Gene Information

Name : ugd (SP70585_0425)
Accession : YP_002739725.1
Strain : Streptococcus pneumoniae 70585
Genome accession: NC_012468
Putative virulence/resistance : Virulence
Product : UDP-glucose 6-dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1004
EC number : 1.1.1.22
Position : 376664 - 377875 bp
Length : 1212 bp
Strand : +
Note : identified by match to protein family HMM PF00984; match to protein family HMM PF01210; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026

DNA sequence :
ATGAAAATAGCAGTAGCAGGGACAGGTTATGTGGGTTTATCTATTGCAATTCTATTAGCGCAATATCATAAGGTTATGGC
GGTAGATGTTATTCCTGAAAAAGTAGAGCTTATCAATCGTCGCCAATCTCCCATTAAGGATGATGATATTGAAACTTATT
TAGTGGAAAAGGAATTAGACTTAGTTGCAACATTAGATGGTAATGAAGCTTATCGAGATGCTGACTTTGTCATAATTGCT
GTCCCAACTAACTATGACAGTAAAAAAAATTATTTTGATACATCTGTTGTGGAAGCAGTTATTGAGCAGATTATTGCGGT
TAATTTGAAGGCAACAATTGTCATAAAATCCACAATTCCTGTGGGATATACAGAAAGTCTCCGAACACGTTTTGGGCAAT
TTAAGATTCTCTTTAGTCCTGAATTTTTACGGGAGTCTAAAGCACTTTATGATAATCTCTATCCTAGTCGAATCATCGTT
GGAGCAGATTTGAGAGATACGGAGCAGGTAGTTCAGGCTGAGCGGTTTGCAACTCTTTTGCAGGAAGGTTCACTTAAACC
TGATGTTGAGACCTTAATTATGGGTGTAACAGAGGCAGAAGCAGTCAAACTATTTGCCAACACCTATTTGGCTTTGCGGG
TTTCTTACTTTAACGAATTGGATACCTATGCGGAGATAAAGGGATTGGACACTAAATCCATCATTGACGGAGTAGGGTTA
GATCCACGAATTGGTAGCCATTATAACAATCCGTCATTTGGTTATGGAGGTTATTGTCTTCCCAAAGATAGTAAGCAGTT
GCTGGCGAATTATCATGATGTACCACAAAATATGATGACAGCTATTGTAGAAAGTAACCGTACTCGCAAGTATTTTATTG
CCGATCGTATTTTGAAAAATGCGTTGGAGCTTTCAGACGGTAATCAAACAATCATAGTAGGTGTTTACCGCTTAACTATG
AAGAGTGGTTCGGATAATTTCCGTCAATCATCAATCCAAGGTGTTATAAAATGTTTAAAGGCCAAAGGTGTAGAAGTAAT
TATCTATGAACCAACTTTGGAGGATCATAGCTTTTTCTTTGGTAATCAGGTGGTTAATGATTTGGAAGTTTTTAAGTCTA
GCAGTCAAGTGATTGTTGCCAATCGGATGGAAAAATCTTTATATGATGTGCTAGAAAAAGTTTATACAAGAGATATTTTT
CAGCGAGATTAA

Protein sequence :
MKIAVAGTGYVGLSIAILLAQYHKVMAVDVIPEKVELINRRQSPIKDDDIETYLVEKELDLVATLDGNEAYRDADFVIIA
VPTNYDSKKNYFDTSVVEAVIEQIIAVNLKATIVIKSTIPVGYTESLRTRFGQFKILFSPEFLRESKALYDNLYPSRIIV
GADLRDTEQVVQAERFATLLQEGSLKPDVETLIMGVTEAEAVKLFANTYLALRVSYFNELDTYAEIKGLDTKSIIDGVGL
DPRIGSHYNNPSFGYGGYCLPKDSKQLLANYHDVPQNMMTAIVESNRTRKYFIADRILKNALELSDGNQTIIVGVYRLTM
KSGSDNFRQSSIQGVIKCLKAKGVEVIIYEPTLEDHSFFFGNQVVNDLEVFKSSSQVIVANRMEKSLYDVLEKVYTRDIF
QRD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSP0068 YP_300158.1 UDP-glucose 6-dehydrogenase Not tested SCC15305cap Protein 8e-79 55

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ugd YP_002739725.1 UDP-glucose 6-dehydrogenase VFG0963 Protein 2e-99 58