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Name : guaA (SEQ_1182) Accession : YP_002746484.1 Strain : Streptococcus equi 4047 Genome accession: NC_012471 Putative virulence/resistance : Unknown Product : GMP synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0519 EC number : 6.3.5.2 Position : 1165042 - 1166604 bp Length : 1563 bp Strand : + Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway DNA sequence : ATGACTGAAATTTCAATGTTGAATGATATTCAAAAAATTATCGTTCTTGATTATGGTAGTCAGTACAATCAACTGATTGC AAGACGTATTCGGGAGTTTGGTGTTTTTTCTGAGCTCAAAAGCCATCACATCACTGCGCAAGAGCTTCGTGACATCAATC CAATCGGGATTGTCCTGTCTGGTGGGCCAAATTCTGTTTATGCAACTGATGCCTTTGGTATTGATCCTGAAATCTTTGAA TTAGGGATTCCAATTTTAGGGATTTGCTATGGCATGCAGCTAATCACACATACCTTAGGAGGTAAGGTAGTCCCAGCTGG TCAAGCAGGTCACCGAGAATATGGTCAATCATCATTACGTTTACGTTCTGCATCAGCATTATTTGCGGGCACTCCAGATG AGCAGCTTGTTTTGATGAGTCATGGTGATGCTGTTACAGAAATCCCAGAGGGCTTTCATCTTGTAGGAGATTCTAACGAT TGCCCTTACGCTGCTATGGAAAATACAAAAAAGAGGCTCTACGGTATCCAATTCCACCCAGAGGTAAGACACTCTGTCTA TGGTAATGATATTTTGAAGAACTTTGCTATCTCTATCTGTGGTGGACGTGGTGATTGGTCAATGGATAATTTTATTGACA TGCAAATTGCTAAAATTCGCGAAACAGTCGGAGATCGTAAGGTTTTGCTAGGTTTGTCTGGTGGTGTTGATTCTTCAGTT GTTGGTGTCCTTTTACAAAAAGCTATCGGAGATCAATTAACCTGTATCTTTGTTGACCATGGACTTCTTCGTAAAAATGA AGGTGACCAAGTTATGGAAATGCTTGGTGGAAGATTTGGTCTCAATATTATTCGTGTTGATGCCTCAAAGCGCTTTTTAG ATCTTCTTGCAGGCGTTGAGGATCCTGAGAAAAAACGTAAAATTATCGGTAATGAGTTTGTTTACGTCTTTGATGACGAG GCTAGCAAGCTTAAGGGCGTTGACTTCCTTGCACAAGGAACGCTTTACACAGACATCATTGAATCTGGAACAGAAACTGC TCAAACGATAAAATCTCACCACAATGTTGGTGGTCTGCCAGAGGATATGCAGTTTGAATTAATCGAACCCCTCAATACAC TCTTTAAGGATGAGGTTCGTGCTCTTGGTACGGCCCTTGGTATGCCAGATGAAGTCGTCTGGCGTCAGCCTTTCCCAGGC CCAGGCCTTGCCATTCGCGTCATGGGAGAGATCACAGCAGAAAAGCTTGAAACAGTTCGCGAGTCAGATGCTATCCTTCG AGAAGAAATTGCTAAAGCAGGACTTGAGCGTGATGTGTGGCAATATTTTACAGTTAACACAGGTGTTCGTTCCGTCGGAG TTATGGGAGATGGTCGCACCTATGACTATACCATCGCTATTCGTGCTATCACCTCAATTGATGGTATGACAGCAGACTTT GCCCAATTGCCTTGGGAAGTTCTAAAGAAAATCTCAGTTCGAATTGTCAATGAAGTCGACCACGTTAATCGCATTGTCTA CGACATCACCAGCAAACCACCAGCAACCGTTGAGTGGGAGTGA Protein sequence : MTEISMLNDIQKIIVLDYGSQYNQLIARRIREFGVFSELKSHHITAQELRDINPIGIVLSGGPNSVYATDAFGIDPEIFE LGIPILGICYGMQLITHTLGGKVVPAGQAGHREYGQSSLRLRSASALFAGTPDEQLVLMSHGDAVTEIPEGFHLVGDSND CPYAAMENTKKRLYGIQFHPEVRHSVYGNDILKNFAISICGGRGDWSMDNFIDMQIAKIRETVGDRKVLLGLSGGVDSSV VGVLLQKAIGDQLTCIFVDHGLLRKNEGDQVMEMLGGRFGLNIIRVDASKRFLDLLAGVEDPEKKRKIIGNEFVYVFDDE ASKLKGVDFLAQGTLYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTALGMPDEVVWRQPFPG PGLAIRVMGEITAEKLETVRESDAILREEIAKAGLERDVWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSIDGMTADF AQLPWEVLKKISVRIVNEVDHVNRIVYDITSKPPATVEWE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SAPIG0468 | YP_005733278.1 | GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) | Not tested | SAPI-S0385 | Protein | 5e-173 | 70 |
| SAMSHR1132_03620 | YP_005324884.1 | GMP synthase | Not tested | vSa¥á | Protein | 4e-173 | 70 |
| guaA | YP_001331415.1 | GMP synthase | Not tested | vSa¥á | Protein | 3e-173 | 70 |
| guaA | NP_938969.1 | GMP synthase | Not tested | Not named | Protein | 7e-117 | 50 |
