Gene Information

Name : thyA (EpC_28730)
Accession : YP_002649854.1
Strain : Erwinia pyrifoliae Ep1/96
Genome accession: NC_012214
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 3160603 - 3161397 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAACAGTATCTGGCATTAATGCAGCATGTGCTTGAGCAGGGCACGCCGAAAGACGATCGTACCGGCACCGGTACGCT
GTCAATCTTTGGCCACCAGATGCGTTTCAACCTGCAACAGGGCTTTCCGCTGGTCACCACTAAAAAGTGCCATCTGCGTT
CGATTATTCATGAGCTTTTGTGGTTCCTGAATGGCGACACCAATACGGCTTATCTGAAAGAAAATAAGGTGTCGATCTGG
GACGAATGGGCGGACGAAAACGGCGATCTCGGCCCGGTCTACGGCAAGCAGTGGCGCAGCTGGGGAACCGCAGACGGGCG
ACAGATTGACCAGTTGAGCAAGGTTATCGAACAGCTTAAAAGCGATCCTGACTCAAGGCGTATTATTGTTTCGGCCTGGA
ATGTCGGCGAGCTGGAGCAGATGGCGCTGGCGCCGTGCCACGCCTTTTTCCAGTTCTACGTGGCGCAGGGGAAGCTCTCC
TGCCAGCTGTATCAGCGTTCTTGCGATATTTTCCTCGGTCTGCCGTTCAACATTGCCAGCTATGCTTTGCTGTTACACAT
GATCGCGCAGCAGTGCGACCTCGAAGTGGGCGATTTTGTCTGGACCGGCGGAGATACCCACCTGTACAGCAATCACCTGG
AACAGGCTCGTTTACAGCTGCAGCGTGAACCGCGCGCGTTGCCAAAACTGGTGATTAAGCGTAAACCGGCCTCGCTGTTT
GACTATTGTTTCGACGATTTTGAGATTGAAGGTTACGATCCGCACCCGGCGATTAAAGCGCCGGTGGCCATCTGA

Protein sequence :
MKQYLALMQHVLEQGTPKDDRTGTGTLSIFGHQMRFNLQQGFPLVTTKKCHLRSIIHELLWFLNGDTNTAYLKENKVSIW
DEWADENGDLGPVYGKQWRSWGTADGRQIDQLSKVIEQLKSDPDSRRIIVSAWNVGELEQMALAPCHAFFQFYVAQGKLS
CQLYQRSCDIFLGLPFNIASYALLLHMIAQQCDLEVGDFVWTGGDTHLYSNHLEQARLQLQREPRALPKLVIKRKPASLF
DYCFDDFEIEGYDPHPAIKAPVAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 2e-84 64
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 1e-55 44