Gene Information

Name : SPP_0848 (SPP_0848)
Accession : YP_002738019.1
Strain : Streptococcus pneumoniae P1031
Genome accession: NC_012467
Putative virulence/resistance : Unknown
Product : pyrimidine-nucleoside phosphorylase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0213
EC number : 2.4.2.2
Position : 770533 - 771810 bp
Length : 1278 bp
Strand : +
Note : Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway

DNA sequence :
ATGAGAGCAGTTGATTTAATACAAAAAAAACGAGACGGTCAAGAACTGACTTCAAGTGAAATTGAATGGCTGGTAGAAGG
CTATGTGTCAGGAACTGTTCCTGATTATCAGATGTCTGCCTTTGCTATGGCTGTTTATTTTAAAGGAATGACGACTCGTG
AAATTTCTGATTTAACGATGAATATGGTTAAGACTGGGCAAGAGTTTGACCTGTCAGCCATTGATGGTGTGAAAGTTGAC
AAGCATTCTACTGGTGGTGTCGGCGATAAGGTAACCTTGATTTTAGCTCCTCTTGTTGCTAGCTTCGGTGTGCCTGTAGC
AAAAATGAGTGGTCGTGGTCTTGGCCATACAGGCGGAACAATTGATAAATTGGAGTCCATTAAGGGCTATCAAGTAGAAC
GTAGTCAAGAGGATTTTATTCGTCAGGTTCAGGATATTGGAGTATCTGTCATTGGGCAATCAGACCAGCTGGTCAAAGCA
GATAAGCTTCTCTATGCCCTTCGTGATGTGACCGCAACTGTCGACACGATTCCTTTGATTGCGAGTTCGGTGATGAGCAA
GAAAATTGCGGCAGGGGCGGATGCTATTTTGCTAGACGTGACTGTCGGTGAGGGTGCCTTCATGAAGACGGTTGATGAGG
CGCGTGAGTTGGCTCAAACTATGGTAGATCTTGGTAAGGTTGTTGGACGGAAGACAGTAGCAGTGATTACGGATATGAGC
CAGCCTTTGGGACGAGCGATTGGAAATCGTCTGGAAATCCTTGAAGCATTGGAGATTTTGCAAGGTCAAGGACGTCAGGA
TATTACCCACTTTATTTGTGAATTGGCTCAAATTATGCTTGGTTTGGCAAATGTTAACAAAACTGTTGAAGAAGTTCACC
AACATCTTGAGAATGGTCAAGCACTGGCTAAGTTTGAGGAAATGGTGCAAGCCCAAGGTGGAGACTTGGAAGACCTCTAT
CGTCCTGTAAATGTAGCTCATGTGGTGGAAATCCCTGCTCAGGAAACGGGTGTCATTTCAGCTCTTCCAGCTATGGACTT
TGGTCTTTATGCCATGAGGCTGGGTGCTGGTCGTGCAGTTAAGTCTGATGCCTTGGACTATGAAACAGGAATTGTTTTTG
AAAAGAAGATTGGAGACTCCGTTCAAAAGGGTGAAATTGTTGCAAAAGTATACACAAATGAAAAAATTCCACCTCAACTA
GTTACAGATTTCCAAAAATGTGTTAAAATAAGTGATGAAGTGAAAAAAATCCGTGAAATTGTAGAAATCATCTCCTAA

Protein sequence :
MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMAVYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVD
KHSTGGVGDKVTLILAPLVASFGVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELAQTMVDLGKVVGRKTVAVITDMS
QPLGRAIGNRLEILEALEILQGQGRQDITHFICELAQIMLGLANVNKTVEEVHQHLENGQALAKFEEMVQAQGGDLEDLY
RPVNVAHVVEIPAQETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYTNEKIPPQL
VTDFQKCVKISDEVKKIREIVEIIS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
deoA YP_005163381.1 Thymidine phosphorylase Not tested Not named Protein 1e-87 49