Gene Information

Name : guaA (WRi_001820)
Accession : YP_002726811.1
Strain : Wolbachia sp. wRi
Genome accession: NC_012416
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 182725 - 184287 bp
Length : 1563 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
TTGTCAGCAATTGCCATTATTGATTTTGGTTCACAGTTTACACAGCTTATCGCAAGACAAGTAAGAGGAATGGGTGTTTA
TTGTGAGATATTTCCAAGCAACATCAGTTTTGAAACAATATCAAAATTCAATGGGTTTATTCTCTCTGGAGGACCACAAT
CTGTAAATGATGATTGTTCTGAAACAAGTAGAGTAGTACATGAAATTATAAAACTTAATGAGGCAACAAGCGTTCCTATA
CTTGGAATATGCTATGGACAGCAACTCATTTGTCATTATTTTGGAGCAAAAGTAAAAGAGAGTTTCAAACAGGAGTTTGG
TAGAACTAAAATCAAGATACTAAAAGAATCCCCCATTGTAAAGGATACCTGGGATGTTAATTCTGAAGTGGATGTATTAA
TGAACCATGCGGACAGTGTTGATACTATACCACAGGGATTTACTGTTATCGCATCAGGTGTGATAAATCAAACAATTGCA
ATGATTGTCAACGAACAGCGGAAGATTTACTGTACTCAGTTCCATCCTGAGGTTAAGCCCACAACAAATGGCAGTAAATT
GCTCTCTAACTTCTTGGATATTGCAAATTGCAAAAGAGACTGGACAATGAAGTCGTTTATTGAGGAGCAAAAGGAAAAAA
TCAAAAATGTAGTAGGAGAGAAAAAAGTAATCGCTGCAGTAAGTGGTGGGGTTGATTCAAGCGTTGCAGCGGCTCTCACA
CATAAAGCTATAGGAAAACAATTGAACTGTATTTTTATCGATACTGGGTTGTTACGCAAGAACCAAACCATCGCTATGTT
GAAAGAGATTCCGATAAATTACGTTGATAAATCAAATTTATTTTTGAGTAGGTTGAAGGGAATAACTGATCCAGAAGAAA
AGCGAAAAATTATCGGTAACACTTTTATTGAAGTGTTTGAAGAAGAAGCAAAAAAAATAGGTGATGTGGATTTTTTGATG
CAAGGTACCATCTACTCTGATGTAGTTGAGTCAGGGCATGCCTCAGACAACACTAGTACAATTAAGTCTCACCATAATGT
TGGTGGGTTGCCAGAAAAGATGAATCTGAAGTTAGTGGAGCCTTTACGTTACCTCTTTAAAGATGAGGTAAGGCTACTTG
GAAAAGAAATTGGGCTTTCAGACGAGATAATATTTCAACATCCATTTCCTGGACCCGGACTTGCAGTGAGGATTATAAGT
GAAGTCGATAAAGAAAAGGTGCAAATATTGCAAGAAGTAGATGAAATATATATTAATACGATGAAAAATTACGATCTATA
TGATAAGATATGGCAAGCTTTTGCTGTATTATTACCAATAAAAACTGTAGGCGTTATGGGAGATGGTCGTACGTATGGAT
ATGTTTGTGCTTTAAGGGCTGTAACATCATCTGATGGTATGACAGCCGATGCATTTCCATTTGAAGATAAGGATCAACAC
TTGCTAGTATTTTGGGATTTTTTACGTAATGTCGGCAGTATAATTGTTAATAATGTTCCCGGAGTAAATAGAGTTGTTTA
TGATATCACTTCTAAACCACCCGCAACTATTGAGTGGGAGTAA

Protein sequence :
MSAIAIIDFGSQFTQLIARQVRGMGVYCEIFPSNISFETISKFNGFILSGGPQSVNDDCSETSRVVHEIIKLNEATSVPI
LGICYGQQLICHYFGAKVKESFKQEFGRTKIKILKESPIVKDTWDVNSEVDVLMNHADSVDTIPQGFTVIASGVINQTIA
MIVNEQRKIYCTQFHPEVKPTTNGSKLLSNFLDIANCKRDWTMKSFIEEQKEKIKNVVGEKKVIAAVSGGVDSSVAAALT
HKAIGKQLNCIFIDTGLLRKNQTIAMLKEIPINYVDKSNLFLSRLKGITDPEEKRKIIGNTFIEVFEEEAKKIGDVDFLM
QGTIYSDVVESGHASDNTSTIKSHHNVGGLPEKMNLKLVEPLRYLFKDEVRLLGKEIGLSDEIIFQHPFPGPGLAVRIIS
EVDKEKVQILQEVDEIYINTMKNYDLYDKIWQAFAVLLPIKTVGVMGDGRTYGYVCALRAVTSSDGMTADAFPFEDKDQH
LLVFWDFLRNVGSIIVNNVPGVNRVVYDITSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-112 48
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-112 48
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-112 48
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-93 41