Gene Information

Name : SPP_0210 (SPP_0210)
Accession : YP_002737435.1
Strain : Streptococcus pneumoniae P1031
Genome accession: NC_012467
Putative virulence/resistance : Virulence
Product : UDP-glucose 6-dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1004
EC number : 1.1.1.22
Position : 174414 - 175586 bp
Length : 1173 bp
Strand : +
Note : identified by match to protein family HMM PF00984; match to protein family HMM PF03721; match to protein family HMM TIGR03026

DNA sequence :
ATGAATATAGCAGTAATTGGTTTGGGGCATGTTGGGCTGGCCTACGCGTTACTATTTGCATCTAAATATAAAGTTGTTGC
ATATGATATAGATTCTGTAAAAATAAATAATTTAAAAAAGGGCACTCTTCCATCTAAAAATGAAGAGCTTATGAAGTTTT
TTTGCGAGAATAACTTAAATATTACTTTTTTTGATACATTTTCTGAAATTAAAAATAATATTGATTATTATATTATTGCG
CTTCCGACAGATTATGATGAGAAAATTGGTAGTTTTAATACATATGAAATCGAACAAACGGTATCGAAGATTCTGAGGGT
AAAACCTAATGGAAAGATTATTTTAAAGTCAACAGTTCCGATCGGCTTTTCAAACAAATTAAAAAGGCTGTTTGATACAA
AAAATATCATTTTTGTCCCTGAATTTTTGAGAGAAGGTTGTTCTATATATGATAATTTATATCCAAGTCGCATAGTTGTT
GGAGATGAGACAGTTGAAGGAAGAAAAATTGCAGAGTTGTTCCTTTCGATTAGTACTCATAGTACTGCCAATATTAAAAA
TGTTATGTTAGTTTCTCCTACTGAAGCAGAAGCAATTAAGCTTTTTTCTAACACATTCTTAGCTCTCCGTGTTGCTTTTT
TTAATGAACTAGATTCTTTTGCTGAGAGGAGAAGTTTAAATGCTGAAGTTGTAATAAAAGGTGTTTGTTTAGATCCAAGA
ATTGGAAATTTTTATAATAATCCTTCTTTTGGATTTGGAGGATATTGTCTTCCCAAAGATACTAAACAATTAAAAAAAGA
ATTTATAGAAATAAATGCCCCAGTGATAGAAGCGATTGATATTTCAAACACAAATAGAAAACAGTTCATAGTTAAACAAA
TATTGGAACGAAAGCCAAAGATAGTAGGAATATATAAATTGGGGATGAAATATAATTCAGATAATTACAAAGAGTCAGCT
ATTTTAAGTATAATTAATGAACTATTGATTGTCGGTATAAAAATTTTAGTATATGAACCAAATTTAAACGTTAGTATAGA
TAACGTAATTTTTGAAAAGAATTTTGAACTATTTATAAAACAAAGTGATCTAATTGTTGCAAATAGATGGGATAGGGACC
TTGAAGCTTATAAAGATAAAGTTTACACAAGGGGGATCTGGATAAGAGATTAA

Protein sequence :
MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGTLPSKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIA
LPTDYDEKIGSFNTYEIEQTVSKILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELDSFAERRSLNAEVVIKGVCLDPR
IGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVIEAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESA
ILSIINELLIVGIKILVYEPNLNVSIDNVIFEKNFELFIKQSDLIVANRWDRDLEAYKDKVYTRGIWIRD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSP0068 YP_300158.1 UDP-glucose 6-dehydrogenase Not tested SCC15305cap Protein 4e-72 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SPP_0210 YP_002737435.1 UDP-glucose 6-dehydrogenase VFG0963 Protein 1e-70 45