Gene Information

Name : SULAZ_0309 (SULAZ_0309)
Accession : YP_002728304.1
Strain : Sulfurihydrogenibium azorense Az-Fu1
Genome accession: NC_012438
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence ClpC/mecB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 280049 - 282493 bp
Length : 2445 bp
Strand : +
Note : identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728

DNA sequence :
ATGTTTGAGAAATTTACAGAAAAAGCAAGAAAAGTAATACTAACAGCAAGGGAGCATGCATTATCATATAGAAACAACTA
CCTTGGAAGTGAGCATCTTCTCTTAGCACTCCTTGATGAAGATGATATTACAATCTTAGTTCTTTCCAAGTTTGGGCTTA
CAGTTGATAAAGTAAAGAAAACTTTAACTTCTCAAATGTCAAGAGGTAGCCATTCGGGAGAGGTTTTGTTTGCTCCTGAT
GCAAAAAGAATCCTTGAGTTTGCAGTAGAAGAGGCTCGTATTTTACACCATCCATTTGTAGGGCCAGAACATTTACTTAT
AGGTATAATCAGAGAAAAAACAGGTTTAGGTGGAAGAGTACTTAGAGGGTTTGGTATAGATGAGTATAGTGTAAGAAGAG
AGATACTTTCTGCCCTTGGAGAGATACCTTCACAAGAACAAACAAAATCAGCTCCAACACCAAATTTAGACAGATTTGGA
AGAGACCTAACAGCTTTAGCAAAAGAAGGAAAGTTAGACCCTGTTGTAGGTAGAGAAAAAGAAATAGAAAGAGTTATCCA
GATACTCTCAAGAAGAAGAAAAAACAATCCAGTCTTAATAGGAGAGCCAGGGGTAGGTAAAACTGCTATCGTTGAAGGTC
TTGCCCAAAGAATAGCAAACAAACAAGTCCCTGAAACACTTCAAAACAAGAGAATAGTTGCACTGGATTTAGCTTTAATC
GTTGCAGGAACAAAGTACAGAGGACAGTTTGAAGAAAGGTTAAAAAGCATCCTAAAAGAGTTAGAAAAAGCTCCTAACGT
TATACTCTTTATAGATGAACTTCATACAATGGTTGGAGCAGGTTCTGCAGAAGGGTCATTAGACGCTTCTAATATGTTAA
AACCTGCTTTATCAAGAGGAGAGATACAGGTAATAGGAGCTACCACTTTAGATGAATACAGAAAATACATAGAAAAAGAC
GGAGCTCTTGAAAGAAGATTTCAACCAGTTATAGTTGACCCACCATCTCCAGAAAATGCAATACTGATACTGGAAGGTTT
AAAGAAAAAGTTTGAAGAGTTCCATAACGTAGAGTATACAAAAGATGCAATAGAAAAGGCAGTAGAGTTTTCTGTTAAGT
ACATATCAGATAGACAACTACCTGATAAAGCCATAGACCTTTTAGATGAAGCAGGAGCTCTAGTCAGACTTAGAGAGCTT
GAACTCCCAGAAGACCTTAAAAAGATAGAAGAAAAGATAAAAGAGATAGAAGAAGAAAAAACTAAAGCAATTAGGGAAGA
AGACTTTGAAAAAGCGTCTAAGTTAAGAGACGAAGAGGTTAAGTTAAGAGCTAAGTTTGAAACTATGAAGTTAAACTGGA
AAGAACAGCAAAAAGAAAACAGACCTAAAGTTACAGAAAAAGATATTGCAGAAGTTGTAGCAAGATGGACTGGAATACCT
ATAGCAAGATTAACAGAGTCTAACAAAGAAAAACTTCTTCACATAGAAGAAGAACTTCACAAGAGAGTTGTTGACCAAAA
CGAAGCTATAACTGCAATTGCAAAAGCTATAAGAAGAAACAGCGTAGGACTAAAAGGAAGACACAGACCTATAGGAGTAT
TCTTATTCTTAGGACCTACCGGAGTAGGTAAAACTGAGACAGCTAAGGCTTTAGCAGAGTACTTATTTGGGAAAGAAGAT
GCTTTAATAAGGTTTGATATGTCTGAATATATGGAAAAACATACAGTATCAAGACTTATAGGAGCTCCTCCGGGGTACGT
AGGTTACGAAGAAGGCGGACAGCTTACAGAAGCTGTAAGAAGAAAACCTTACTCTGTTATACTTTTTGATGAGATAGAGA
AAGCCCACCCAGACGTGTTTAATATATTCTTACAGATATTTGACGATGGAAGACTTACAGACTCTTTAGGTAGAGTAGTT
GACTTTAGCAACACAATAATAATAATGACGTCAAACCTTGGTGCTAAGATGATTTTAGATAGTGGAAAGATGGGATTTGA
AACAAAATCTTCTCTTGTAGATTACAAGGACCTTAAGAAAAATGTTATGGACCAAGTTAAGAAAGCGTTTAATCCAGAGT
TTGTTAACAGGCTTGATGAGATAATTGTATTCAAACCATTGGACAAAGAGGTGATTAAAGGTATAATAGATATACAAATT
AAAGAGATTAATAAAAGGTTAAAAGAATGGCAAATAGAAGTAAGCTTATCTCCAGAGTTTGTAAACTACTTGATAGAGAA
AGAATTCAAACCAGAGTATGGAGCAAGAAGTATAAAGAGAGCTCTTCAATCTCAAGTAGAGGACTTGTTAGCAGAGGAGA
TACTATCTGGAAAATTACAACCTGGTTCACAAGTGGAAGTAGTATTAAATCCAGACAACACAGTAGGATTAAAAGTTCTA
CAAAAGAAAAAAGGAAGGAAAAAGAAAGAACTTCAACCAGCATAA

