Gene Information

Name : PERMA_1739 (PERMA_1739)
Accession : YP_002731503.1
Strain : Persephonella marina EX-H1
Genome accession: NC_012440
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence ClpC/mecB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1682780 - 1685230 bp
Length : 2451 bp
Strand : +
Note : identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728

DNA sequence :
ATGTTTGAAAAATTTACGGAAAGAGCAAGAAAAGTAATACTGAATGCGAGAGAGAAGGCATTAGAATATAGAAGCAATTA
CCTGGGCAGTGAACATCTGCTCCTTTCTCTACTTGAGGAAGAGGACATTCCTGTTCTTGTTCTTTCAAGATTTGGTCTTA
CTGTTGACAAGGTAAAAAGAACCCTTACATCACAGATGGTTCACGGATCACACTCAGGTGAGGTTCTTTTTGCTCCTGAT
GCGAAGAGAGTTCTTGAGTTTGCCGTTGAAGAGGCCAGAATACTTCACCACCAGTTTGTAGGGCCTGAACATCTCCTTAT
CGGGATAGTCCGTGAGAAGACAGGTCTTGGCGGTAGAGTTTTAAGAGGTTTTGGTATAGATGAGTACTCAATAAGAAGGG
AGATACTCCAGATACTTGGAGAGATACCACCTCAGGAGCAGGTGAAACAGGTTCCTACACCTAATATAGACAGATTCAGC
AGAGATCTTACAGCTCTTGCAAGGGAAGGAAAGCTTGATCCTGTTATAGGAAGGGATAAGGAGATAGACAGGGTTATACA
GATACTCTCAAGAAGAAGAAAGAACAACCCTGTTCTTATAGGTGAGCCAGGTGTAGGTAAAACATCAATTGTTGAAGGTC
TCGCCCAGAGAATAGCAAATAAGGAAGTACCTGAGACATTACAGTCTAAAAGAATTGTTGCTCTTGATCTTGCTGCCCTT
GTTGCAGGAACAAAGTACAGAGGACAGTTTGAAGAAAGGCTTAAGAATATACTTAAAGAGCTTGAAAAAGCACCTTACAT
AATACTTTTCATAGATGAGCTTCATACACTTGTAGGAGCAGGAGCAGCTGAAGGTTCAATAGATGCATCAAATATGTTAA
AACCGGCTCTTGCAAGGGGAGAGATACAGGTTATAGGAGCAACAACAATAGATGAGTACAGAAAGTACATAGAGAAGGAT
GGAGCACTTGAGAGAAGATTCCAGCCAGTTCTTGTAGAGCCTCCTACACCTGAAGATACTGTAAAGATACTTATGGGTCT
GAAGAAGAAGTTTGAGGAGTTCCACGAGGTTGAGTACACAAAGGATGCTGTTGAAAAGGCTGTTGAGTACTCAGTTAAGT
ATATAACAGAAAGACAGCTGCCAGATAAGGCTATAGATCTGATAGATGAGGCTGGAGCATGGGTGAGAATAAGGGAGATG
GAACTTCCTCCTAAGCTCAAAAAGATAGAGGACAAGATAAGAAAGATAGAGGAAGAAAAGGCTAAAGCTGCAAAAGAGCA
GGATTATGAAAAAGCTGCAAAACTGAGAGATGAAGAGCTGAAACTGAGGGCTAAGTTTGAGACATTAAAGGCTGAATGGA
AGGAGAAAAGGAAGGTTAAAAAACCTAAGGTTAAAGATCAGGATATAGCACTGGTTGTTGCAAAATGGACTGGAATACCT
GTTGCAAGACTAACAGAGACACAGGCAGAGAAACTGTTACATATAGAGGAAGAGCTACACAAAAGGGTTGTTGATCAGTC
TGAGGCTATAGAAGCAATAGCAAAGGCTATAAGAAGAAACAGTGTTGGTCTGAAAGGAACACACAGACCTATAGGTGTGT
TTATGTTCCTCGGTCCAACAGGTGTTGGTAAGACTGAAACAGCTAAGGCCCTTGCTGAGTATCTGTTTGGAACTGAAGAG
GCACTTATAAGGTTTGATATGTCTGAGTATATGGAAAAACATACAGTATCAAGGCTTGTTGGAGCACCTCCAGGATATGT
TGGGTATGAGGAAGGAGGTCAGCTTACAGAAGCTGTGAGAAGAAGACCTTACTCAGTGATACTTTTTGATGAGATAGAGA
AAGCACATCCCGATGTGTTTAACATATTCCTCCAGATATTTGATGATGGAAGACTTACAGACTCTTTTGGAAGGGTTGTT
GATTTCAGCAATACTATAATAATCATGACTTCTAACCTTGGAGCAAGACTTATACTTGAATCAAACAGACTTGGATTTGA
AAGATCAACAGGAATGCTTGAATACAACGAGATGAAGAAGAATGTTCTCCAGCAGGTTAAGAAACATTTCAGCCCCGAGT
TCCTTAACAGACTTGACGAGATAATAGTATTCAAGCCTCTGGACAAAGAAGTTATAAAAGGTATAATTGATATTCAGCTT
AAGGAAATAAACAAAAGGTTAAAGGAATGGGGCATAACTGTAAAACTTACGAAGAAGTTCGTAGAGTATCTGATAGAGAA
AGAGTTCAGACCGGAATTTGGAGCAAGAAGTATAAAGAGAGCCCTCCAGTCACTTGTAGAGGATCTTTTAGCGGAAGAGA
TACTGAAAGGGAAGATAACAGAAGGCTCTGTGGCAGAAGTTACTGTGAAGAAGGATGGTCAGGTTGGAATAAAGGTAAAA
AGACCAAAAACACAGAAAAAAGCGAAGAAAAAAGAAGTAGCAGCAACATAA

