Gene Information

Name : BHWA1_00436 (BHWA1_00436)
Accession : YP_002720605.1
Strain : Brachyspira hyodysenteriae WA1
Genome accession: NC_012225
Putative virulence/resistance : Unknown
Product : N-6 DNA methylase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : -
Position : 489882 - 491384 bp
Length : 1503 bp
Strand : +
Note : -

DNA sequence :
ATGCTTGCTTCAGAAAATGATAAAGATATAAAAAAAGAGCTATGGGCTGCTTCTGATAAATTAAGAGGTAATATAGACGC
TTCAGAATATAAGCATGTAATACTTGGGCTTGTATTTTTAAAATATATATCTGATAAATTTGAAATAAGATATAATGAGC
TTGTAAAAGAAGGATTTGATATGCAAGACGATGCAGAGGCATACAGAGAAAAAAATATATTCTATTTGCCTGAGGAGTCA
AGATTCGATTATATATCATCGCATGCACGTTCTGATGAGATAGGTGCTATTATAGACGAGGCTATGCTTAAAATAGAAGA
AAATAATAAAAAATTGAAAGGTATACTTCCTAAAAATTACAGCCGTCCTGAACTTGATAAAAGAAGGCTAGGGGAGATAA
TAGATTTATTTTCTAATATAAAAATAGCCAATAAAAATAAAAAAGATATATTGGGAAATGTGTATGAATATTTTTTATCG
CAATTTGCAACTGCCGAAGGAAAAAGAGGCGGAGAGTTCTATACGCCATCGCCAATAGTTAAACTTTTAGTTGAAATATT
AGAACCATATAAAGGTAGAATATATGACCCTTGCTGCGGAAGCGGAGGAATGTTCGTACAGAGTGCAAAGTTTTTAGAGG
CACATTCTGAAAGTGTAAATAATATATCTGTATACGGACAGGAAAGCAACCCTACAACTTGGAAGCTATGTAATATGAAT
GTAGCAATACATGGAATAGACGGCAATTTGGGAAAGAATAATGCGGATACTTTTTTTGAAGATTTGCATAAAAATTTGAA
AGCGGATTATATATTAGCGAATCCTCCTTTTAATATGTCAGATTGGGGAGCAGATGCTTTAAAAGATGATTATCGCTGGA
AATGGGGCATTCCTCCAAATGGAAATGCGAATTACGGCTGGCTTTCTCATATAGCGTCAAAATTATCAGAAAGCGGTAAA
GCTGGTGTGGTATTAGCAAACGGCTCTCTTTCTACTCAAACATCAGGCGAGGGTTTAATAAGACAGAATATGATAAAAGA
TGATTTGATAGAATGCATAATATCTCTTCCTACTCAATTATTTATATCAACTCAAATACCTGTTTCATTATGGTTTTTGA
ATAAGGATAAAAAGCAGAAAGGACATATACTTTTTATAGATGCAAGAAATTACGGTAGAATGGAGAGCAGGGTTCAGAGG
GTTTTAGATGATGATGATATAGAAGCAATAGCAAAAACTGTTCATAGCTGGCAGAAAGGCAAAGGCTATAAAGATATAAA
AGGATACTGCAAAAGTGCTTCTTTGGAAGAGATATCAAAAGAAGATTATATACTTACAACAGGCAGATATGTAGGGCTTG
AAGAAGAGGATAATAAGGAAGAAGATTTTGATGCGAAGATGAAAGTTTTAACAGAAGAATTGGGCGAATGTTTTAAAGAA
AGCAGGAAATTGGAAAAGATAATAAAGGATAATTTAGAGGAAATAGGCTATAGTATTAAATAA

Protein sequence :
MLASENDKDIKKELWAASDKLRGNIDASEYKHVILGLVFLKYISDKFEIRYNELVKEGFDMQDDAEAYREKNIFYLPEES
RFDYISSHARSDEIGAIIDEAMLKIEENNKKLKGILPKNYSRPELDKRRLGEIIDLFSNIKIANKNKKDILGNVYEYFLS
QFATAEGKRGGEFYTPSPIVKLLVEILEPYKGRIYDPCCGSGGMFVQSAKFLEAHSESVNNISVYGQESNPTTWKLCNMN
VAIHGIDGNLGKNNADTFFEDLHKNLKADYILANPPFNMSDWGADALKDDYRWKWGIPPNGNANYGWLSHIASKLSESGK
AGVVLANGSLSTQTSGEGLIRQNMIKDDLIECIISLPTQLFISTQIPVSLWFLNKDKKQKGHILFIDARNYGRMESRVQR
VLDDDDIEAIAKTVHSWQKGKGYKDIKGYCKSASLEEISKEDYILTTGRYVGLEEEDNKEEDFDAKMKVLTEELGECFKE
SRKLEKIIKDNLEEIGYSIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 3e-144 58
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 1e-144 58
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 1e-145 58
api49 CAF28523.1 putative HsdM-like N-methyl transferase Not tested YAPI Protein 8e-109 46