLKNALASQLPQEPVAEIAYQEVTDIR
ADMFSDDTVFYFEALRDNYHREELIGFAWGNQGQIYASADISLLTTKLFKKVLEQPIATYDFKRSKVLLSHLGLDLPAAS
YDARLANYLLSTVEDNEMATLARLYTTISLDTDEVVYGKGVKRAVPDKAVLLGHLARKVQVLLDSRPVMLDKLAEHEQAD
LYTDIELPLANVLAKMEIEGIAVNQDSLQEMAEQNKVVIEELTQEIYEMAGEVFNINSPKQLGVILFEKMQLPLHLTKKT
KTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIMADGRIHTRYLQDLTQTGRLSSVDPNLQNIPIRLE
QGRLIRKAFTPSHDDAVLLSSDYSQIELRVLAHISGDEHLIAAFKEGADIHTSTAMRVFGIEKPEDVTANDRRNAKAVNF
GIVYGISDFGLSNNLGIPRKQAKAYIDTYFERYPGIKAYMERVVREAKDKGYVETLFKRRRQLPDINSRQFNVRSFAERT
AINSPIQGSAADILKIAMINLDQALVAGGFETKMLLQVHDEIVLEVPNHELAAVKALVKETMESAVSLAVPLRVDESAGK
SWYEAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 0.0 87