Gene Information

Name : smpB (SPP_0982)
Accession : YP_002738145.1
Strain : Streptococcus pneumoniae P1031
Genome accession: NC_012467
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 899897 - 900364 bp
Length : 468 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGGCAAAGGGCGAGGGAAAGGTCGTCGCACAAAATAAAAAGGCACGCCACGACTATACAATCGTAGATACGCTAGAGGC
AGGGATGGTCCTGACTGGAACTGAAATCAAGAGTGTACGAGCTGCTCGAATTAATCTCAAGGATGGCTTTGCTCAAGTGA
AAAATGGAGAAGTTTGGCTGAGCAATGTTCATATCGCGCCTTACGAAGAGGGCAATATCTGGAACCAGGAACCAGAACGT
CGTCGTAAACTCCTGCTCCATAAAAGGCAAATTCAAAAATTGGAACAAGAGACCAAAGGGACAGGAATGACCTTAGTTCC
CCTTAAGGTCTATATAAAAGATGGCTACGCTAAGCTTCTTTTAGGACTTGCCAAAGGGAAGCATGACTATGACAAACGGG
AGTCTATCAAACGTCGTGAGCAAAATCGAGATATCGCGCGTGTGATGAAAGCTGTTAATCAGCGATAA

Protein sequence :
MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARINLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPER
RRKLLLHKRQIQKLEQETKGTGMTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 1e-34 61
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 1e-31 50