Gene Information

Name : serS (SPJ_0398)
Accession : YP_002735498.1
Strain : Streptococcus pneumoniae JJA
Genome accession: NC_012466
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 384516 - 385790 bp
Length : 1275 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGATATCAAACGTATTCGTACAGATTTTGAAGCTGTCGCAGAAAAATTAGCTACACGTGGTGTAGATGCTGCTGT
CTTGAATGAAATGAAAGAAATCGATGCTAAACGTCGTAACATCTTGGTCAAGGTTGAAACTCTCAAAGCAGAACGTAACA
CAGTTTCTGCTGAGATTGCCCAAGCTAAGCGCAACAAGGAAAATACAGATGACAAGATTGCTGCCATGCAAAATCTATCT
GCTGAGGTTAAAGCCTTGGATGCTGAATTGGCAGAAATCGATGCTAAATTGACAGAATTTACAACGACTCTTCCAAATAT
CCCAGCTGACAGCGTTCCTGTTGGGACTGACGAAGACGACAATGTGGAAGTTCGCCGTTGGGGTACTCCACGCGAGTTTG
ACTTCGAACCTAAAGCTCACTGGGATCTCGGTGAAGACCTTGGTATCCTTGACTGGGAACGCGGTGGTAAGGTAACAGGC
GCTCGCTTCCTCTTCTATAAAGGCCTCGGTGCTCGTTTGGAACGTGCTATCTACAACTTTATGTTGGATGAACATGGAAA
AGAAGGCTATACTGAAGTCATCACACCTTACATAGTCAACCATGATTCTATGTTTGGTACTGGTCAGTATCCAAAATTTA
AGGAAGATACTTTTGAACTCAGCGATACCAACTTTGTCTTGATTCCAACTGCTGAAGTTCCTCTGACAAACTACTACCGT
GATGAAATCTTAGACGGCAAAGATCTTCCAATCTACTTCACTGCCATGAGTCCGTCATTCCGTTCTGAGGCTGGTTCTGC
CGGTCGTGATACGCGTGGCTTGATCCGTTTGCACCAATTCCACAAGGTTGAAATGGTCAAATTTGCCAAACCAGAAGAAT
CTTACGAAGAATTGGAAAAAATGACAGCCAACGCTGAAAACATTCTTCAAAAACTCAACCTTCCATACCGTGTCGTTGCT
CTCTCTACTGGAGATATGGGCTTCTCAACTGCGAAGACTTACGACTTGGAAGTGTGGATTCCAGCACAAAACAATTACCG
TGAAATCTCAAGCTGTTCAAACACAGAAGATTTCCAAGCCCGTCGTGCCCAAATCCGTTACCGTGATGAAGCAGATGGCA
AGGTGAAACTCCTTCATACCTTGAACGGTTCTGGACTTGCAGTTGGACGTACAGTGGCTGCAATTCTTGAAAATTACCAA
AATGAAGATGGTTCTGTGACCATCCCAGAAGCACTTCGTCCATACATGGGTGGAGCTGAAGTCATCAAACCATAA

Protein sequence :
MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVKVETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLS
AEVKALDAELAEIDAKLTEFTTTLPNIPADSVPVGTDEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTFELSDTNFVLIPTAEVPLTNYYR
DEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIRLHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVA
LSTGDMGFSTAKTYDLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTVAAILENYQ
NEDGSVTIPEALRPYMGGAEVIKP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 0.0 97