Gene Information

Name : guaA (SZO_09540)
Accession : YP_002744481.1
Strain : Streptococcus equi H70
Genome accession: NC_012470
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1064515 - 1066077 bp
Length : 1563 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACTGAAATTTCAATGTTGAATGATGTTCAAAAAATTATCGTTCTTGATTACGGTAGTCAGTACAATCAACTGATTGC
AAGACGTATTCGAGAGTTTGGTGTTTTTTCTGAACTCAAAAGCCATAACATCACTGCGCAAGAGCTTCGTGACATCAATC
CAATCGGGATTGTTCTGTCTGGTGGGCCAAATTCTGTTTACGCAGACGATGCCTTTGGTATTGATCCTGAAATCTTTGAA
TTAGGGATTCCAATTTTAGGGATTTGCTATGGCATGCAGCTAATCACACATACCTTAGGAGGCAAGGTAGTCCCAGCTGG
TCAAGCAGGTCACCGAGAATATGGTCAATCATCATTACGTTTACGCTCTGCATCAGCATTATTTGCGGGCACTCCAGATG
AGCAGCTTGTTTTGATGAGTCATGGTGATGCTGTTACAGAAATCCCAGAGGGCTTTCACCTTGTAGGAGATTCTAACGAT
TGCCCTTACGCTGCTATGGAAAATACAAAAAAGAGGCTCTACGGTATCCAATTCCACCCAGAGGTAAGACACTCTGTCTA
TGGTAATGATATTTTGAAGAACTTTGCTATCTCTATTTGTGGTGCACGTGGTGATTGGTCAATGGATAATTTCATTGACA
TGGAAATTGCTAAAATTCGCAAAACAGTCGGAGATCGTAAGGTTCTGCTAGGTTTATCTGGTGGTGTTGATTCTTCAGTT
GTTGGTGTCCTTTTACAAAAAGCTATCGGAGATCAATTAACCTGTATCTTTGTTGATCATGGGCTTCTTCGTAAAAATGA
AGGTGACCAAGTTATGGAAATGCTTGGTGGAAGATTTGGTCTCAATATTATTCGTGTTGATGCCTCAAAGCGCTTTTTAG
ATCTCCTTGCAGGTGTTGAGGATCCTGAGAAAAAACGTAAAATTATCGGTAATGAGTTTGTTTACGTTTTTGATGACGAG
GCTAGCAAGCTTGAGGGCGTTGACTTCCTTGCACAAGGAACGCTTTACACAGACATCATTGAATCTGGAACAGAAACTGC
TCAAACGATAAAATCTCACCACAATGTTGGTGGTCTGCCAGAGGATATGCAGTTTGAATTAATCGAACCCCTCAATACAC
TCTTTAAAGATGAGGTTCGTGCTCTTGGCACAGCCCTTGGTATGCCAGATGAAGTCGTCTGGCGTCAGCCTTTCCCGGGC
CCAGGCCTTGCTATTCGCATCATGGGAGAGATCACAGCAGAAAAGCTTGAAACAGTCCGCGAGTCAGATGCCATCCTTCG
AGAAGAAATTGCTAAAGCAGGACTTGATCGTGATGTGTGGCAATATTTTACAGTTAATACAGGTGTTCGTTCCGTCGGAG
TTATGGGAGATGGTCGCACCTATGACTATACCATCGCTATTCGTGCTATCACCTCAATTGACGGCATGACAGCAGACTTT
GCCCAATTGCCTTGGGAAGTCCTAAAGAAGATCTCAGTCCGAATCGTCAATGAAGTCGACCATGTTAACCGCATTGTGTA
CGACATCACCAGCAAACCACCAGCAACCGTTGAGTGGGAGTAA

Protein sequence :
MTEISMLNDVQKIIVLDYGSQYNQLIARRIREFGVFSELKSHNITAQELRDINPIGIVLSGGPNSVYADDAFGIDPEIFE
LGIPILGICYGMQLITHTLGGKVVPAGQAGHREYGQSSLRLRSASALFAGTPDEQLVLMSHGDAVTEIPEGFHLVGDSND
CPYAAMENTKKRLYGIQFHPEVRHSVYGNDILKNFAISICGARGDWSMDNFIDMEIAKIRKTVGDRKVLLGLSGGVDSSV
VGVLLQKAIGDQLTCIFVDHGLLRKNEGDQVMEMLGGRFGLNIIRVDASKRFLDLLAGVEDPEKKRKIIGNEFVYVFDDE
ASKLEGVDFLAQGTLYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTALGMPDEVVWRQPFPG
PGLAIRIMGEITAEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSIDGMTADF
AQLPWEVLKKISVRIVNEVDHVNRIVYDITSKPPATVEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-173 69
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 5e-173 69
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 5e-173 69
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-117 51