Gene Information

Name : SPP_0170 (SPP_0170)
Accession : YP_002737401.1
Strain : Streptococcus pneumoniae P1031
Genome accession: NC_012467
Putative virulence/resistance : Resistance
Product : macrolide export ATP-binding/permease protein MacB
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1136
EC number : 3.6.3.-
Position : 141723 - 142364 bp
Length : 642 bp
Strand : +
Note : identified by match to protein family HMM PF00005

DNA sequence : 
ATGATTGAGTTGGAAAATATTACCAAAACCATTGGGGGAAAAGTGATTTTGGATCACTTGTCTCTCAGGATTGATCAGGG
GGATTTGGTAGCTATTGTTGGAAAAAGTGGTAGTGGGAAGTCGACCTTGTTAAATTTATTAGGTTTGATAGATGGTGATT
ATAGTGGACGGTATGAGATTTTTGGTCAGACAAATCTAGCGGTCAATTCTGCTAAGTCGCAAACAATAATCCGTGAACAT
ATCTCTTATCTGTTTCAAAATTTTGCCCTGATTGATGATGAAACGGTCGAGTACAATCTCATGCTGGCGCTGAAATATGT
GAAATTGTCTAAGAAAGACAAGCTCAAAAAGGTGGAAGAGATTTTAGAGAGAGTAGGTTTGTCATCTACTTTGCATCAAA
AGGTTTCCGAGTTGTCTGGTGGCGAACAACAACGAATTGCAGTTGCTAGAGCCATCTTAAAACCCAGCCAGCTGATTTTA
GCCGATGAACCAACAGGTTCGCTAGATCCTGAAAATAGAGATTTGGTCTTGAAGTTTCTCTTAGAGATGAATCGCGAGGG
GAAAACAGTCATTATTGTGACCCACGATGCTTATGTAGCCCAACAATGTCATCGGATCATTGAATTGGGCGAGGGGAAAT
GA

Protein sequence : 
MIELENITKTIGGKVILDHLSLRIDQGDLVAIVGKSGSGKSTLLNLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREH
ISYLFQNFALIDDETVEYNLMLALKYVKLSKKDKLKKVEEILERVGLSSTLHQKVSELSGGEQQRIAVARAILKPSQLIL
ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRIIELGEGK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
Spaf_1862 YP_006310627.1 amino acid ABC transporter ATP-binding protein Not tested FWisland_2 Protein 2e-51 61

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SPP_0170 YP_002737401.1 macrolide export ATP-binding/permease protein MacB NC_012469.1.7686946. Protein 2e-85 98
SPP_0170 YP_002737401.1 macrolide export ATP-binding/permease protein MacB CP003583.1.gene613.p Protein 1e-30 45