Gene Information

Name : SPJ_0134 (SPJ_0134)
Accession : YP_002735248.1
Strain : Streptococcus pneumoniae JJA
Genome accession: NC_012466
Putative virulence/resistance : Resistance
Product : macrolide export ATP-binding/permease protein MacB
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1136
EC number : 3.6.3.-
Position : 119303 - 119944 bp
Length : 642 bp
Strand : +
Note : identified by match to protein family HMM PF00005

DNA sequence : 
ATGATTGAGTTGGAAAATATTACCAAAACCATTGGGGGGAAAGTGATTTTGGATCGCTTGTCTCTCAGGATTGATCAGGG
GGATTTGGTTGCCATTGTTGGTAAGAGTGGTAGTGGGAAGTCGACCTTGTTAAATTTATTGGGTTTGATAGATGGTGATT
ATAGCGGACGGTATGAGATTTTTGGTCAGACAAATCTAGCGGTCAATTCTGCTAAGTCGCAAACAATAATCCGTGAACAT
ATCTCTTATCTGTTTCAAAATTTTGCCCTGATTGATGATGAAACGGTCGAGTACAATCTTATGCTGGCGCTGAAATATGT
AAAATTGTCTAAGAAAGATAAGCTCAAAAAGGTGGAAGAGATTTTAGAGAGAGTAGGTTTGTCAGCTACTTTGCATCAAA
AGGTCTCCGAGTTGTCTGGTGGCGAACAACAACGAATTGCAGTTGCTAGAGCCATCTTAAAACCCAGCCAGCTGATTTTA
GCCGATGAACCTACAGGTTCGCTGGATCCTGAAAATAGAGATTTGGTCTTGAAGTTTCTCTTAGAGATGAATCGAGAAGG
GAAAACAGTCATTATTGTGACCCACGATGCTTATGTAGCCCAACAATGTCATCGGATTATTGAATTGGGCGAGGGAAAAT
GA

Protein sequence : 
MIELENITKTIGGKVILDRLSLRIDQGDLVAIVGKSGSGKSTLLNLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREH
ISYLFQNFALIDDETVEYNLMLALKYVKLSKKDKLKKVEEILERVGLSATLHQKVSELSGGEQQRIAVARAILKPSQLIL
ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRIIELGEGK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
Spaf_1862 YP_006310627.1 amino acid ABC transporter ATP-binding protein Not tested FWisland_2 Protein 5e-51 61

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SPJ_0134 YP_002735248.1 macrolide export ATP-binding/permease protein MacB NC_012469.1.7686946. Protein 2e-85 98
SPJ_0134 YP_002735248.1 macrolide export ATP-binding/permease protein MacB CP003583.1.gene613.p Protein 2e-30 45