Gene Information

Name : leuS (SPT_0302)
Accession : YP_002741802.1
Strain : Streptococcus pneumoniae Taiwan19F-14
Genome accession: NC_012469
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 259051 - 261552 bp
Length : 2502 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGAGTTTTTATAATCATAAAGAAATTGAGCCTAAGTGGCAGGGCTACTGGGCAGAACATCATACATTTAAGACAGGAAC
AGATGCATCAAAACCTAAGTTTTATGCGCTTGATATGTTCCCTTATCCGTCTGGAGCTGGTCTGCACGTAGGACACCCAG
AAGGTTATACTGCAACCGATATCCTCAGTCGTTACAAACGTGCGCAAGGCTACAATGTCCTTCACCCAATGGGTTGGGAT
GCTTTTGGTTTGCCTGCAGAGCAATACGCTATGGATACTGGTAATGACCCAGCAGAATTTACAGCGGAAAACATTGCCAA
CTTCAAACGTCAGATCAATGCGCTTGGATTTTCTTATGACTGGGATCGTGAAGTCAACACAACAGATCCAAACTACTACA
AGTGGACTCAATGGATTTTCACCAAGCTTTACGAAAAAGGCTTGGCCTATGAAGCTGAAGTGCCAGTAAACTGGGTTGAG
GAATTGGGAACTGCCATTGCCAATGAAGAAGTGCTTCCTGACGGAACTTCTGAGCGTGGAGGCTATCCAGTTGTCCGCAA
ACCAATGCGCCAATGGATGCTCAAAATCACGGCTTACGCAGAGCGCTTGCTCAATGACTTAGATGAACTAGATTGGTCAG
AGTCTATCAAGGATATGCAACGCAACTGGATTGGTAAATCAACTGGTGCCAATGTAACTTTCAAAGTAAAAGGAACAGAC
AAGGAATTTACAGTCTTTACTACTCGTCCGGACACACTTTTCGGTGCGACTTTCACTGTCTTGGCTCCTGAACATGAATT
AGTAGACGCTATCACAAGTTCAGAGCAAGCAGAAGCTGTAGCAGACTATAAACACCAAGCCAGCCTTAAGTCTGACTTGG
TTCGTACAGACCTTGCTAAGGAAAAAACTGGTGTTTGGACTGGTGCTTATGCCATCAACCCTGTCAATGGTAAGGAAATG
CCAATCTGGATTGCGGACTATGTTCTTGCTAGTTATGGAACAGGTGCGGTTATGGCTGTGCCTGCCCACGACCAACGTGA
CTGGGAATTTGCCAAACAATTTGACCTTCCAATCGTCGAAGTACTTGAAGGTGGAAATGTCGAAGAAGCTGCCTACACAG
AGGATGGCCTGCATGTCAATTCAGACTTCCTAGATGGATTGAACAAAGAAGACGCTATTGCCAAGATTGTGGCTTACTTG
GAAGAAAAAGGCTGTGGTCAGGAGAAGGTTACCTACCGTCTCCGCGACTGGCTCTTTAGCCGTCAACGTTACTGGGGTGA
ACCAATTCCAATTATTCATTGGGAAGATGGAACTTCAACAGCTGTTCCTGAAACTGAATTGCCGCTTGTCTTGCCTGTCA
CCAAGGACATCCGTCCTTCAGGTACCGGTGAAAGTCCACTAGCTAACTTGACAGACTGGCTTGAAGTGACTCGTGAAGAT
GGTGTCAAAGGTCGTCGTGAAACTAACACCATGCCACAATGGGCTGGTTCAAGCTGGTACTACCTTCGCTATATTGACCC
GCACAATACTGAGAAATTGGCTGATGAGGACCTCCTCAAACAATGGTTGCCAGTAGATATCTACGTGGGTGGTGCGGAAC
ATGCTGTACTTCACTTGCTTTATGCTCGTTTCTGGCATAAATTCCTCTATGACCTCGGTGTTGTTCCGACTAAGGAACCA
TTCCAAAAACTCTTTAACCAAGGGATGATTTTGGGAACAAGCTACCGTGACCACCGTGGTGCTCTTGTGACAACCGACAA
GGTTGAAAAACGTGATGGTTCCTTCTTCCATGTAGAAACAGGGGAAGAGTTGGAGCAAGCGCCAGCCAAGATGTCTAAAT
CGCTCAAGAACGTTGTTAACCCAGACGATGTGGTGGAACAATACGGTGCCGATACCCTTCGTGTTTATGAAATGTTTATG
GGACCACTCGATGCTTCGATTGCTTGGTCAGAAGAAGGTTTGGAAGGAAGCCGTAAGTTCCTTGACCGAGTTTACCGTTT
GATTACAAGTAAAGAAATCCTTGCGGAAAACAATGGTGCTCTTGACAAGGCTTACAACGAAACAGTCAAAGCTGTTACTG
AGCAAATTGAGTCTCTCAAATTCAACACAGCTATTGCCCAACTTATGGTCTTTGTCAATGCTGCTAACAAGGAAGATAAG
CTTTATATTGACTATGCCAAAGGCTTTATTCAATTGATTGCACCATTTGCACCTCACTTGGCAGAAGAACTCTGGCAAAC
AGTCGCAGAAACAGGTGAGTCAATCTCTTATGTAGCTTGGCCAACTTGGGACGAAAGCAAATTGGTTGAAGATGAAATTG
AAATTGTCGTCCAAATCAAAGGAAAAGTTCGTGCCAAACTCATGGTTGCTAAAGATCTATCACGTGAAGAATTACAAGAA
ATCGCTTTAGCTGATGAAAAAGTCAAAGCAGAAATTGACGGTAAGGAAATCGTGAAAGTAATTTCGGTACCGAATAAACT
CGTTAATATCGTCGTTAAATAA

Protein sequence :
MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWD
AFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKDMQRNWIGKSTGANVTFKVKGTD
KEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQAEAVADYKHQASLKSDLVRTDLAKEKTGVWTGAYAINPVNGKEM
PIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVAYL
EEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED
GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEP
FQKLFNQGMILGTSYRDHRGALVTTDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM
GPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALDKAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDK
LYIDYAKGFIQLIAPFAPHLAEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREELQE
IALADEKVKAEIDGKEIVKVISVPNKLVNIVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 90