Gene Information

Name : pyk (BHWA1_00011)
Accession : YP_002720187.1
Strain : Brachyspira hyodysenteriae WA1
Genome accession: NC_012225
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 8100 - 9533 bp
Length : 1434 bp
Strand : +
Note : -

DNA sequence :
ATGAGAAAAACAAAAATAATAGCAACTTTAGGCCCAAGATGGTCTAATGAAGATATGGTAAGAAAAATTATAGAAAATGG
AGCTGATGTATGCCGACTAAATTTTTCTTTCGGAACTTATGATGAACATTTAGAGAGAATAAATATAATAAGAAAGGTTT
CAAATGATTTAAAAAAACCTGTGGCAATATTGGCAGATTTACAGGGTCCTAAAATAAGAATAGGTAAATTAAAAGAGTCT
ATTACTGTAAAAGAAGGTGATATAGTAAAACTTAGCGGATATAAAGAAACTAATGATGATAGTATTATACCAACAACACA
TTCTAATATTGCTCATGATGTTAAATCAGGTTCTATGCTTTTGATAGCTGACGGTACAATACAGCTTATAGTTGAATCTA
GTGATGAGGCATCAAAACTTGTAGTGTGTAAAGTTATAACAGGAGGTACTATATTAAGCAGTAAAGGAATTAATCTTCCT
GGAGCACATGTTACAACAGAAGTTCTAACTGAAAAAGATGTAAGCGATGCTTTATTTGCTGCTAAGAATGGTGTTAATTA
TTTAGGAATGAGTTTTGTAAGAAAGGCTGAAGATGTTATAAGACTTAGAAAGATATTAGATGATAATAATCTTCAAGATG
TAGGTATTGTTTCAAAGATAGAAAATACTGAATCTCTTGAGAATTTAGAGGAAATTATAAAACATTCTGATGGTGTAATG
GTGGCTAGAGGAGATTTAGGTGTTGAGATACCATTTGGAGAAGTACCTGTTTGGCAGAAAAAGATATTAAGAATGGCAAA
TGATATAGGAAAAATAACTATTATAGCTACTCAAATGCTTGAAAGTATGACTAAAAGCCCTGTGCCTTCAAGAGCTGAGG
CTAGTGATGTTGCTAATGCTGTTTTAGATGGTACAGATGTTGTAATGATGTCTGCAGAAACTGCTTCCGGTGATTATCCT
ATAGAATCAGTTAAGGCTATGGTTTCAATAGTTGAGGCGGCTGAGAAATCTGTTATGAGAGCTTCACATGAAAATATGTC
TTATTTGGATAGAGGTGTAAATGATGCTCTTACTGATAGTGCTTCTTATTTATCATATTGTTTAGACAATAAAGTAATAA
TAGCTCTTTCAAGATCAGGATATACTGTTAAAAACTTATCTAAAAAAAGACCTAAAACACCTATTGTTTTTATGTCTGCT
GATCCTGATTTATGTAACAGACTCGCTATATGTCATAATGTTTATACTATACTCATGCCTGAAGATTTGAATTTTAGTGC
CGGTATAAGTCATGGAGGTCAGATTGATGTACTTGAAGATACATTAATCAAACATAATTTAGCTAATCATGGCGATAAAG
CTATACTTGTCAGCGGAAGCAAATGGCAGGGTAGATGGCAGGAAAATAGTGTACGTGTAGTTGTTATACACTAA

Protein sequence :
MRKTKIIATLGPRWSNEDMVRKIIENGADVCRLNFSFGTYDEHLERINIIRKVSNDLKKPVAILADLQGPKIRIGKLKES
ITVKEGDIVKLSGYKETNDDSIIPTTHSNIAHDVKSGSMLLIADGTIQLIVESSDEASKLVVCKVITGGTILSSKGINLP
GAHVTTEVLTEKDVSDALFAAKNGVNYLGMSFVRKAEDVIRLRKILDDNNLQDVGIVSKIENTESLENLEEIIKHSDGVM
VARGDLGVEIPFGEVPVWQKKILRMANDIGKITIIATQMLESMTKSPVPSRAEASDVANAVLDGTDVVMMSAETASGDYP
IESVKAMVSIVEAAEKSVMRASHENMSYLDRGVNDALTDSASYLSYCLDNKVIIALSRSGYTVKNLSKKRPKTPIVFMSA
DPDLCNRLAICHNVYTILMPEDLNFSAGISHGGQIDVLEDTLIKHNLANHGDKAILVSGSKWQGRWQENSVRVVVIH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-63 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-63 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-63 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 6e-63 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_002720187.1 pyruvate kinase VFG0479 Protein 1e-63 43