Gene Information

Name : fliI (BHWA1_00666)
Accession : YP_002720864.1
Strain : Brachyspira hyodysenteriae WA1
Genome accession: NC_012225
Putative virulence/resistance : Virulence
Product : flagellar biosynthesis/type III secretory pathway ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 795318 - 796772 bp
Length : 1455 bp
Strand : -
Note : -

DNA sequence :
ATGATTAAAGATGAAAATGTAGATTTTGATAAAGAAGTAAAAAAGACATTTGATAAATACAGAAAAGTAGTTGATGATGT
AGCTTTATTAAAATCTTACGGTAAAGTTAAAGAAGTTATAGGTTCATTGGTTATTAGTGAAGGACCTTTTTGCAAACTTG
GCGATATGTGCCGTATATATATGAATGACAATAGTTATCTTGATGCTGAAGCTATAGGTTTCAGAAATCAAGATGTACTT
TTAGCTACTTACGGACCTGTTAATGGAATAACTTTTGGAAATATGGTTTATTCTTTTGAAAGACCATTATCTGTTATGTG
CTGTGATGAAATATTAGGAACAGTGCTTGATGCAAGAGGAAAACCGCTTGCAGGAGGCGGGCATAATTTTTATGAAACTC
CTATTCCTGTTTCTCATTCAGCAGTAAACCCAATGAATAGACCTAGAATAAATAAACATATACAAACAGGTGTAAGAGCA
ATAGACGGGCTTTTAACTGTTGGACAGGGACAGCGTATGGCTATAATGAGCGGTACTGGTGTCGGTAAATCTACACTCTT
ATCTATGATAGCTAGAAATACCAATGCTGATGTAAATGTTATCGCATTGATTGGTGAAAGAAGAAGAGAGGTAAGAGATT
TTATAGAAAGAGATTTAGGAGAAGAAGGATTAAAAAGAAGTATATTAGTTGTTGCTACAAGTGATGATGCTCCGCTTTTG
AGAGTAAGAGCTGCATACACTGCTACTACAATAGCTGAGTATTTCAGAGATAAAGGCAAAAATGTTATGTTTATGGTAGA
CTCTGTAACACGTTTTGCTTTGGCTCAAAGAGAGATAGGACTTTCAAGAGGTGAGCCTCCTACCACTAGAGGTTATACTC
CTAGTGTATTCTCTGAACTTGCTAAACTTTTGGAAAGAACAGGTACTTCAAGCAAAGGCTCTATTACAGCATTTTATAAT
GTATTGGTAGAAGGTGATGATTTGGATGAACCTATTACGGATGCTGTTAGAGGTATATTAGACGGACACATAGTTTTATC
TAGAGATTTAGCCAATAGAGGACATTTCCCAGCTATTGATGTAAATAAAAGTATATCTAGGATTATGAATGAAGTAGTAT
CTAATATGCATAAAAGAGCAGCAAGAGAATTTTTAAAGATGAGTGCTGACTATAATGAAGCTAAAGAACTTATAATGATA
GGCGGTTATGCTAAAGGAAGTATGCCTGAAGTTGACAGAGCCATTGATTATAAGCCTATGATGGATAGATATTTACAGCA
AGATGTATATGAGGTTTCAAGTTTTGCTGATAGTAAAGAAGCTCTTTTATCTATGTTCTATTCACAGGAAGAGATAGAAG
AGGATTTAGTAAACAGCGGCGATGTAAAAAAAGCAGCTGATAGAACAGATATTTCCGACAATGTAGAATATGCTAATGAT
GTTGTGATACTGTAG

Protein sequence :
MIKDENVDFDKEVKKTFDKYRKVVDDVALLKSYGKVKEVIGSLVISEGPFCKLGDMCRIYMNDNSYLDAEAIGFRNQDVL
LATYGPVNGITFGNMVYSFERPLSVMCCDEILGTVLDARGKPLAGGGHNFYETPIPVSHSAVNPMNRPRINKHIQTGVRA
IDGLLTVGQGQRMAIMSGTGVGKSTLLSMIARNTNADVNVIALIGERRREVRDFIERDLGEEGLKRSILVVATSDDAPLL
RVRAAYTATTIAEYFRDKGKNVMFMVDSVTRFALAQREIGLSRGEPPTTRGYTPSVFSELAKLLERTGTSSKGSITAFYN
VLVEGDDLDEPITDAVRGILDGHIVLSRDLANRGHFPAIDVNKSISRIMNEVVSNMHKRAAREFLKMSADYNEAKELIMI
GGYAKGSMPEVDRAIDYKPMMDRYLQQDVYEVSSFADSKEALLSMFYSQEEIEEDLVNSGDVKKAADRTDISDNVEYAND
VVIL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 8e-90 50
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 8e-92 48
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-90 48
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 9e-91 48
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-90 48
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-91 48
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 2e-91 48
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 2e-91 48
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-88 48
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-88 48
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-78 46
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-78 46
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-73 45
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 9e-74 45
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-74 45
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 3e-74 45
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-74 45
escN AAC38383.1 EscN Virulence LEE Protein 1e-77 45
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-77 45
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-77 45
escN CAC81862.1 EscN protein Virulence LEE II Protein 2e-77 45
escN YP_003236088.1 translocator EscN Virulence LEE Protein 5e-78 45
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 2e-75 45
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 3e-77 44
escN AAK26715.1 EscN Virulence LEE Protein 4e-77 44
escN AAL57542.1 EscN Virulence LEE Protein 4e-77 44
escN AAC31513.1 L0034 Virulence LEE Protein 8e-78 44
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 8e-78 44
escN NP_290268.1 hypothetical protein Virulence LEE Protein 1e-77 44
ECs4568 NP_312595.1 EscN Virulence LEE Protein 1e-77 44
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 3e-75 44
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 2e-75 44
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 2e-75 44
unnamed AAL06369.1 EscN Virulence LEE Protein 3e-79 43
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 7e-76 43
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 5e-76 43
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 3e-74 43
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 1e-75 43
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 3e-81 43
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 8e-72 42
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 6e-80 42
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 6e-70 42
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 6e-70 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_002720864.1 flagellar biosynthesis/type III secretory pathway ATPase VFG2144 Protein 1e-93 48
fliI YP_002720864.1 flagellar biosynthesis/type III secretory pathway ATPase VFG0390 Protein 2e-90 48
fliI YP_002720864.1 flagellar biosynthesis/type III secretory pathway ATPase VFG0192 Protein 6e-92 48
fliI YP_002720864.1 flagellar biosynthesis/type III secretory pathway ATPase VFG1254 Protein 2e-89 48
fliI YP_002720864.1 flagellar biosynthesis/type III secretory pathway ATPase VFG2499 Protein 3e-87 46
fliI YP_002720864.1 flagellar biosynthesis/type III secretory pathway ATPase VFG2331 Protein 3e-84 45
fliI YP_002720864.1 flagellar biosynthesis/type III secretory pathway ATPase VFG0048 Protein 1e-86 45
fliI YP_002720864.1 flagellar biosynthesis/type III secretory pathway ATPase VFG0515 Protein 5e-74 45
fliI YP_002720864.1 flagellar biosynthesis/type III secretory pathway ATPase VFG0730 Protein 6e-78 45
fliI YP_002720864.1 flagellar biosynthesis/type III secretory pathway ATPase VFG0812 Protein 4e-78 44