Gene Information

Name : guaA (EpC_10570)
Accession : YP_002648085.1
Strain : Erwinia pyrifoliae Ep1/96
Genome accession: NC_012214
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1215706 - 1217286 bp
Length : 1581 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACGACGGAAAATATTCATAAGCATCGCATCCTGATCCTCGATTTCGGTTCACAGTACACTCAGCTGGTTGCACGTCG
CGTGCGTGAGCTGGGCGTCTACTGTGAACTGTGGGCGTGGGATGTTACCGAAGAGCAGATCCGTGGGTTCAACCCGAACG
GCATCATCCTCTCCGGCGGCCCGGAAAGCACCACCGAGCACGACAGCCCGCGCGCCCCGGATTACGTATTTAACGCCGGC
GTACCGGTGCTGGGCGTGTGCTATGGCATGCAGACCATGGCGCTGCAGCTGGGCGGTAAGGTGGAAGGCTCCAGCGAGCG
CGAGTTCGGCTATGCGCAGGTAGAAGTGAAAAACCAGAGCGCGCTGATCCGCGATATCGAAGATGCCATCAGAGCCGACG
GTAAGCCGCTGCTGGACGTGTGGATGAGCCACGGCGATAAAGTGACCGCCATCCCGTCTGATTTTGTCACCGTTGCCAGC
ACCGATACCTGCCCGTTTGCCATTATGGCTAACGAGGAGAAACGCTTCTACGGCGTGCAGTTCCATCCTGAAGTAACGCA
TACCCGCCAGGGGCTGCGCCTGCTGGAACGCTTCGTAAGTGATATCTGCCAGTGCGAAGCGTTGTGGACTCCTGCTAAGA
TCATCGAAGATGCCGTTGCGCGTTTGCGCGAGCAGGTGGGTGACGACAAAGTGATCCTCGGGCTGTCAGGAGGCGTTGAC
TCATCGGTTACCGCAATGCTGCTGCACCGCGCCATCGGCGACCGTCTGACCTGTGTATTTGTGGATAACGGCCTGCTGCG
CCTGAACGAAGCGGAGCAGGTGATGGAGATGTTCGGCGACCACTTCGGCCTGAATATCATCCATGTGGCGGCGGAAAACC
GCTTCCTTGACGCGCTGGCCGGTACCGACGAACCGGAAGCCAAGCGCAAGATTATTGGTCGCGTATTTGTGGAAGTATTC
GATGAAAAAGCCACTAAGCTTTCTGATGTGAAGTGGCTGGCACAGGGTACTATCTATCCTGATGTGATTGAATCAGCCGC
TTCGGCGACCGGTAAGGCGCATGTGATCAAATCGCACCACAACGTGGGTGGCCTGCCGAAAGAGATGAAGCTGGGGCTGG
TTGAGCCGCTGAAAGAGCTGTTCAAAGATGAAGTGCGCAAAATAGGCCTTGAGCTGGGCTTGCCACACGCCATGCTGTTC
CGCCACCCGTTCCCGGGGCCAGGTCTGGGCGTGCGCGTGCTGGGCGAAGTGAAGAAAGAGTACTGCGACCTGCTGCGCCG
TGCCGATGCTATCTTTATTGAAGAGCTACATAAAGCCGACCTGTACAACAAGGTCAGCCAGGCATTTACCGTGTTCCTGC
CGGTACGTTCCGTTGGCGTAATGGGCGATGGCCGCAAGTACGACTGGGTTGTATCCCTGCGTGCGGTAGAAACCATCGAC
TTTATGACCGCGCACTGGGCGCATCTGCCGTATGAGTTCCTCGGCCGCGTTTCAAACCGCATCATCAATGAAATCGACGG
TATTTCCCGCGTGGTTTACGATATCTCCGGCAAACCACCGGCGACGATTGAGTGGGAATGA

Protein sequence :
MTTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEEQIRGFNPNGIILSGGPESTTEHDSPRAPDYVFNAG
VPVLGVCYGMQTMALQLGGKVEGSSEREFGYAQVEVKNQSALIRDIEDAIRADGKPLLDVWMSHGDKVTAIPSDFVTVAS
TDTCPFAIMANEEKRFYGVQFHPEVTHTRQGLRLLERFVSDICQCEALWTPAKIIEDAVARLREQVGDDKVILGLSGGVD
SSVTAMLLHRAIGDRLTCVFVDNGLLRLNEAEQVMEMFGDHFGLNIIHVAAENRFLDALAGTDEPEAKRKIIGRVFVEVF
DEKATKLSDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKLGLVEPLKELFKDEVRKIGLELGLPHAMLF
RHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETID
FMTAHWAHLPYEFLGRVSNRIINEIDGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 8e-129 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 5e-129 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-129 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-112 48