Gene Information

Name : cvrA (EpC_16260)
Accession : YP_002648636.1
Strain : Erwinia pyrifoliae Ep1/96
Genome accession: NC_012214
Putative virulence/resistance : Unknown
Product : potassium/proton antiporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG3263
EC number : -
Position : 1848407 - 1850128 bp
Length : 1722 bp
Strand : -
Note : the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli

DNA sequence :
TTGGAAGCCAGCGCGATTTACAGTCTCTTCATCATTGGTTCAGTGCTGGTTGCCGCAAGCATTTTGCTCAGCTCTTTTTC
CTCCAGATTAGGGATCCCGATCCTGGTTATTTTCCTTGCCCTTGGCATGCTGGCTGGCGTAGACGGCATCGGTGGCATCG
CCTTTGATAACTACCCCGCCGCATACCTGATAAGCAATCTGGCTCTTGCGGTGATCTTACTTGATGGTGGAATGCGCACC
CAGGCCAGTTCTTTTCGCGTCGCTTTAGGTCCGGCGCTTTCACTGGCAACGGTTGGTGTTCTGATCACCGCCGGGCTGAC
CGGACTGGCCGCCGCGTGGCTGTTCGATCTGAATGTGCTTAACGGTTTTCTGGTCGGTGCGATAATTGGCTCCACCGACG
CGGCAGCGGTTTTCTCACTGTTGGGCGGCAAAGGCCTGAATGAACGCGTCAGCGCCACGCTGGAAATCGAATCGGGCAGC
AATGACCCGATGGCCGTTTTTCTCACCATCACGCTGATTGAGATGATCCAACAGGGGCAAACGGGGCTTAGCTGGATGTT
TGTCGTACATCTGGTTCAACAATTCGGCCTGGGTATTGTACTCGGTCTGGGCGGCGGCTGGGCGCTGCTGCAGGTGATCA
ACCGCGTGTCGCTGGCCAGCGGCCTTTACCCTCTGCTGGCAGTCAGTGGTGGCATTCTGGTTTTCTCGCTCACCACCGTG
CTGGAAGGCAGCGGTATCCTTGCCGTTTATCTGTGTGGTTTTGTGCTAGGCAACCGCCCAATCCGCAACCGCCACGGTAT
TCTGCAAACTTTTGATGGCATGGCATGGCTAAGCCAAATTGGAATGTTCCTGGTGCTGGGACTGCTGGTTAATCCCGCTG
ACCTCTGGCGTATTGCTCTACCGGCTACCCTGCTTTCTCTCTGTCTGATACTGGTTGCTCGCCCGCTCTCGGTGATCATC
GGGCTGTTACCTTTCCGTGGGTTTAATATTCGCGAGCGTATGTTCATCAGCTGGGTAGGATTGCGCGGTGCGTTACCGAT
CATTCTCGCGGTATTTCCGATGATGGCGGGCTTACCTCACGCGGCGCTGTTCTTTAATATCGCCTTCTTCGTGGTGCTGG
TTTCACTGATGGTTCAGGGCACTTCACTCGGATGGGCCGCACGTAAAGCACGGGTGGTGGTGCCACCGCTGGCGTCGCCC
ATCTCCCGCATCGGGCTGGATATTCACCCTGAAAACCCTTGGGAACAGTTTGTTTACCAGCTCAGCGCCGATAAATGGTG
CATCGGTGCAGCACTGCGCGATCTGCGCATGCCGCGCGAAACACGTATCGCCGCCCTGTTCCGAAATAACCTGTTGCTCC
ATCCAACCGGCAGCACCCGCCTGAAAGTCAATGATGTGTTATGCGTTATTGGCCGTGAGCGCGATCTGGCAGCACTGGGC
AAACTGTTCAGCCAATCGCCGCCGGTGTCGTTAGATCAACGTTTCTTTGGTGACTTTATTTTGCAGGCAGACGCTCTGCT
ACAGGATGTTTCACAAATCTACGGCATTGAACTGGATGAAGAAACGGATACGCAACAAACGCTGGGCCAGCTGGTTTCCG
GCATCATCGGCGGCGCTCCGGTGGTAGGCGATCAGGTAGAGTGGAAAAATATGCTGTGGACGGTCGCCGAGAAAGAAGCT
AACGAAATCGTCAAGATCGGCGTAAAGGTACAGGATGAGTAA

Protein sequence :
MEASAIYSLFIIGSVLVAASILLSSFSSRLGIPILVIFLALGMLAGVDGIGGIAFDNYPAAYLISNLALAVILLDGGMRT
QASSFRVALGPALSLATVGVLITAGLTGLAAAWLFDLNVLNGFLVGAIIGSTDAAAVFSLLGGKGLNERVSATLEIESGS
NDPMAVFLTITLIEMIQQGQTGLSWMFVVHLVQQFGLGIVLGLGGGWALLQVINRVSLASGLYPLLAVSGGILVFSLTTV
LEGSGILAVYLCGFVLGNRPIRNRHGILQTFDGMAWLSQIGMFLVLGLLVNPADLWRIALPATLLSLCLILVARPLSVII
GLLPFRGFNIRERMFISWVGLRGALPIILAVFPMMAGLPHAALFFNIAFFVVLVSLMVQGTSLGWAARKARVVVPPLASP
ISRIGLDIHPENPWEQFVYQLSADKWCIGAALRDLRMPRETRIAALFRNNLLLHPTGSTRLKVNDVLCVIGRERDLAALG
KLFSQSPPVSLDQRFFGDFILQADALLQDVSQIYGIELDEETDTQQTLGQLVSGIIGGAPVVGDQVEWKNMLWTVAEKEA
NEIVKIGVKVQDE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAB61290.1 unknown Not tested PAI I CFT073 Protein 6e-176 78
f536 AAC61706.1 F536 Not tested PAI I CFT073 Protein 6e-176 78