Gene Information

Name : guaA (PERMA_0029)
Accession : YP_002729827.1
Strain : Persephonella marina EX-H1
Genome accession: NC_012440
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 29016 - 30554 bp
Length : 1539 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
TTGGAACATAGAGGAATTATAATCTTAGATTTTGGTTCACAGTACACACAGCTTATAGCAAGAAGGATAAGGGAGTTACA
TATATTCAGTGAGATACTCCCTTTTAATGCATCTGTAGAAGAGATAATGAGTCATAATCCTAAAGGAATTATATTCTCAG
GTGGTCCTGCATCTGTTTACCATCCTGACGCACCAAAACCTGATGAGAGGGTTTTTGATCTTGGACTTCCCATACTGGGA
ATATGCTACGGTCTACAGCTCATAACTCACCATTTTGGCGGTGAGGTTGTTAAGGCTGAGAGACACGAGTACGGAAGGGC
TGAGCTTGAGATACTGGATCATTCTGATCTTTTCAAGGATATACCAAATGAGATACATGTCTGGATGTCTCACGGTGATA
GGGTTACAAAGCTCCCTGAAGGTTTTGAGCCTATAGCAAGAACCTATAACGCACCTTTTGCAGCTATAAGAAACAGAGAA
AAGAAGATATGGGGTGTACAGTTCCATCCGGAGGTTGCACATACATACCTTGGTAAGGATATACTTAAAAATTTTGCTGT
TCAGATCTGTGGTTGCAGTCAGGACTGGACGATGGGAAGCTTCCTTATGGAAAAGGAAGTTGAGATAAGAAAGATGGTTG
GAGATAAAAAGGCTATATGTGCCCTTTCGGGAGGAGTGGACTCATCAGTCGCTGCAGTTCTTGTTCACAACGCAATAGGG
GATAATCTCACATGTATCTTTGTTGATAACGGACTTTTAAGAAAAGGTGAGAGGGAAAAGGTAGAGAAAACATTCAGGGA
TCATTTCCATATTCCTCTTATCGTTGTTGATGCGAGGGAGAGATTTTTAGAGGCTTTAAAAGGTGTTACAGATCCTGAAC
AGAAAAGAAAGATAATAGGAAATCTTTTTATTGAGATATTTGAGGAAGAGGCAAAAAAGATACCTGATGTTGAGTTCCTC
GTTCAGGGGACACTTTACCCTGATGTTATTGAGAGTGTTTCTGTAAAAGGTCCATCAGCAGTTATAAAGACACACCATAA
TGTAGGTGGACTTCCTGAAAAGATGAATCTGAAGCTTATTGAGCCTTTAAGAGAGCTTTTCAAGGATGAGGTTAGAGAGC
TTGGTAAAGAGCTCGGTCTTCCAGATGAGATCATTTACAGACAGCCTTTCCCCGGACCTGGTCTTGCTATAAGGATAATA
GGTGAGGTAAATAAGGAAGATCTTGAGATACTCAGGGAGGCTGATGCTATAGTTGTTGAGGAGGTTAAAAAGGCTGGTCT
TTACAGACAGCTCTGGCAGTCATTTGCCGTTCTTCTCCCTGTTCTTACTGTTGGGGTTATGGGAGATTACAGAACGTATG
AAAAGGTTATAGCTGTGAGAGCAGTCGAATCAACAGATGGTATGACAGCAGACTGGGCGAGACTTCCTTACGATCTCCTT
GACAGAATTATGAGAAGAATTATAAATGAAGTAAAGGGTGTTAACAGGGTTGTTTATGATATTACATCAAAGCCACCTGG
AACTATAGAGTGGGAGTGA

Protein sequence :
MEHRGIIILDFGSQYTQLIARRIRELHIFSEILPFNASVEEIMSHNPKGIIFSGGPASVYHPDAPKPDERVFDLGLPILG
ICYGLQLITHHFGGEVVKAERHEYGRAELEILDHSDLFKDIPNEIHVWMSHGDRVTKLPEGFEPIARTYNAPFAAIRNRE
KKIWGVQFHPEVAHTYLGKDILKNFAVQICGCSQDWTMGSFLMEKEVEIRKMVGDKKAICALSGGVDSSVAAVLVHNAIG
DNLTCIFVDNGLLRKGEREKVEKTFRDHFHIPLIVVDARERFLEALKGVTDPEQKRKIIGNLFIEIFEEEAKKIPDVEFL
VQGTLYPDVIESVSVKGPSAVIKTHHNVGGLPEKMNLKLIEPLRELFKDEVRELGKELGLPDEIIYRQPFPGPGLAIRII
GEVNKEDLEILREADAIVVEEVKKAGLYRQLWQSFAVLLPVLTVGVMGDYRTYEKVIAVRAVESTDGMTADWARLPYDLL
DRIMRRIINEVKGVNRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 7e-141 56
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-141 56
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-141 56
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-128 54