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Name : tkt2 (SPT_2025) Accession : YP_002743358.1 Strain : Streptococcus pneumoniae Taiwan19F-14 Genome accession: NC_012469 Putative virulence/resistance : Unknown Product : transketolase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0021 EC number : 2.2.1.1 Position : 1887464 - 1889440 bp Length : 1977 bp Strand : - Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo DNA sequence : ATGTCAAATCTATCTGTTAATGCAATTCGTTTTCTAGGTATTGACGCCATTAATAAAGCCAACTCAGGTCATCCAGGTGT GGTTATGGGAGCGGCTCCGATGGCTTACAGCCTCTTTACAAAACAACTTCATATCAATCCAGCTCAACCAAATTGGATTA ACCGCGACCGCTTTATTCTTTCAGCAGGTCATGGTTCAATGCTCCTTTATGCTCTTCTTCACCTTTCTGGTTTTGAAGAT GTCAGCATGGATGAGATTAAGAGCTTCCGTCAATGGGGTTCAAAAACACCAGGTCACCCAGAATTTGGTCATACGGCAGG GATTGATGCTACGACAGGTCCTCTAGGGCAAGGGATTTCAACTGCTACTGGTTTTGCCCAAGCAGAACGTTTCTTGGCAG CCAAATATAACCGTGAAGGCTACAATATCTTTGACCACTATACTTACGTTATCTGTGGAGACGGAGACTTGATGGAAGGT GTCTCAAGCGAGGCAGCTTCATACGCAGGTTTGCAAAAACTTGATAAGTTGGTTGTTCTTTATGATTCAAATGATATCAA CTTGGATGGTGAGACAAAGGATTCCTTTACAGAAAGTGTTCGTGACCGTTACAATGCCTACGGTTGGCATACTGCCTTGG TTGAAAATGGAACAGACTTGGAAGCCATCCATGCTGCTATCGAAACAGCAAAAGCTTCAGGCAAGCCATCTTTGATTGAA GTGAAGACGGTTATTGGATATGGTTCTCCAAACAAACAAGGAACTAATGCTGTACACGGCGCCCCTCTTGGAGCAGATGA AACTGCATCAACTCGCCAAGCCCTCGGTTGGGACTACGAACCATTTGAAATTCCAGAACAAGTATATGCTGATTTCAAAG AACATGTTGCAGACCGTGGCGCATCAGCTTATCAAGCTTGGACTAAATTAGTTGCAGATTATAAAGAAGCTCATCCAGAA CTGGCTGCAGAAGTAGAAGCCATCATCGACGGACGTGATCCAGTCGAAGTGACTCCAGCAGACTTCCCAGCTTTAGAAAA TGGTTTTTCTCAAGCAACTCGTAATTCAAGTCAAGATGCCTTGAATGTTGTGGCAGCTAAATTACCAACCTTCCTAGGTG GATCAGCTGACCTTGCTCACTCAAACATGACTTATATCAAGACGGATGGACTTCAAGACGATACCAATCGCTTGAATCGT AACATTCAGTTTGGTGTTCGTGAATTTGCAATGGGAACAATCTTGAACGGGATGGCCCTTCATGGTGGACTTCGTGTATA CGGTGGAACTTTCTTCGTCTTCTCTGACTATGTGAAGGCAGCTGTCCGCTTGTCAGCCTTACAAGGACTTCCTGTGACTT ATGTCTTTACCCATGATTCAATCGCAGTTGGGGAAGATGGTCCGACTCACGAACCAGTTGAGCATTTAGCAGGTCTTCGT GCTATGCCAAATCTAAATGTTTTCCGTCCAGCAGATGCGCGTGAAACGCAAGCAGCTTGGTACCTTGCAGTGACAAGTGA GAAAACACCAACTGCCCTTGTCTTGACACGTCAAAACTTGACTGTTGAAGATGGAACAGACTTCGACAAGGTTGCTAAAG GTGCTTATGTTGTATATGAAAATGCAGCCGACTTTGATACCATCTTGATTGCGACAGGTTCAGAGGTTAATCTTGCTGTC TCAGCTGCTAAAGAATTGGCTAGTCAAGGCGAAAAAATCCGCGTAGTCAGCATGCCATCTACAGATGTCTTTGATAAACA AGATGCAGCTTACAAGGAAGAAATTCTTCCAAATGCAGTCCGCCGTCGTGTTGCAGTCGAAATGGGTGCAAGTCAAAACT GGTACAAATATGTTGGTCTCGATGGTGCCGTTCTAGGTATTGATACCTTCGGAGCCTCTGCCCCAGCACCAAAAGTATTG GCAGAATATGGCTTTACTGTCGAAAATCTTGTAAAAGTTGTTCGAAATTTGAAATAA Protein sequence : MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLHINPAQPNWINRDRFILSAGHGSMLLYALLHLSGFED VSMDEIKSFRQWGSKTPGHPEFGHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGTDLEAIHAAIETAKASGKPSLIE VKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALGWDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPE LAAEVEAIIDGRDPVEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQDDTNRLNR NIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGLPVTYVFTHDSIAVGEDGPTHEPVEHLAGLR AMPNLNVFRPADARETQAAWYLAVTSEKTPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAV SAAKELASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAVLGIDTFGASAPAPKVL AEYGFTVENLVKVVRNLK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| tktA | AAO17218.1 | TktA | Not tested | tcd island | Protein | 1e-154 | 50 |
| APECO1_2641 | YP_859417.1 | transketolase | Not tested | Not named | Protein | 1e-147 | 48 |