Protein sequence :
MFEKFTERARKVILNAREKALEYRSNYLGSEHLLLSLLEEEDIPVLVLSRFGLTVDKVKRTLTSQMVHGSHSGEVLFAPD
AKRVLEFAVEEARILHHQFVGPEHLLIGIVREKTGLGGRVLRGFGIDEYSIRREILQILGEIPPQEQVKQVPTPNIDRFS
RDLTALAREGKLDPVIGRDKEIDRVIQILSRRRKNNPVLIGEPGVGKTSIVEGLAQRIANKEVPETLQSKRIVALDLAAL
VAGTKYRGQFEERLKNILKELEKAPYIILFIDELHTLVGAGAAEGSIDASNMLKPALARGEIQVIGATTIDEYRKYIEKD
GALERRFQPVLVEPPTPEDTVKILMGLKKKFEEFHEVEYTKDAVEKAVEYSVKYITERQLPDKAIDLIDEAGAWVRIREM
ELPPKLKKIEDKIRKIEEEKAKAAKEQDYEKAAKLRDEELKLRAKFETLKAEWKEKRKVKKPKVKDQDIALVVAKWTGIP
VARLTETQAEKLLHIEEELHKRVVDQSEAIEAIAKAIRRNSVGLKGTHRPIGVFMFLGPTGVGKTETAKALAEYLFGTEE
ALIRFDMSEYMEKHTVSRLVGAPPGYVGYEEGGQLTEAVRRRPYSVILFDEIEKAHPDVFNIFLQIFDDGRLTDSFGRVV
DFSNTIIIMTSNLGARLILESNRLGFERSTGMLEYNEMKKNVLQQVKKHFSPEFLNRLDEIIVFKPLDKEVIKGIIDIQL
KEINKRLKEWGITVKLTKKFVEYLIEKEFRPEFGARSIKRALQSLVEDLLAEEILKGKITEGSVAEVTVKKDGQVGIKVK
RPKTQKKAKKKEVAAT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 2e-163 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
PERMA_1739 YP_002731503.1 negative regulator of genetic competence ClpC/mecB VFG0079 Protein 0.0 53