Gene Information

Name : lysS (SEQ_1525)
Accession : YP_002746783.1
Strain : Streptococcus equi 4047
Genome accession: NC_012471
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 1528596 - 1530089 bp
Length : 1494 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTCAAATCAACACATCGAAGAATTAAATGATCAACAAATTGTCCGTCGTGAAAAAATGGCAGCCTTAGCTGAGCAAGG
CATTGATCCATTTGGCAAACGCTTCGACCGAACAACTAATTCTGGTGAATTAAAGGAAAAATACTCAGACAAAACCAAAG
AGGATTTACAAGAGCTTCAAGCCACTGCGATTATTGCTGGTCGTCTGATGACCAAGCGTGGTAAAGGAAAGGTCGGCTTT
GCTCATCTTCAGGATCGCCAAGGGCAAATCCAAATCTATGTTCGTAAGGATTCAGTTGGTGATGACAACTATGACATTTT
CAAAAAAGCTGACCTTGGTGATTTTATCGGGGTCGAAGGCGACATTATGTGTACTGATATGGGTGAGTTGTCTATCAAGG
CCACAAAACTGACCCATCTATCCAAATCTCTACGTCCGCTACCAGAGAAATTTCATGGCTTAACTGATATCGAAACCATT
TATCGCAAGCGTCATCTGGATTTGATTTCAAACCGCAGCAGCTTTGAACGGTTCATCACACGTTCAAAAATGATTTCTGA
AATTCGTCGTTACCTCGATGGCCTTGGCTTTTTAGAAGTGGAGACACCTGTCCTTCATAATGAAGCTGGTGGTGCTGCTG
CTCGTCCCTTTATCACTCACCACAATGCACAAGATATCGATATGGTGCTTCGCATTGCACCAGAGCTGCATCTCAAGCGC
CTCATCGTCGGTGGCATGGAGCGTGTCTATGAAATTGGACGGATCTTTCGTAATGAAGGGATGGACGCTACACATAACCC
AGAATTTACCTCTATTGAGGTCTATGAAGCCTATGCAGACTATTTAGATATGATGACTCTAACTGAAGGAATCATTCAGC
ACGCTGCTAAAGCAGTCAAGGGAGAGGGACCAATTGATTATCAGGGGACTGAAATCAAGCTTCATGAACCATTCAGACGC
GTGCATATGGTTGATGCCATCAAGGAGGTAACTGGTATTGACTTCTGGCCTGAGATGACTTTTGAGGAAGCAACAGCTCT
TGCTAACGAAAAGCATGTGCCAGTTGAAAAGCATTTTACCTCTGTTGGTCATATCATCAATGCCTTCTTTGAGGCATTTG
TCGAGGACACCCTAATTCAGCCAACCTTTGTCTATGGGCACCCTGTAGAGGTTTCACCGCTTGCTAAGAAAAACCCTGAG
GACAGTCGCTTCACAGACCGCTTTGAGCTCTTTATCATGACAAAGGAATATGCTAATGCCTTTACCGAGCTAAATGATCC
AATTGATCAGCTGTCACGCTTTAAGGCACAGGCAGCAGCCAAGGAGCTTGGAGACGATGAAGCAACCGGTATTGACTACG
ACTTCGTTGAGGCTCTTGAATACGGTATGCCACCAACAGGCGGGCTTGGAATCGGTATTGACCGCCTCTGCATGCTGCTG
ACAAATACAACCACTATTCGCGATGTTTTGTTATTCCCAACAATGAAGCCATAA

Protein sequence :
MSNQHIEELNDQQIVRREKMAALAEQGIDPFGKRFDRTTNSGELKEKYSDKTKEDLQELQATAIIAGRLMTKRGKGKVGF
AHLQDRQGQIQIYVRKDSVGDDNYDIFKKADLGDFIGVEGDIMCTDMGELSIKATKLTHLSKSLRPLPEKFHGLTDIETI
YRKRHLDLISNRSSFERFITRSKMISEIRRYLDGLGFLEVETPVLHNEAGGAAARPFITHHNAQDIDMVLRIAPELHLKR
LIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYEAYADYLDMMTLTEGIIQHAAKAVKGEGPIDYQGTEIKLHEPFRR
VHMVDAIKEVTGIDFWPEMTFEEATALANEKHVPVEKHFTSVGHIINAFFEAFVEDTLIQPTFVYGHPVEVSPLAKKNPE
DSRFTDRFELFIMTKEYANAFTELNDPIDQLSRFKAQAAAKELGDDEATGIDYDFVEALEYGMPPTGGLGIGIDRLCMLL
TNTTTIRDVLLFPTMKP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 2e-104 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_002746783.1 lysyl-tRNA synthetase VFG1668 Protein 9e-105 48