Gene Information

Name : hemC (SULAZ_0549)
Accession : YP_002728539.1
Strain : Sulfurihydrogenibium azorense Az-Fu1
Genome accession: NC_012438
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 492765 - 493691 bp
Length : 927 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
TTGAAGGTAAGGATTGGTACAAGAAAAAGTCAACTTGCACTTTGGCAAGCAAACTACATAGCTAACTTAATTAATCAAAT
TCACGGTGTAGAAGTAGAGCTTGTAAAAATTACTACATCAGGAGACAAAATATTAGACGTCCCCCTTGCAAAGATAGGAG
GTAAAGGTCTCTTTGTAAAAGAGATAGAAGATGCAATGTTAAAAGGTGAGATAGATATAGCCGTTCACTCTCTTAAAGAT
GTTCCTACACAGCTCCCTGAAGGACTTGATATAATTGCAATAACAGAAAGAGAAGACCCAAGAGATGCTTTCTTATCTAC
TAAATATAAATCTTTAAAAGACCTACCAGCCGGTGCAGTAGTTGGGACAAGTAGTTTAAGAAGAAAGTCTCAAATTATGA
AAATGAGAGATGATTTAATAATAAATGATTTAAGAGGAAACGTTGACACAAGGATAAGAAAACTTGAAGAAGGTCAGTAC
GATGCTATAATCCTTGCCTATGCTGGCTTAAAAAGGTTAGGACTTGATAGTAAAGCTTCCTACATCTTTTCTCCCCAAGA
GATGATTCCTGCCGTTTGTCAAGGATTTTTAGGTATTGAGGCAAGGGTTGACGATGAAAGAATAAAGAAAATTTTAGAGC
CGATAAACAACCAAGAAAGTTTTATAAGGGCAACTGCAGAAAGGAGCTTCTTAAAAACACTAGAGGGAGGATGTCAGGTT
CCACTGGGAGCTTACTGTGAGATTAAAGATGACTTTATTCATATAACAGGCTTTATAGCAGATTTAGAAGGAAAAACATT
TATAAAAGAGAGTTTATCAGAGAAGTTAACTAACATAAATCAAGCAAAAGAGTTAGGGCAAAGGCTTGCAAACATACTAC
TTAAAAGAGGTGGTAAAGATATACTAACTAAAATTTACAACTTATGA

Protein sequence :
MKVRIGTRKSQLALWQANYIANLINQIHGVEVELVKITTSGDKILDVPLAKIGGKGLFVKEIEDAMLKGEIDIAVHSLKD
VPTQLPEGLDIIAITEREDPRDAFLSTKYKSLKDLPAGAVVGTSSLRRKSQIMKMRDDLIINDLRGNVDTRIRKLEEGQY
DAIILAYAGLKRLGLDSKASYIFSPQEMIPAVCQGFLGIEARVDDERIKKILEPINNQESFIRATAERSFLKTLEGGCQV
PLGAYCEIKDDFIHITGFIADLEGKTFIKESLSEKLTNINQAKELGQRLANILLKRGGKDILTKIYNL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 2e-71 53
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 2e-71 53