Gene Information

Name : PERMA_0680 (PERMA_0680)
Accession : YP_002730468.1
Strain : Persephonella marina EX-H1
Genome accession: NC_012440
Putative virulence/resistance : Resistance
Product : macrolide export ATP-binding/permease protein MacB
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1136
EC number : 3.6.3.-
Position : 637642 - 638313 bp
Length : 672 bp
Strand : -
Note : identified by match to protein family HMM PF00005

DNA sequence : 
ATGAGCATACTTATAAAACTTGAAAATATAGTTAAAGAGTACGAAAGCTTTGGAATAAGAACAAAGGTTTTAAAAGGTAT
TGATCTGACAGTCAGAAAAGGTGAGTTTGTCTCAATTATGGGTGTTTCAGGATCAGGAAAAACAACACTGATGAATATTA
TAGGTTGTCTTGATACACCAACCTCCGGAAAGTACTACTTTGAGGGAATGGATGTTTCAGATCTTGATGATGATAAACTT
TCAGAGATAAGAAATGAGTATATAGGTTTCGTATTCCAGCAGTTTTATCTTATAAACTATCTTACAGTTCTGGAAAATGT
AATTGTCCCAACAATATACTCCAGAAAACCACCTGAAAACCCGAAGGATAAAGCTAAAAAACTTCTTGAAAGGGTTGGAC
TTGAGGAGAAGCTCTCATTCAAACCAAACCAGCTTTCAGGGGGCCAGCAGCAGAGGGTAGCTATAGCAAGAGCTCTTATA
AATGATCCGGATTTAATACTTGCTGATGAACCAACAGGAGCCCTTGACAGTAAAACAGCCTCAGAGATTATGGATATATT
CAAAGAACTTAACAGAGAGGGAAAAACTATCATAGTTGTAACACACGATCCAAAAGTTGCAGGTATTGCAGATAGAATTA
TAAGGATTGAAGATGGTAAAATAATTGACTAA

Protein sequence : 
MSILIKLENIVKEYESFGIRTKVLKGIDLTVRKGEFVSIMGVSGSGKTTLMNIIGCLDTPTSGKYYFEGMDVSDLDDDKL
SEIRNEYIGFVFQQFYLINYLTVLENVIVPTIYSRKPPENPKDKAKKLLERVGLEEKLSFKPNQLSGGQQQRVAIARALI
NDPDLILADEPTGALDSKTASEIMDIFKELNREGKTIIVVTHDPKVAGIADRIIRIEDGKIID

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
Spaf_1862 YP_006310627.1 amino acid ABC transporter ATP-binding protein Not tested FWisland_2 Protein 5e-34 44
Cp1002_1464 YP_005681730.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 7e-33 42
CpC231_1466 YP_005683828.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 6e-34 41
cpfrc_01473 YP_003783873.1 hypothetical protein Not tested PiCp 5 Protein 6e-34 41
CpI19_1473 YP_005685914.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 6e-34 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
PERMA_0680 YP_002730468.1 macrolide export ATP-binding/permease protein MacB NC_012469.1.7686878. Protein 8e-54 55
PERMA_0680 YP_002730468.1 macrolide export ATP-binding/permease protein MacB CP001581.1.gene798.p Protein 1e-39 48
PERMA_0680 YP_002730468.1 macrolide export ATP-binding/permease protein MacB CP001581.1.gene598.p Protein 2e-39 47
PERMA_0680 YP_002730468.1 macrolide export ATP-binding/permease protein MacB NC_008702.1.4606598. Protein 2e-38 43
PERMA_0680 YP_002730468.1 macrolide export ATP-binding/permease protein MacB NC_012469.1.7686946. Protein 3e-29 41