Gene Information

Name : SPT_0070 (SPT_0070)
Accession : YP_002741582.1
Strain : Streptococcus pneumoniae Taiwan19F-14
Genome accession: NC_012469
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : 2.7.7.7
Position : 51240 - 53873 bp
Length : 2634 bp
Strand : +
Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair

DNA sequence :
ATGGATAAGAAAAAATTATTATTGATTGATGGGTCTTCTGTAGCTTTTCGGGCGTTTTTTGCGCTGTATCAGCAGTTGGA
CCGTTTTAAGAATGCGGCTGGTTTGCATACCAATGCGATTTATGGTTTTCAGTTGATGTTGAGTCATTTGTTGGAGCGGG
TTGAGCCGAGTCATATTTTGGTGGCTTTTGATGCGGGAAAGACGACCTTCCGGACAGAGATGTATGCGGACTATAAGGGT
GGTCGGGCCAAGACTCCTGATGAGTTTCGTGAGCAATTTCCTTTCATTCGTGAGTTGCTGGATCATATGGGGATTCGTCA
CTATGAGCTGGCTCAGTATGAGGCGGATGACATCATTGGGACGCTGGATAAGCTAGCAGAGCAGGATGGTTTTGATATTA
CCATTGTCAGTGGGGACAAGGATTTGATTCAGCTGACGGATGAGCATACGGTGGTTGAAATTTCCAAGAAAGGTGTGGCT
GAGTTTGAGGCCTTTACGCCAGATTACCTCATGGAAGAAATGGGCCTCACACCAGCTCAGTTTATCGATCTCAAGGCGCT
CATGGGTGATAAGTCGGATAATATCCCTGGGGTGACCAAAGTCGGTGAAAAGACGGGTATTAAGCTCTTGCTGGAGCATG
GTTCGCTTGAGGGGATTTATGAAAATATTGATGGAATGAAGACTTCTAAGATGAAGGAAAATCTCATCAATGACAAGGAA
CAGGCCTTTTTATCTAAAACACTAGCGACCATTGATACCAAGGCACCGATTGCGATTGGTTTAGAGGACTTGGTCTATAG
TGGTCCAGATGTTGAAAATCTTGGGAAATTCTACGATGAGATGGGCTTCAAACAGCTAAAGCAGGCTTTAAATGTGTCGT
CAGCTGATGTGTCTGAGAGTTTGGATTTTACTATTGTTGACCAAATCAGTCAAGATATGCTGAGTGAAGAGTCTATCTTC
CACTTTGAGCTTTTTGGTGAGAATTACCATACGGATAATTTGGTTGGATTTGCCTGGTCTTGTGGGGATAAGCTCTATGC
CACAGACAAGCTTGAGCTGTTGCAAGACCCGATTTTCAAGGATTTCTTAGAAAAAACATCTCTGAGAGTTTATGACTTTA
AGAAGGTTAAAGTTCTTTTGCAACGTTTTGGTGTGGATTTGCAGGCGCCTGCTTTTGACATCCGTTTGGCTAAATACCTC
CTTTCGACTGTGGAGGACAATGAAATTGCGACCATCGCTAGTCTTTATGGTCAGACTTACTTGGTTGATGATGAAACTTT
CTACGGTAAGGGTGTTAAAAAGGCCATTCCTGAACGTGAGAAATTCTTGGAACACTTAGCTTGTAAACTTGCTGTTTTGG
TAGAAACAGAGCCTATTTTACTTGAAAAACTCAGCGAAAATGGGCAATTAGAGCTTCTTTATGATATGGAGCAACCTCTG
GCTTTTGTCCTTGCCAAGATGGAAATTGCTGGGATTATGGTCAAGAAAGAGACCTTGCTTGAGATGCAGGCTGAAAATGA
GCTTGTCATTGAAAAACTGACTCAAGAGATTTACGAGCTGGCTGGTGAGGAGTTTAATGTCAACTCGCCTAAGCAGTTGG
GCGTGCTTCTCTTTGAGAAATTGGGACTTCCTCTAGAATACACTAAGAAAACCAAGACAGGTTATTCGACAGCAGTGGAT
GTGTTGGAGCGTCTCGCTCCTATTGCTCCGATTGTTAAGAAAATCCTGGATTACCGTCAAATTGCTAAGATTCAATCTAC
TTATGTAATTGGCTTGCAGGACTGGATTTTGGCTGATGGAAAGATTCATACTCGCTATGTGCAGGATTTGACCCAGACCG
GGCGTTTGTCTAGTGTGGATCCAAACTTGCAAAATATTCCTGCCCGATTGGAACAGGGGCGCTTGATTCGGAAGGCTTTT
GTGCCAGAGTGGGAGGATAGTGTGCTACTCAGCTCTGACTATTCACAGATTGAATTGCGCGTTTTGGCGCATATTTCTAA
GGATGAGCACTTGATTAAGGCCTTCCAAGAGGGGGCAGATATCCATACTTCGACAGCCATGCGGGTCTTTGGCATTGAGC
GTCCTGATGATGTGACTGCAAACGACCGTCGCAATGCCAAGGCAGTTAACTTTGGAGTGGTTTATGGGATTTCAGACTTT
GGCTTGTCTAATAATTTGGGAATTAGTCGTAAGGAAGCCAAAGCCTACATTGATACCTACTTTGAACGTTTTCCAGGTAT
TAAAAACTACATGGATGAAGTGGTGCGGGAGGCGCGTGATAAGGGCTATGTAGAGACCCTCTTTAAGCGTCGCCGTGAGT
TGCCAGATATCAATTCGCGCAACTTCAATATTCGTGGTTTTGCGGAGCGAACTGCTATCAACTCACCTATCCAGGGTTCG
GCAGCAGATATTCTCAAGATTGCCATGATTCAGCTGGATAAAGCCTTGGTTGCAGGTGGTTATCAGACTAAGATGCTGTT
ACAAGTGCACGATGAAATCGTCCTTGAAGTGCCTAAATCTGAATTGGTAGAGATGAAAAAATTGGTGAAACAAACCATGG
AAGAAGCCATTCAACTCAGTGTTCCTCTTATCGCAGATGAGAATGAAGGGGCAACCTGGTACGAGGCTAAATAA

Protein sequence :
MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQLMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKG
GRAKTPDEFREQFPFIRELLDHMGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEGIYENIDGMKTSKMKENLINDKE
QAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNVSSADVSESLDFTIVDQISQDMLSEESIF
HFELFGENYHTDNLVGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAFDIRLAKYL
LSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKLAVLVETEPILLEKLSENGQLELLYDMEQPL
AFVLAKMEIAGIMVKKETLLEMQAENELVIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVD
VLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAF
VPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGISDF
GLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQGS
AADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEAIQLSVPLIADENEGATWYEAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 0.0 73