Gene Information

Name : hemC (PERMA_0444)
Accession : YP_002730234.1
Strain : Persephonella marina EX-H1
Genome accession: NC_012440
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 398301 - 399227 bp
Length : 927 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
TTGAGGATAAGAATAGGAACAAGAAAAAGTAAACTTGCCCTCTGGCAGGCAAATTATATTGCAGATCAGCTGAAGAAACA
TTTTCCTGATCTGGAAGTTGAACTTGTAAAGATAGTTACTAAAGGTGACAAGATCCTTGATGTCCCACTTGCTAAGGTGG
GAGGGAAAGGTCTTTTTGTTAAAGAGATAGAGGAAGCTATGCTCAGAAATGAGATAGATATAGCTGTTCATTCTTTAAAG
GATGTTCCAACATACTTTCCTGAAGGTCTTGGGCTTGTTGCTATCACCGAGAGGGAAGATCCAAGGGATGCTTTCCTGTC
TGTTAAATACAACTCCATTGAGGATATGCCTGAAGGGGCTGTTCTTGGTACGAGCTCTCTTAGAAGAAAAGCCCAGATAA
TGATGAAAAGAAAAGATATCCGTATAGAAGACCTTAGAGGGAATGTTGATACGAGAATAAGAAAGCTTGAAGAAGGCCAG
TATGACGGGATTATCCTCGCCTATGCAGGTCTTAAAAGACTTGGACTTGAGGGTAAGGTCAGACAGATACTCCAGCCTGA
TTATATGATACCTGCTGTTGCACAGGGATTTCTTGGAATTGAGGCAAGGCTTGATGATGAAAAAACAAGGGAGATAGTAT
CGGTTCTTAATCATAGAGAAAGTGAGATAAGGGCAAAAGCTGAGAGGGCATTCTTAAAAACACTTGAAGGTGGCTGTCAG
GTTCCACTTGCAGGATACTCTGAGATAGTAAATGGAAAGCTGAAGATAACTGGGTTTGTTTCTGATCTTACAGGAGATAG
AGTTTTCAGGGATAGTATGGAAGGAAGTCTTGAAGATGCTGAGAGTTTAGGTGTTAAGCTTGCAGAAAAACTGCTTTCAG
ATGGAGCAAAGGAAGTTCTTGAAGAAATATACTCCGGATCAGAATAA

Protein sequence :
MRIRIGTRKSKLALWQANYIADQLKKHFPDLEVELVKIVTKGDKILDVPLAKVGGKGLFVKEIEEAMLRNEIDIAVHSLK
DVPTYFPEGLGLVAITEREDPRDAFLSVKYNSIEDMPEGAVLGTSSLRRKAQIMMKRKDIRIEDLRGNVDTRIRKLEEGQ
YDGIILAYAGLKRLGLEGKVRQILQPDYMIPAVAQGFLGIEARLDDEKTREIVSVLNHRESEIRAKAERAFLKTLEGGCQ
VPLAGYSEIVNGKLKITGFVSDLTGDRVFRDSMEGSLEDAESLGVKLAEKLLSDGAKEVLEEIYSGSE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 7e-77 54
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 7e-77 54