Gene Information

Name : tpx (EpC_17130)
Accession : YP_002648721.1
Strain : Erwinia pyrifoliae Ep1/96
Genome accession: NC_012214
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : 1.11.1.-
Position : 1944645 - 1945148 bp
Length : 504 bp
Strand : -
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein

DNA sequence : 
ATGTCTCAGACCGTACATCTTCAGGGCAATCCGGTTTCCGTAGATGGCCAGCTGCCCACCAAAGGCCAGGCGGCAAAGCC
ATTTACCCTGGTAGCCAAAGACCTTTCAGATGTCTCACTGTCTCAGTACGCGGGTAAACGCAAGGTGTTGAATGTTTTCC
CCAGCGTTGATACGGGATTGTGTGCCACTTCCGTTCGCAAATTTAACCAGCTGGCCAGTGAGATCGATAATGCCGTGGTA
TTGTGCATTTCTGCTGACTTGCCGTTCGCACAGTCACGCTTCTGCGGCTCAGACGGTCTGAACAACGTGGTGACCCTTTC
CACCCTGCGCGGCCACGCCTTCCTGAAAGATTATGGCGTGGCGATCGTCGATGGCCCCTTAAGCGGCCTGGCTGCCCGTG
CCGTCATCGTCCTGGACGAAAACGATATGGTCATTTATAGCCAGCTGGTCAATGAAATCTCCACAGAACCCGATTACGAT
GCGGCTCTTGCAGCCTTGAAATAG

Protein sequence : 
MSQTVHLQGNPVSVDGQLPTKGQAAKPFTLVAKDLSDVSLSQYAGKRKVLNVFPSVDTGLCATSVRKFNQLASEIDNAVV
LCISADLPFAQSRFCGSDGLNNVVTLSTLRGHAFLKDYGVAIVDGPLSGLAARAVIVLDENDMVIYSQLVNEISTEPDYD
AALAALK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 8e-33 47
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 1e-32 47
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 6e-33 47
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 2e-32 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_002648721.1 thiol peroxidase VFG0087 Protein 2e-33 47