Protein sequence :
MFEKFTEKARKVILTAREHALSYRNNYLGSEHLLLALLDEDDITILVLSKFGLTVDKVKKTLTSQMSRGSHSGEVLFAPD
AKRILEFAVEEARILHHPFVGPEHLLIGIIREKTGLGGRVLRGFGIDEYSVRREILSALGEIPSQEQTKSAPTPNLDRFG
RDLTALAKEGKLDPVVGREKEIERVIQILSRRRKNNPVLIGEPGVGKTAIVEGLAQRIANKQVPETLQNKRIVALDLALI
VAGTKYRGQFEERLKSILKELEKAPNVILFIDELHTMVGAGSAEGSLDASNMLKPALSRGEIQVIGATTLDEYRKYIEKD
GALERRFQPVIVDPPSPENAILILEGLKKKFEEFHNVEYTKDAIEKAVEFSVKYISDRQLPDKAIDLLDEAGALVRLREL
ELPEDLKKIEEKIKEIEEEKTKAIREEDFEKASKLRDEEVKLRAKFETMKLNWKEQQKENRPKVTEKDIAEVVARWTGIP
IARLTESNKEKLLHIEEELHKRVVDQNEAITAIAKAIRRNSVGLKGRHRPIGVFLFLGPTGVGKTETAKALAEYLFGKED
ALIRFDMSEYMEKHTVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVILFDEIEKAHPDVFNIFLQIFDDGRLTDSLGRVV
DFSNTIIIMTSNLGAKMILDSGKMGFETKSSLVDYKDLKKNVMDQVKKAFNPEFVNRLDEIIVFKPLDKEVIKGIIDIQI
KEINKRLKEWQIEVSLSPEFVNYLIEKEFKPEYGARSIKRALQSQVEDLLAEEILSGKLQPGSQVEVVLNPDNTVGLKVL
QKKKGRKKKELQPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 2e-172 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SULAZ_0309 YP_002728304.1 negative regulator of genetic competence ClpC/mecB VFG0079 Protein 0.0 53
SULAZ_0309 YP_002728304.1 negative regulator of genetic competence ClpC/mecB VFG0080 Protein 5e-147 52