Gene Information

Name : SEQ_1012 (SEQ_1012)
Accession : YP_002746333.1
Strain : Streptococcus equi 4047
Genome accession: NC_012471
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1000383 - 1001885 bp
Length : 1503 bp
Strand : +
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGAATAAACGTGTAAAAATTGTTGCAACACTTGGTCCTGCGGTTGAAATTCGCGGTGGTAAAAAATATGGTGAGGACGG
CTATTGGGCTGGTCAGTTGGACGTTGAACAATCAGCTAAAAAGATCGCTGAATTGATTGAAGCAGGTGCTAATGTTTTCC
GCTTTAACTTCTCACATGGTGACCACAAAGAGCAGGGTGACCGTATGGCTACTGTTCGTCTTGCTGAAAAGCTGGCACGT
CAAAAGGTTGGTTTCCTTTTGGATACAAAAGGACCAGAAATGCGTACAGAATTGTTTGCTGACGATGCCAAAGAATATAG
CTATGTGACTGGTGAGCGTATTCGTGTTGCGACAGCACAAGGCATTCAATCAACTCGTGATATGATTGCCTTGAATGTAG
CTGGTGCTCTTGATATTTATGATGAGGTTGAGGTTGGCCACACTATTCTTATTGACGATGGAAAGCTTGGCTTAAAGGTT
ATCGAGAAGGACATTGCAAAGCGTGAGTTCATCGTTGAGGTTGAAAATGATGGCATCATTGCAAAGCAAAAGGGTGTTAA
TATCCCTAATACCAAGATTCCTTTCCCAGCCTTAGCAGAACGTGATAATGCTGATATTCGTTTTGGTCTTGAGCAAGGTC
TTAACTTTATTGCTATTTCATTTGTTCGTACTGCCAAGGACGTTGAAGAGGTTCGTGAGATTTGTCGTGAAACAGGCAAT
GAGCATGTTCAATTATTTGCTAAAATCGAAAACCAACAAGGTATTGATAACCTTGATGAAATCATCGAAGCTGCAGATGG
TATCATGATTGCTCGTGGTGATATGGGGATTGAGGTGCCATTTGAAATGGTTCCAGTCTTCCAAAAAATGATTATCACCA
AGGTAAATGCAGCAGGTAAAGCAGTCATCACCGCAACTAACATGCTTGAAACAATGACTGAAAAACCACGTGCAACTCGT
TCAGAGGTATCTGACGTTTTCAACGCGGTTATTGACGGTACAGATGCGACAATGCTTTCTGGTGAATCAGCAAATGGTAA
ATACCCTGTTGAAGCAGTTCGTACAATGGCTACAATTGATAAAAATGCACAAACTCTTCTTAATGAGTATGGTCGTTTAG
ATTCATCTGCCTTCCCACGTACCAATAAAACTGACGTGATTGCTTCAGCTGTTAAAGATGCAACACACTCAATGGATATC
AAGCTTGTTGTGACCATCACTGAAACAGGAAACACAGCTCGTGCCATTTCTAAGTTCCGTCCTGATGCTGACATCTTGGC
TGTGACCTTTGATGAAAAGGTTCAACGTGCCTTGATGATTAACTGGGGTGTGATTCCAGTGCTTGCTGAAAGACCAGCAT
CAACAGATGATATGTTTGAGGTAGCAGAGCGTGTAGCTCTTGAGACTGGTTTGGTGCAATCAGGAGATAATATCGTTATT
GTTGCAGGTGTGCCAGTTGGTACAGGTGGTACAAATACAATGCGTGTTCGCACTGTAAAATAA

Protein sequence :
MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEQSAKKIAELIEAGANVFRFNFSHGDHKEQGDRMATVRLAEKLAR
QKVGFLLDTKGPEMRTELFADDAKEYSYVTGERIRVATAQGIQSTRDMIALNVAGALDIYDEVEVGHTILIDDGKLGLKV
IEKDIAKREFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIAISFVRTAKDVEEVREICRETGN
EHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMGIEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATR
SEVSDVFNAVIDGTDATMLSGESANGKYPVEAVRTMATIDKNAQTLLNEYGRLDSSAFPRTNKTDVIASAVKDATHSMDI
KLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAERPASTDDMFEVAERVALETGLVQSGDNIVI
VAGVPVGTGGTNTMRVRTVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 5e-80 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-80 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-80 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-80 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SEQ_1012 YP_002746333.1 pyruvate kinase VFG0479 Protein 8e-81 43