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Name : leuS (SPP_0306) Accession : YP_002737525.1 Strain : Streptococcus pneumoniae P1031 Genome accession: NC_012467 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 253785 - 256286 bp Length : 2502 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGAGTTTTTACAATCATAAAGAAATTGAGCCTAAGTGGCAGGGCTACTGGGCAGAACATCATACATTTAAGACAGGAAC AGATGCATCAAAACCTAAGTTTTATGCGCTTGATATGTTCCCTTATCCGTCTGGAGCTGGTCTGCACGTAGGACACCCAG AAGGTTATACTGCAACCGATATCCTCAGTCGTTACAAACGTGCGCAAGGCTACAATGTCCTTCACCCAATGGGTTGGGAT GCTTTTGGTTTGCCTGCAGAGCAATACGCTATGGATACTGGTAATGACCCAGCAGAATTTACAGCGGAAAACATTGCCAA CTTCAAACGTCAAATCAATGCGCTTGGATTTTCTTATGACTGGGATCGTGAAGTCAACACAACAGATCCAAACTACTACA AGTGGACTCAATGGATTTTCACCAAGCTTTACGAAAAAGGCTTGGCCTATGAAGCTGAAGTGCCAGTAAACTGGGTTGAG GAATTGGGAACTGCCATTGCCAATGAAGAAGTGCTTCCTGACGGAACTTCTGAACGTGGAGGCTATCCAGTTGTCCGCAA ACCAATGCGCCAATGGATGCTCAAAATCACGGCTTACGCAGAGCGCTTGCTCAATGACTTAGATGAACTAGATTGGTCAG AGTCTATCAAGGATATGCAACGCAACTGGATTGGTAAATCAACTGGTGCCAATGTAACTTTCAAAGTAAAAGGAACAGAC AAGGAATTTACAGTCTTTACTACTCGTCCGGACACACTTTTCGGTGCGACTTTCACTGTTTTGGCTCCTGAACATGAATT AGTAGATGCCATCACAAGCACAGAGCAAGCAGAAGCAGTAGCAGACTACAAACACCAAGCCAGCCTTAAGTCAGACTTGG CTCGTACCGACCTTGCCAAAGAAAAAACTGGTGTATGGACTGGTGCTTATGCCATCAATCCTGTCAATGGTAAGGAAATT CCAATCTGGATTGCGGATTACGTTCTTGCTAGCTATGGTACAGGTGCGGTAATGGCTGTGCCTGCCCACGATCAACGTGA CTGGGAATTTGCCAAACAATTTGACCTTCCAATCGTCGAAGTACTTGAAGGTGGAAATGTTGAAGAAGCTGCCTACACAG AAGATGGCCTTCACGTTAATTCAGACTTCCTAGATGGACTCAACAAAGAAGACGCTATTGCCAAGATTGTGGCTTGCTTG GAAGAAAAAGGCTGTGGACAAGAGAAGGTAACCTACCGTCTCCGCGACTGGCTCTTTAGCCGTCAACGTTACTGGGGTGA GCCAATCCCAATCATTCATTGGGAAGATGGAACTTCAACAGCTGTCCCTGAAAGTGAATTGCCACTTGTCTTGCCTGTAA CCAAGGATATCCGTCCCTCAGGTACTGGTGAAAGTCCACTAGCTAACTTGACAGACTGGCTTGAAGTGACTCGTGAAGAT GGTGTCAAAGGTCGTCGTGAAACAAATACTATGCCACAATGGGCAGGTTCAAGCTGGTACTACCTCCGCTATATTGACCC ACACAATACTGAGAAATTGGCTGACGAGGATCTGCTCAAACAATGGTTGCCAGTAGATATCTACGTGGGTGGTGCGGAAC ATGCTGTACTTCACTTGCTTTACGCTCGTTTCTGGCATAAATTCCTCTATGACCTCGGTGTTGTTCCAACTAAGGAACCA TTCCAAAAACTCTTTAACCAAGGGATGATTTTGGGAACAAGCTATCGTGACCACCGTGGGGCTCTTGTGGCGACTGACAA GGTTGAAAAACGTGATGGTTCTTTCTTCCATGTGGAAACAGGGGAAGAGTTGGAGCAAGCGCCAGCCAAGATGTCTAAAT CGCTCAAGAACGTTGTCAACCCAGACGATGTGGTGGAACAATACGGTGCCGATACCCTTCGTGTTTATGAAATGTTCATG GGCCCACTTGATGCTTCAATCGCTTGGTCAGAAGAAGGTCTGGAAGGAAGTCGTAAATTCCTTGACCGTGTTTATCGTTT GATTACAAGTAAGGAAATTATTGCGGAAAACAATGGTGCTCTTGACAAGGTTTATAACGAAACCGTTAAAGCTGTCACAG AGCAAATCGAATCATTGAAATTCAACACAGCTATTGCCCAACTTATGGTCTTTGTCAACGCCGCTAACAAGGAAGACAAG CTCTATGTGGACTATGCCAAAGGATTTATCCAATTGATTGCGCCATTTGCACCTCACTTGGCAGAAGAACTTTGGCAAAC TGTTGCAGCAACAGGTGAATCAATCTCTTACGTAGCTTGGCCAACATGGGATGAAAGTAAATTGGTTGAAGACGAAATCG AAATCGTCGTCCAAATCAAAGGTAAAGTCCGTGCCAAACTCATGGTTGCTAAAGACCTGTCACGTGAAGAATTGCAAGAA ATTGCTCTTGCTGATGAAAAAGTCAAGGTAGAAATTGACGGTAAGGAAATCGTGAAAGTGATTAGTGTACCAAATAAATT GGTTAATATTGTTGTAAAATAA Protein sequence : MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWD AFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKDMQRNWIGKSTGANVTFKVKGTD KEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQAEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEI PIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVACL EEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEP FQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM GPLDASIAWSEEGLEGSRKFLDRVYRLITSKEIIAENNGALDKVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDK LYVDYAKGFIQLIAPFAPHLAEELWQTVAATGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREELQE IALADEKVKVEIDGKEIVKVISVPNKLVNIVVK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 0.0 | 91 |
