Gene Information

Name : murD (EpC_07410)
Accession : YP_002647771.1
Strain : Erwinia pyrifoliae Ep1/96
Genome accession: NC_012214
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 863495 - 864811 bp
Length : 1317 bp
Strand : +
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGGCTGACTATCAGGGTAAAAAAGTGGTCATTATCGGGTTGGGGCTGACCGGTCTCTCCTGTATTGATTTCTTTATCGC
GCGCGGCGTTGTGCCGCGCATGATAGATACCCGTGTCGTGCCGCCGGGGCTGGAAAAGCTGCCGAAAAACGTGGAGTGCT
GGCTGGGGTCGATGAACGATAGCTGGCTGCTGGACGCCGATCTGATTGTTGCCAGCCCGGGCGTGGCGCTGGCGCATCCT
TCGCTGATGGCTGCGGCGCAAAACGGGGTGGAAATCATTGGCGATATCGAGCTGTTTTGTCGTGAAGCACAGGCACCGAT
CGTGGCGATCACCGGTTCCAACGGCAAAAGCACCGTGACAACGCTGGTTGGCGAGATGGCAAAAGCCGCAGGCTGGCAGG
TTGGCACAGGCGGCAATATTGGCCTGCCTGCACTGACGCTGTTGCAGCAACCGGCACAGCTTTACGTGCTGGAGCTGTCA
AGCTTCCAGCTGGAAACCGCCAGCAGCCTGCACGCGGCGGCGGCGACCATCCTCAACGTGACAGAGGATCATATGGATCG
CTATCCGCTGGGTATGCAGCAATATCGCGCGGCCAAGCTGCGCATCTATGAAAACGCCACGGTCTGCGTGGTTAATGCCG
ATGATGCGATGACCATGCCGGTACGCGGCGCGGATGCGCGCTGCGTGAGCTTTGGTGCCGACGTGGGCGATTATCACCTT
ACGCGCCAGCAGGGCAGTACCTGGCTGCGCGTGCAGGGAGAAAAAGTCCTGAATACCGACGAGATGCACTTGGTCGGTCA
GCACAACTATACCAATGCGCTGGCGGCGCTGGCGCTGGCGGATGCCGTTGGCCTGCCGCGCGCCACCAGCCTGAAAGCCT
TAACCACCTTTAACGGCTTACCGCATCGCTTCCAGCGGGTTCACGAACATAACGGCGTGCGCTGGATTAACGATTCCAAA
GCCACTAACGTTGGCAGCACCGAAGCGGCGCTGAATGGTTTGCATCCGGCTGGCATGTTGTGGCTGTTGCTGGGCGGCGA
CGGCAAGTCGGCGGATTTCAGTCCTCTTACCCGTTATCTGCAGGGCGATCGCATCCGGATTTACTGTTTCGGTCGTGATG
GTGCTGAACTGGCGGCATTGCGCCCGGAGGTAGCGGTGCAGACGGAGACGATGGCCGAAGCGGTGCAGCAGATTGCCACA
CAGGTACAGCCGGGGGATCTGGTGCTGCTGTCGCCCGCCTGTGCCAGCCTTGACCAGTTCAAAAATTTTGAGCAGCGTGG
CGATCTGTTTGCCCAACTGGCGCGGGAGGCTGGCTAA

Protein sequence :
MADYQGKKVVIIGLGLTGLSCIDFFIARGVVPRMIDTRVVPPGLEKLPKNVECWLGSMNDSWLLDADLIVASPGVALAHP
SLMAAAQNGVEIIGDIELFCREAQAPIVAITGSNGKSTVTTLVGEMAKAAGWQVGTGGNIGLPALTLLQQPAQLYVLELS
SFQLETASSLHAAAATILNVTEDHMDRYPLGMQQYRAAKLRIYENATVCVVNADDAMTMPVRGADARCVSFGADVGDYHL
TRQQGSTWLRVQGEKVLNTDEMHLVGQHNYTNALAALALADAVGLPRATSLKALTTFNGLPHRFQRVHEHNGVRWINDSK
ATNVGSTEAALNGLHPAGMLWLLLGGDGKSADFSPLTRYLQGDRIRIYCFGRDGAELAALRPEVAVQTETMAEAVQQIAT
QVQPGDLVLLSPACASLDQFKNFEQRGDLFAQLAREAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 4e-62 43
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 4e-62 43