Gene Information

Name : SP70585_0092 (SP70585_0092)
Accession : YP_002739404.1
Strain : Streptococcus pneumoniae 70585
Genome accession: NC_012468
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : 2.7.7.7
Position : 69183 - 71816 bp
Length : 2634 bp
Strand : +
Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair

DNA sequence :
ATGGATAAGAAAAAATTATTATTGATTGATGGGTCTTCTGTAGCTTTTCGGGCGTTTTTTGCGCTGTATCAGCAGTTGGA
CCGTTTTAAGAATGCGGCTGGTTTGCATACCAATGCGATTTATGGTTTTCAGTTGATGTTGAGTCATTTGTTGGAGCGGG
TTGAGCCGAGTCATATTTTGGTGGCTTTTGATGCGGGAAAGACGACCTTCCGGACAGAGATGTATGCGGACTATAAGGGT
GGTCGGGCCAAGACTCCTGATGAGTTTCGTGAGCAATTTCCTTTCATTCGTGAGTTGCTGGATCATATGGGGATTCGTCA
CTATGAGCTGGCTCAGTATGAGGCGGATGACATCATTGGGACGCTGGATAAGCTAGCAGAGCAGGATGGTTTTGATATTA
CCATTGTCAGTGGGGACAAGGATTTGATTCAGCTGACGGATGAGCATACGGTGGTTGAAATTTCCAAGAAAGGTGTGGCT
GAGTTTGAGGCCTTTACGCCAGATTACCTCATGGAAGAAATGGGCCTCACACCAGCTCAGTTTATCGATCTCAAGGCGCT
CATGGGTGATAAGTCGGATAATATCCCTGGGGTGACCAAAGTCGGTGAAAAGACGGGTATTAAGCTCTTGCTGGAGCATG
GTTCGCTTGAGGGGATTTATGAAAATATTGATGGAATGAAGACTTCTAAGATGAAGGAAAATCTCATCAATGACAAGGAA
CAGGCCTTTTTGTCTAAAACACTAGCGACCATTGATACCAAGGCACCGATTGCGATTGGTTTAGAGGACTTGGTCTATAG
TGGTCCAGATGTTGAAAATCTTGGGAAATTTTACGATGAGATGGGATTCAAACAGCTCAAGCAGGCTTTAAATGTGTCGT
CAGCTGATGTGGCTGAGGGTTTGGATTTTACTATTGTTGACCAAATCAGTCAAGATATGCTGAGTGAAGAGTCTATCTTC
CACTTTGAGCTTTTTGGTGAGAATTACCATACGGATAATTTGGTTGGATTTGCCTGGTCTTGTGGGGATAAGCTCTATGC
CACAGACAAGCTTGAGCTGTTGCAAGACCCGATTTTCAAGGATTTCTTAGAAAAAACATCTCTGAGAGTTTATGACTTTA
AGAAGGTTAAAGTTCTTTTGCAGCGTTTTGGTGTGGATTTGCAGGCGCCTGCTTTTGACATCCGTTTGGCTAAATACCTC
CTTTCGACTGTGGAGGACAATGAAATTGCGACCATCGCTAGTCTTTATGGTCAGACTTACTTGGTTGATGATGAAACTTT
CTACGGTAAGGGTGTTAAAAAGGCCATTCCTGAACGTGAGAAATTCTTGGAACACTTAGCTTGTAAACTTGCTGTTTTGG
TAGAAACAGAGCCTATTTTACTTGAAAAACTCAGCGAAAATGGGCAATTAGAGCTTCTTTATGATATGGAGCAACCTCTG
GCTTTTGTCCTTGCCAAGATGGAAATTGCTGGGATTATGGTCAAGAAAGAGACCTTGCTTGAGATGCAGGCTGAAAATGA
GCTTGTCATTGAAAAACTGACTCAAGAGATTTACGAGCTGGCCGGTGAGGAGTTTAATGTCAACTCGCCTAAGCAGTTGG
GCGTGCTTCTCTTTGAGAAATTGGGACTTCCTCTAGAATACACTAAGAAAACCAAGACAGGTTATTCGACAGCAGTGGAT
GTTTTGGAGCGTCTCGCTCCTATTGCTCCGATTGTTAAGAAAATCCTGGATTACCGTCAAATTGCTAAGATTCAATCTAC
TTATGTAATTGGCTTGCAGGACTGGATTTTGGCTGATGGAAAGATTCATACTCGCTATGTGCAGGATTTGACCCAGACCG
GGCGTTTGTCTAGTGTGGATCCAAACTTGCAAAATATTCCTGCCCGATTGGAACAAGGGCGCTTGATTCGGAAGGCTTTT
GTGCCAGAGTGGGAGGATAGTGTGCTACTCAGCTCTGATTATTCACAGATTGAATTGCGCGTTTTGGCGCATATTTCTAA
GGATGAGCACTTGATTAAGGCCTTCCAAGAGGGGGCAGATATCCATACTTCGACAGCCATGCGGGTCTTTGGCATTGAGC
GTCCTGATAATGTGACTGCAAATGACCGTCGCAATGCCAAGGCAGTTAACTTTGGAGTGGTTTATGGGATTTCAGACTTT
GGCTTGTCTAATAATTTGGGAATTAGTCGTAAGGAAGCCAAAGCCTACATTGATACCTACTTTGAACGTTTTCCAGGTAT
TAAAAACTACATGGATGAAGTGGTGCGGGAGGCGCGTGATAAGGGCTATGTAGAGACCCTCTTTAAGCGTCGCCGTGAGT
TGCCAGATATCAATTCGCGCAACTTCAATATTCGTGGTTTTGCGGAGCGAACTGCTATCAACTCACCTATCCAGGGTTCG
GCAGCAGATATTCTCAAGATTGCCATGATTCAGCTGGATAAAGCCTTGGTTGCAGGTGGTTATCAGACTAAGATGCTGTT
ACAAGTGCACGATGAAATCGTCCTTGAAGTGCCTAAATCTGAATTGGTAGAGATAAAAAAATTGGTGAAACAAACCATGG
AAGAAGCCATTCAACTCAGTGTTCCTCTTATCGCAGATGAGAATGAAGGGGCAACCTGGTACGAGGCTAAATAA

Protein sequence :
MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQLMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKG
GRAKTPDEFREQFPFIRELLDHMGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEGIYENIDGMKTSKMKENLINDKE
QAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIF
HFELFGENYHTDNLVGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAFDIRLAKYL
LSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKLAVLVETEPILLEKLSENGQLELLYDMEQPL
AFVLAKMEIAGIMVKKETLLEMQAENELVIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVD
VLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAF
VPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDF
GLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQGS
AADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEIKKLVKQTMEEAIQLSVPLIADENEGATWYEAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 0.0 73