Gene Information

Name : serS (PERMA_1558)
Accession : YP_002731325.1
Strain : Persephonella marina EX-H1
Genome accession: NC_012440
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1505851 - 1507110 bp
Length : 1260 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGATATAAAGCTGATTAGATCTAACCCTGAATTTGTGAAGGAGAGATTATCAAAGAGAGACCCTGCATACGAGAA
GATGATTGATGAGATACTTGATGTTGACGAGGAGAGGAGAAGGATAATAAAGGAGGTTGAGGATCTCAAAGCAGAGAAAA
ACAGACTATCTAAAGAGATAGGTCTTCTTTTCAGAGAAGGTAAAAAAGAAGAAGCAGAAAAAGTAAAGGATGAGGTTCAG
GCAAAAAACAAAAAGATAGAGAGGCTTGAGAGGGATCTTAAGGATATTGAAAAAAGGTTTAACTACCTTCTTCTCACAGT
TCCAAACATTCCCCATGAGACAGTCCCAGTAGGTGAGGATGAGGAGGACAACGTTGAGATAAGAAGATGGGGAGAACCGA
GAAAGTTTGATTTTGAACCTCTACCACACTGGGATATTGGGGAAAAACTCGGGATACTTGATTTTGAAAGGGGAGCTAAA
CTTTCAGGCTCAAGATTTACAGTTATGTACAGTGAAGCAGCAAGATTAGAGAGAGCGTTGATAAACTTTATGCTTGATCT
TCATACAAAAGAACACGGATACACAGAGGTATGGACGCCTGTCCTTGTCAGATCAGAGATACTTGTAGGAACAGGACAGC
TACCAAAATTTGAGGAAGACCTTTACAGAATAAGTGAGGAGGATCTTTATCTCCTTCCAACAGCTGAGGTATCACTCACA
AACCTGCATGCTGGAGAGATACTGAAGGAGGAAGAACTCCCAAAGTACTACACTGCGTACACACCCTGTTTTAGAAGGGA
AGCAGGATCTCACGGAAAAGATGTGAGAGGAATTCTCAGACAGCACCAGTTTGATAAGGTTGAGCTTGTTAAGATAGTAA
AACCAGAAGACTCGTATGAAGAGCTTGAAAAGCTTGTAAGAGAGGCCGAAAAGGTATTACAGCTGCTTGAGCTTCCATAC
AGGGTTGTTGAGCTTTGCACAGGTGATCTCGGTTTTTCAGCAGCAAAAACATATGATATAGAGGTATGGATACCTTCACA
GAAAAGGTACAGGGAGATATCTTCATGCTCAAACACAGAGGACTTTCAGGCGAGGAGAGCGAAGATAAGATTTAAGGATA
AAGATGGTAAAAACAGGTTTGTTCACACACTTAACGGATCAGGTCTTGCAGTAGGAAGAACACTCCTTGCGATAATGGAG
AACTACCAGAGGGAAGACGGAAGTTTTGATATTCCGGAGATCTTAAAAAAATATATGTAA

Protein sequence :
MLDIKLIRSNPEFVKERLSKRDPAYEKMIDEILDVDEERRRIIKEVEDLKAEKNRLSKEIGLLFREGKKEEAEKVKDEVQ
AKNKKIERLERDLKDIEKRFNYLLLTVPNIPHETVPVGEDEEDNVEIRRWGEPRKFDFEPLPHWDIGEKLGILDFERGAK
LSGSRFTVMYSEAARLERALINFMLDLHTKEHGYTEVWTPVLVRSEILVGTGQLPKFEEDLYRISEEDLYLLPTAEVSLT
NLHAGEILKEEELPKYYTAYTPCFRREAGSHGKDVRGILRQHQFDKVELVKIVKPEDSYEELEKLVREAEKVLQLLELPY
RVVELCTGDLGFSAAKTYDIEVWIPSQKRYREISSCSNTEDFQARRAKIRFKDKDGKNRFVHTLNGSGLAVGRTLLAIME
NYQREDGSFDIPEILKKYM

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 3e-105 57