Gene Information

Name : leuS (SZO_01440)
Accession : YP_002743705.1
Strain : Streptococcus equi H70
Genome accession: NC_012470
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 165645 - 168146 bp
Length : 2502 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGACATTTTACAATCACAAAGCCATTGAGCCTAAGTGGCAGGCCTTTTGGGCTGATAATCATACCTTTAAAACAGGAAC
AGACGCCTCAAAGCCTAAATTTTACGCTTTAGATATGTTTCCTTATCCTTCTGGTGCAGGTCTACACGTGGGGCACCCTG
AAGGCTACACTGCGACTGATATTTTAAGCCGCTTCAAGCGTGCACAGGGCTATAATGTTCTCCACCCAATGGGCTGGGAT
GCCTTTGGTCTGCCTGCTGAGCAATACGCGATGGATACTGGGAATGACCCTGCTGAGTTTACAGCAGAAAACATTGCGAA
CTTCAAACGTCAGATCAATGCCCTTGGCTTCTCGTATGACTGGGATCGTGAGATCAATACAACTGATCCTAATTACTACA
AGTGGACACAGTGGATCTTCACAAAATTGTATGAAAAAGGCTTGGCCTATGAAGCTGAAGTGCCTGTTAACTGGGTTGAA
GAGCTGGGAACAGCTATTGCGAATGAGGAGGTTCTCCCTGATGGCACATCAGAGCGTGGAGGCTATCCAGTTGTCCGTAA
GCCCATGCGCCAATGGATGCTCAAAATCACAGCCTACGCAGAGCGCTTGCTAGCAGATCTGGAGGAAGTGGATTGGCCAG
AGTCGATCAAGGATATGCAGCGCAACTGGATTGGTAAATCAACAGGGGCTAATGTAACCTTCAAGGTCAAAGATACCGAT
AAAGACTTCACCGTCTTTACCACACGACCTGATACCCTGTTTGGTGCAACCTATGCTGTTTTGGCACCAGAACACGCCTT
AGTAGATAGCATTACTACAGCAGAGCAAGCGCAGGCTGTTGCTGAGTACAAACGCCAAGCGAGCCTCAAATCTGACCTTG
CTCGTACCGATCTTGCCAAGGAAAAAACAGGTGTCTGGACAGGAGCCTATGCGATCAACCCGGTCAATGGCAAAGAAATG
CCTATCTGGATTGCGGATTATGTGCTTGCAAGCTACGGTACAGGTGCTATCATGGCAGTGCCAGCGCATGATGAGCGTGA
CTGGGCATTTGCAAAGCAATTCAATCTTGAGATTATTCCAGTGCTTGAAGGGGGCAATGTTGATGAGGCTGCCTACACAG
AGGACGGTATTCACATTAATTCTGACTTCCTAGATGGTCTTGATAAGGCTTGTGCCATTGCTAAAATGGTGGTGTGGCTG
GAGGAGACTGGTGTCGGTCATGAAAAGGTCTCTTATCGCCTACGTGACTGGCTGTTCAGTCGTCAGCGCTACTGGGGTGA
GCCAATCCCAATCATTCATTGGGAGGACGGTACCTCGACAGCAGTTCCTGAGCAGGACCTACCACTTGTTTTGCCAGTGA
CCAAGGATATTCGCCCATCTGGTACAGGAGAATCACCACTAGCTAACTTGACTGACTGGCTTGAGGTGACCCGCGAGGAT
GGGGTCAAGGGGCGTCGTGAGACAAACACCATGCCACAGTGGGCTGGCTCAAGCTGGTATTACCTTCGCTATATTGATCC
ACATAATGATAAGCAGCTGGCTGACAAGGACCTGTTAAAGCAGTGGTTGCCAGTAGATATCTACATTGGAGGTGCAGAGC
ATGCTGTGCTTCACTTGCTTTATGCACGCTTCTGGCACAAGGTACTCTATGATCTGGGTGTAGTGCCAACCAAGGAGCCA
TTCCAAAAGCTCTTTAACCAAGGCATGATTTTAGGAACCAGCTATCGCGACCATCGTGGCGCCTTGGTCGCAACGGATAA
GGTTGACAAGCGTGACGGCAGCTTCTTTCATATGGAAACAGGCGAGGAGCTTGAGCAGGCCCCTGCTAAGATGTCTAAGT
CGCTGAAAAACGTTGTCAACCCAGATGACGTAGTGGAGCAGTACGGTGCAGATACTCTGCGTGTGTACGAAATGTTCATG
GGACCACTTGATGCCTCAATCGCTTGGTCTGAAGAAGGCCTGGAGGGAGCACGCAAGTTCCTAGATCGTGTTTACCGTTT
GATCACGACAAAGGAAATTGTTGCAGAAAATAGCGGGGCTTTAGACAAGGCTTACCATGAGACTGTTAAGGCGGTCACAG
AACAAATCGAAGGCATGAAATTCAACACTGCTATCGCCCAGCTCATGATTTTTGTCAATGCAGCCAATAAAGAGGACAAG
CTTTATGTGGCATACGCAAAAGGCTTTGTTCAGTTGCTTGCCCCATTTGCCCCACACTTGGGTGAAGAATTATGGCAGAG
CCTAACAGCTTCAGGTCAATCCATCTCGTATGTTGCATGGCCAACCCATGACGACAGCAAGCTCGTTGAAAATGATGTCG
AAATCGTTGTTCAAATTAAAGGAAAGGTTAAGGCTAAGCTTGTTGTGGCAAAAGACCTCTCAAGAGAGGAGCTAGAAAAA
GTAGCCCTAGCACATGATAAAATACAGGCTGAAATTGCAGGCAAAGAAGTGATAAAGGTTATCGCTGTTCCTAATAAGCT
CGTTAACATTGTGGTGAAATAA

Protein sequence :
MTFYNHKAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGYNVLHPMGWD
AFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREINTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLADLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
KDFTVFTTRPDTLFGATYAVLAPEHALVDSITTAEQAQAVAEYKRQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEM
PIWIADYVLASYGTGAIMAVPAHDERDWAFAKQFNLEIIPVLEGGNVDEAAYTEDGIHINSDFLDGLDKACAIAKMVVWL
EETGVGHEKVSYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPEQDLPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED
GVKGRRETNTMPQWAGSSWYYLRYIDPHNDKQLADKDLLKQWLPVDIYIGGAEHAVLHLLYARFWHKVLYDLGVVPTKEP
FQKLFNQGMILGTSYRDHRGALVATDKVDKRDGSFFHMETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM
GPLDASIAWSEEGLEGARKFLDRVYRLITTKEIVAENSGALDKAYHETVKAVTEQIEGMKFNTAIAQLMIFVNAANKEDK
LYVAYAKGFVQLLAPFAPHLGEELWQSLTASGQSISYVAWPTHDDSKLVENDVEIVVQIKGKVKAKLVVAKDLSREELEK
VALAHDKIQAEIAGKEVIKVIAVPNKLVNIVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 93