Gene Information

Name : pyk (PERMA_0022)
Accession : YP_002729821.1
Strain : Persephonella marina EX-H1
Genome accession: NC_012440
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 23485 - 24924 bp
Length : 1440 bp
Strand : -
Note : identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064

DNA sequence :
ATGAGAAGGACAAAAATAGTTGCCACACTCGGTCCTGCAACAAGCTCCGAAGAGATGATAGAGAAGCTTATCCTCTCTGG
AGTTGATGTTTTCAGATTCAACTTCTCACATGGGGATCACGAAACACATCTACAGAATCTGAAAAAAGTAAGGAGCATAT
CCGAAAAACTTGGAAAACCTATCGCTGTTCTTCAGGATCTTTCAGGACCAAAGATAAGAATTGGTGTTGTTGAGGAACCT
TTTTACCTCCATTTTGAAGACAGGATAAGGATAGTAAAAGAAGAGGTTATAGGAAACAAAGAAAGAATAAGCATAAACTA
TCCTGAGGTTTTAGATCAGCTTGAGAAGGGTAGTTATATATACATATCTGATGGATCAATAAGGCTTCAGGTTGTTGACA
AAGACGATGAGGGAATAACAGCAAAGGTTATCGTAGGTGGGATGGTTTCTTCAAAGAAAGGGGTTAACTTCCCAAATGTA
AGGCTTAACATACCATCAATAACTGAAAAGGACAAAAAGGATATCAAGTTTGCCATAGAGGAAGATATTGATCTTATAGC
TCTATCTTTTGTTAAAACAGCTGAAGATGTGATACAGGCAAAGGAGATAATAAGATCCTACGGAGGAGATACACCTTTAT
TTGCAAAGATAGAGAAGCATGAAGCTATTGAGAATATAGACCGGATAATAGAAGAGGCAGACGGAATAATGGTGGCAAGG
GGAGACCTCGGTGTTGAGATAGATATGGAAAAGGTTCCTGTTCTCCAGAAGATGATAATAAAGAAAGCTAACGAGAAGGG
AAAACCTGTCATAACGGCGACACAGATGCTGACATCAATGGTATCATCTCCAAGGCCTACAAGGGCTGAGGTTTCAGATA
TAGCAAATGCTGTTCTTGATGGAACAGATGCTGTTATGCTCTCAGATGAAACAACAGTAGGGAAGTATCCTTTAGAGGCT
GTTAAAGTTATGGAGAGAACAATCTGTGAAACGGAAAAAGTGTATCCATTCTTTACAGAAAAAGAGCATGCACCTACAGA
CCCTTCTCTTTCTGTAGCTTACGCAAGTAACTCTCTTGCAAAAAATCTGAACGGAAAAGCCATAGCCGTTTTCACAAAAA
CAGGCAGAACTGTAAGAAATGTAGCGAAGTTCAGACCTAAATGTCCTGTTCTTGCTCTAACACATGACGAAAAAACCCTC
AGAAGACTCAATATTGTCTGGGGAGTAAAACCCTATATGATAATTAAGGAGGAAAAAGATACAGACAGGATGCTGTGTGA
GTTCATAGGAAAGGCATACACAGAGGATTACAGAACTGATGAGATAGTTATAACGCTAATAGGATATGTTGGAAGCATAC
CAGGTTCAACAAATATAATAAGGATACTTATGGAAGGTGACGTGAAACAGCTGCTTAAAGAGTGCAGAATCAGTCAATAA

Protein sequence :
MRRTKIVATLGPATSSEEMIEKLILSGVDVFRFNFSHGDHETHLQNLKKVRSISEKLGKPIAVLQDLSGPKIRIGVVEEP
FYLHFEDRIRIVKEEVIGNKERISINYPEVLDQLEKGSYIYISDGSIRLQVVDKDDEGITAKVIVGGMVSSKKGVNFPNV
RLNIPSITEKDKKDIKFAIEEDIDLIALSFVKTAEDVIQAKEIIRSYGGDTPLFAKIEKHEAIENIDRIIEEADGIMVAR
GDLGVEIDMEKVPVLQKMIIKKANEKGKPVITATQMLTSMVSSPRPTRAEVSDIANAVLDGTDAVMLSDETTVGKYPLEA
VKVMERTICETEKVYPFFTEKEHAPTDPSLSVAYASNSLAKNLNGKAIAVFTKTGRTVRNVAKFRPKCPVLALTHDEKTL
RRLNIVWGVKPYMIIKEEKDTDRMLCEFIGKAYTEDYRTDEIVITLIGYVGSIPGSTNIIRILMEGDVKQLLKECRISQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 4e-68 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 6e-68 42
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 4e-68 42
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 4e-68 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_002729821.1 pyruvate kinase VFG0479 Protein 2e-68 42